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Gene Ontology Browser
Term Detail
GO term:collagen biosynthetic process
Synonym: collagen anabolism
Synonym: collagen biosynthesis
Synonym: collagen formation
Synonym: collagen synthesis
GO id:GO:0032964
Definition:The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-abiosynthetic process
                                is-aorganic substance biosynthetic process
                                        is-amacromolecule biosynthetic process
                                                is-aaminoglycan biosynthetic process +
                                                is-aamylopectin biosynthetic process
                                                is-abiotin carboxyl carrier protein biosynthetic process
                                                is-acellular macromolecule biosynthetic process +
                                                is-acollagen biosynthetic process [GO:0032964] (31 genes, 34 annotations)
                                                        negatively-regulatesnegative regulation of collagen biosynthetic process
                                                        positively-regulatespositive regulation of collagen biosynthetic process
                                                        regulatesregulation of collagen biosynthetic process +
                                                is-acutin biosynthetic process +
                                                is-aemericellamide biosynthetic process +
                                                is-aenniatin biosynthetic process
                                                is-aenterobactin biosynthetic process
                                                is-aimmunoglobulin biosynthetic process +
                                                is-aintegrin biosynthetic process +
                                                is-amacrolide biosynthetic process +
                                                is-aMHC class I biosynthetic process +
                                                is-aMHC class II biosynthetic process +
                                                negatively-regulatesnegative regulation of macromolecule biosynthetic process +
                                                is-anitric-oxide synthase biosynthetic process +
                                                is-apoly(3-hydroxyalkanoate) biosynthetic process +
                                                is-apoly(hydroxyalkanoate) biosynthetic process +
                                                is-apolyamine biosynthetic process +
                                                is-apolysaccharide biosynthetic process +
                                                positively-regulatespositive regulation of macromolecule biosynthetic process +
                                                part-ofprosthetic group biosynthetic process +
                                                is-aprotoporphyrinogen IX biosynthetic process +
                                                is-areceptor biosynthetic process +
                                                regulatesregulation of macromolecule biosynthetic process +
                                                is-aRNA biosynthetic process +
                                                is-aS100 alpha biosynthetic process
                                                is-aS100 beta biosynthetic process
                                                is-asuberin biosynthetic process
                                                is-atetrahydrofolylpolyglutamate biosynthetic process
                                                is-athymidylate synthase biosynthetic process +
                                                is-auroporphyrinogen III biosynthetic process +
                                                is-aviral protein biosynthetic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule biosynthetic process
                                                is-aaminoglycan biosynthetic process +
                                                is-aamylopectin biosynthetic process
                                                is-abiotin carboxyl carrier protein biosynthetic process
                                                is-acellular macromolecule biosynthetic process +
                                                is-acollagen biosynthetic process [GO:0032964] (31 genes, 34 annotations)
                                                        negatively-regulatesnegative regulation of collagen biosynthetic process
                                                        positively-regulatespositive regulation of collagen biosynthetic process
                                                        regulatesregulation of collagen biosynthetic process +
                                                is-acutin biosynthetic process +
                                                is-aemericellamide biosynthetic process +
                                                is-aenniatin biosynthetic process
                                                is-aenterobactin biosynthetic process
                                                is-aimmunoglobulin biosynthetic process +
                                                is-aintegrin biosynthetic process +
                                                is-amacrolide biosynthetic process +
                                                is-aMHC class I biosynthetic process +
                                                is-aMHC class II biosynthetic process +
                                                negatively-regulatesnegative regulation of macromolecule biosynthetic process +
                                                is-anitric-oxide synthase biosynthetic process +
                                                is-apoly(3-hydroxyalkanoate) biosynthetic process +
                                                is-apoly(hydroxyalkanoate) biosynthetic process +
                                                is-apolyamine biosynthetic process +
                                                is-apolysaccharide biosynthetic process +
                                                positively-regulatespositive regulation of macromolecule biosynthetic process +
                                                part-ofprosthetic group biosynthetic process +
                                                is-aprotoporphyrinogen IX biosynthetic process +
                                                is-areceptor biosynthetic process +
                                                regulatesregulation of macromolecule biosynthetic process +
                                                is-aRNA biosynthetic process +
                                                is-aS100 alpha biosynthetic process
                                                is-aS100 beta biosynthetic process
                                                is-asuberin biosynthetic process
                                                is-atetrahydrofolylpolyglutamate biosynthetic process
                                                is-athymidylate synthase biosynthetic process +
                                                is-auroporphyrinogen III biosynthetic process +
                                                is-aviral protein biosynthetic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-acollagen metabolic process
                                                        is-acollagen biosynthetic process [GO:0032964] (31 genes, 34 annotations)
                                                                negatively-regulatesnegative regulation of collagen biosynthetic process
                                                                positively-regulatespositive regulation of collagen biosynthetic process
                                                                regulatesregulation of collagen biosynthetic process +
                                                        is-acollagen catabolic process +
                                                        negatively-regulatesnegative regulation of collagen metabolic process +
                                                        positively-regulatespositive regulation of collagen metabolic process +
                                                        regulatesregulation of collagen metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance biosynthetic process
                                        is-amacromolecule biosynthetic process
                                                is-aaminoglycan biosynthetic process +
                                                is-aamylopectin biosynthetic process
                                                is-abiotin carboxyl carrier protein biosynthetic process
                                                is-acellular macromolecule biosynthetic process +
                                                is-acollagen biosynthetic process [GO:0032964] (31 genes, 34 annotations)
                                                        negatively-regulatesnegative regulation of collagen biosynthetic process
                                                        positively-regulatespositive regulation of collagen biosynthetic process
                                                        regulatesregulation of collagen biosynthetic process +
                                                is-acutin biosynthetic process +
                                                is-aemericellamide biosynthetic process +
                                                is-aenniatin biosynthetic process
                                                is-aenterobactin biosynthetic process
                                                is-aimmunoglobulin biosynthetic process +
                                                is-aintegrin biosynthetic process +
                                                is-amacrolide biosynthetic process +
                                                is-aMHC class I biosynthetic process +
                                                is-aMHC class II biosynthetic process +
                                                negatively-regulatesnegative regulation of macromolecule biosynthetic process +
                                                is-anitric-oxide synthase biosynthetic process +
                                                is-apoly(3-hydroxyalkanoate) biosynthetic process +
                                                is-apoly(hydroxyalkanoate) biosynthetic process +
                                                is-apolyamine biosynthetic process +
                                                is-apolysaccharide biosynthetic process +
                                                positively-regulatespositive regulation of macromolecule biosynthetic process +
                                                part-ofprosthetic group biosynthetic process +
                                                is-aprotoporphyrinogen IX biosynthetic process +
                                                is-areceptor biosynthetic process +
                                                regulatesregulation of macromolecule biosynthetic process +
                                                is-aRNA biosynthetic process +
                                                is-aS100 alpha biosynthetic process
                                                is-aS100 beta biosynthetic process
                                                is-asuberin biosynthetic process
                                                is-atetrahydrofolylpolyglutamate biosynthetic process
                                                is-athymidylate synthase biosynthetic process +
                                                is-auroporphyrinogen III biosynthetic process +
                                                is-aviral protein biosynthetic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-acollagen metabolic process
                                                        is-acollagen biosynthetic process [GO:0032964] (31 genes, 34 annotations)
                                                                negatively-regulatesnegative regulation of collagen biosynthetic process
                                                                positively-regulatespositive regulation of collagen biosynthetic process
                                                                regulatesregulation of collagen biosynthetic process +
                                                        is-acollagen catabolic process +
                                                        negatively-regulatesnegative regulation of collagen metabolic process +
                                                        positively-regulatespositive regulation of collagen metabolic process +
                                                        regulatesregulation of collagen metabolic process +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-acollagen metabolic process
                                                        is-acollagen biosynthetic process [GO:0032964] (31 genes, 34 annotations)
                                                                negatively-regulatesnegative regulation of collagen biosynthetic process
                                                                positively-regulatespositive regulation of collagen biosynthetic process
                                                                regulatesregulation of collagen biosynthetic process +
                                                        is-acollagen catabolic process +
                                                        negatively-regulatesnegative regulation of collagen metabolic process +
                                                        positively-regulatespositive regulation of collagen metabolic process +
                                                        regulatesregulation of collagen metabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-acollagen metabolic process
                                                        is-acollagen biosynthetic process [GO:0032964] (31 genes, 34 annotations)
                                                                negatively-regulatesnegative regulation of collagen biosynthetic process
                                                                positively-regulatespositive regulation of collagen biosynthetic process
                                                                regulatesregulation of collagen biosynthetic process +
                                                        is-acollagen catabolic process +
                                                        negatively-regulatesnegative regulation of collagen metabolic process +
                                                        positively-regulatespositive regulation of collagen metabolic process +
                                                        regulatesregulation of collagen metabolic process +


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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory