Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACKR2
  • Mouse genes Ackr2
  • Rat genes Ackr2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ackr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019957	C-C chemokine binding	Ackr2	IPI	UniProtKB:P13501	Mouse	MGI:MGI:87663|PMID:9139699
Molecular Function	GO:0016493	C-C chemokine receptor activity	Ackr2	IDA		Mouse	PMID:9139699
Molecular Function	GO:0004950	chemokine receptor activity	ACKR2	IDA		Human	PMID:9364936
Molecular Function	GO:0005515	protein binding	ACKR2	IPI	UniProtKB:P11836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACKR2	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACKR2	IPI	UniProtKB:P52803	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACKR2	IPI	UniProtKB:Q0D2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACKR2	IPI	UniProtKB:Q9NRX6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACKR2	IPI	UniProtKB:Q9NTJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACKR2	IPI	UniProtKB:Q9UKG4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ackr2	IPI	PR:P10855	Mouse	PMID:9139699
Molecular Function	GO:0005044	scavenger receptor activity	ACKR2	IMP		Human	PMID:23633677
Cellular Component	GO:0005884	actin filament	ACKR2	IDA		Human	PMID:23633677
Cellular Component	GO:0005829	cytosol	ACKR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ACKR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	ACKR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ACKR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ACKR2	IDA		Human	PMID:23633677
Biological Process	GO:0007165	signal transduction	Ackr2	IDA		Mouse	PMID:9139699

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern