Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACE2
  • Mouse genes Ace2
  • Rat genes Ace2
  • Zfish genes ace2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ace2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004180	carboxypeptidase activity	ACE2	IDA		Human	PMID:10924499
Molecular Function	GO:0004180	carboxypeptidase activity	ACE2	IDA		Human	PMID:10969042
Molecular Function	GO:0004180	carboxypeptidase activity	ACE2	IDA		Human	PMID:15283675
Molecular Function	GO:0004180	carboxypeptidase activity	ACE2	IDA		Human	PMID:15380922
Molecular Function	GO:0004180	carboxypeptidase activity	ACE2	IDA		Human	PMID:18258853
Molecular Function	GO:0004180	carboxypeptidase activity	Ace2	IDA		Rat	PMID:22595130|RGD:9685456
Molecular Function	GO:0004175	endopeptidase activity	ACE2	IDA		Human	PMID:15283675
Molecular Function	GO:0042802	identical protein binding	ACE2	IPI	UniProtKB:Q9BYF1	Human	PMID:32275855
Molecular Function	GO:0042802	identical protein binding	ACE2	IPI	UniProtKB:Q9BYF1	Human	PMID:32678978
Molecular Function	GO:0042802	identical protein binding	ACE2	IPI	UniProtKB:Q9BYF1	Human	PMID:33262453
Molecular Function	GO:0042802	identical protein binding	ACE2	IPI	UniProtKB:Q9BYF1	Human	PMID:34867130
Molecular Function	GO:0004181	metallocarboxypeptidase activity	ACE2	EXP		Human	PMID:10924499
Molecular Function	GO:0004181	metallocarboxypeptidase activity	ACE2	EXP		Human	PMID:10969042
Molecular Function	GO:0004181	metallocarboxypeptidase activity	ACE2	EXP		Human	PMID:11815627
Molecular Function	GO:0008237	metallopeptidase activity	ACE2	IDA		Human	PMID:10924499
Molecular Function	GO:0008241	peptidyl-dipeptidase activity	ACE2	IDA		Human	PMID:10924499
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P01019:PRO_0000032457	Human	PMID:10969042
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P01042:PRO_0000006688	Human	PMID:10969042
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P30990:PRO_0000019524	Human	PMID:10969042
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P01019:PRO_0000032457	Human	PMID:11815627
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P01019:PRO_0000032458	Human	PMID:11815627
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P01042:PRO_0000006688	Human	PMID:11815627
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P30990:PRO_0000019524	Human	PMID:11815627
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594:PRO_0000037209	Human	PMID:14647384
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594:PRO_0000037209	Human	PMID:15479853
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:15791205
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q5GDB5	Human	PMID:15791205
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:18343844
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q6Q1S2	Human	PMID:18343844
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:18931070
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q6Q1S2	Human	PMID:18931070
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q695T7	Human	PMID:19185582
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q6Q1S2	Human	PMID:19901337
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:O15393	Human	PMID:21068237
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:21411533
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q6Q1S2	Human	PMID:21411533
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:22291007
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P05556	Human	PMID:22523556
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:23486063
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:23831647
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:30102747
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594:PRO_0000037209	Human	PMID:30102747
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:30356097
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32075877
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:32075877
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32132184
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2:PRO_0000449647	Human	PMID:32132184
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q695T7	Human	PMID:32132184
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32155444
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:32155444
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32203189
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:32203189
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:A0A6B9WHD3	Human	PMID:32225175
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32225175
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:32225175
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32225176
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32275855
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:32275855
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32332765
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:32332765
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32376634
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:32376634
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32415260
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:32415260
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32437749
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q01523:PRO_0000417390	Human	PMID:32437749
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32607506
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32637958
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32678978
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32694201
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32699321
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32703906
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32753755
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32766577
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32917722
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32958580
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:32991842
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33077916
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33082294
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P05556,UniProtKB:P08648,UniProtKB:P0DTC2	Human	PMID:33102950
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33102950
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33125711
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33140034
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33243994
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33244168
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33262453
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33277323
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33343834
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:33343834
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33417835
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33420426
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33432067
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33432247
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q5T2W1	Human	PMID:33436498
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q96CW1	Human	PMID:33436498
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q96L92	Human	PMID:33436498
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q9Y566	Human	PMID:33436498
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P01019:PRO_0000032458	Human	PMID:33453855
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P01042:PRO_0000006688	Human	PMID:33453855
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33453855
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:33453855
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33493263
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33527085
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33621484
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:33621484
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33636719
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P01185,UniProtKB:P0DTC2	Human	PMID:33713620
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33727252
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33730597
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33738989
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33774672
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:33774672
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33784482
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P35247	Human	PMID:33784482
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33914735
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P11021	Human	PMID:33965375
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:33993052
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:A0A6G6A1M4	Human	PMID:34018203
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:A0A6M3G9R1	Human	PMID:34018203
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34018203
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34022142
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34023401
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:O60341	Human	PMID:34031383
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34031383
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P52293	Human	PMID:34031383
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34069441
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34105996
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34158856
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34168070
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:O14745	Human	PMID:34189428
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q5T2W1	Human	PMID:34189428
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q695T7	Human	PMID:34189428
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34240429
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34289344
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34341769
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q9H2X3	Human	PMID:34341769
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P05067:PRO_0000000092	Human	PMID:34360989
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2:PRO_0000449647	Human	PMID:34360989
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34385690
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34439781
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34453338
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34478710
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34487793
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34499924
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34531369
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:34531369
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34536797
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34543625
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34545316
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34615619
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P11021	Human	PMID:34615619
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34668773
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P59594	Human	PMID:34668773
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q6Q1S2	Human	PMID:34668773
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34698504
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34751595
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34818667
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:A0A6B9WHD3	Human	PMID:34824253
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34824253
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:O14745	Human	PMID:34835087
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q5T2W1	Human	PMID:34835087
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q96L92	Human	PMID:34835087
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q9Y566	Human	PMID:34835087
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34867130
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34873039
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:Q14416	Human	PMID:34903715
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34914928
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34930910
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:34964720
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P08670	Human	PMID:35078919
Molecular Function	GO:0005515	protein binding	ACE2	IPI	UniProtKB:P0DTC2	Human	PMID:35078919
Molecular Function	GO:0005515	protein binding	Ace2	IPI	UniProtKB:A0A6G6A1M4|UniProtKB:A0A6M3G9R1|UniProtKB:P0DTC2	Mouse	MGI:MGI:6810290|PMID:34018203
Molecular Function	GO:0005515	protein binding	Ace2	IPI	UniProtKB:Q9D687	Mouse	MGI:MGI:3838678|PMID:19185582
Molecular Function	GO:0005515	protein binding	Ace2	IPI	UniProtKB:P0DTC2	Mouse	MGI:MGI:6751425|PMID:34158856
Molecular Function	GO:0005515	protein binding	Ace2	IPI	UniProtKB:P59594	Rat	PMID:15791205|RGD:30309928
Molecular Function	GO:0005515	protein binding	Ace2	IPI	UniProtKB:A0A6G6A1M4	Rat	PMID:34018203|RGD:150521627
Molecular Function	GO:0005515	protein binding	Ace2	IPI	UniProtKB:A0A6M3G9R1	Rat	PMID:34018203|RGD:150521627
Molecular Function	GO:0005515	protein binding	Ace2	IPI	UniProtKB:P0DTC2	Rat	PMID:34018203|RGD:150521627
Molecular Function	GO:0001618	virus receptor activity	ACE2	IDA		Human	PMID:16051304
Molecular Function	GO:0001618	virus receptor activity	ACE2	IDA		Human	PMID:18343844
Molecular Function	GO:0001618	virus receptor activity	ACE2	IMP		Human	PMID:24227843
Molecular Function	GO:0001618	virus receptor activity	ACE2	IDA		Human	PMID:33000221
Molecular Function	GO:0001618	virus receptor activity	ACE2	IDA		Human	PMID:33082294
Molecular Function	GO:0001618	virus receptor activity	ACE2	IDA		Human	PMID:33163980
Molecular Function	GO:0001618	virus receptor activity	ACE2	IDA		Human	PMID:33713620
Cellular Component	GO:0016324	apical plasma membrane	ACE2	IDA		Human	PMID:25534429
Cellular Component	GO:0031526	brush border membrane	ACE2	IDA		Human	PMID:25534429
Cellular Component	GO:0031526	brush border membrane	Ace2	IDA		Mouse	MGI:MGI:3838678|PMID:19185582
Cellular Component	GO:0009986	cell surface	ACE2	IDA		Human	PMID:18343844
Cellular Component	GO:0009986	cell surface	ACE2	IDA		Human	PMID:24227843
Cellular Component	GO:0005737	cytoplasm	Ace2	IDA		Mouse	MGI:MGI:5582870|PMID:23535237
Cellular Component	GO:0070062	extracellular exosome	ACE2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ACE2	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	ACE2	IDA		Human	PMID:10969042
Cellular Component	GO:0005576	extracellular region	ACE2	IDA		Human	PMID:33713620
Cellular Component	GO:0005615	extracellular space	ACE2	IDA		Human	PMID:18258853
Cellular Component	GO:0005615	extracellular space	Ace2	IDA		Rat	PMID:18223026|RGD:9685440
Cellular Component	GO:0016020	membrane	Ace2	IDA		Rat	PMID:15231706|RGD:2313801
Cellular Component	GO:0005886	plasma membrane	ACE2	IDA		Human	PMID:33163980
Cellular Component	GO:0005886	plasma membrane	ACE2	IDA		Human	PMID:21068237
Cellular Component	GO:0005886	plasma membrane	Ace2	IDA		Mouse	MGI:MGI:5582870|PMID:23535237
Biological Process	GO:0003051	angiotensin-mediated drinking behavior	ACE2	IMP		Human	PMID:18258853
Biological Process	GO:0060135	maternal process involved in female pregnancy	Ace2	IEP		Rat	PMID:17977916|RGD:8548898
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Ace2	IMP		Rat	PMID:20703229|RGD:9685431
Biological Process	GO:2000272	negative regulation of signaling receptor activity	ACE2	IMP		Human	PMID:18258853
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	Ace2	IMP		Rat	PMID:20703229|RGD:9685431
Biological Process	GO:0051957	positive regulation of amino acid transport	ACE2	IMP		Human	PMID:19185582
Biological Process	GO:0060452	positive regulation of cardiac muscle contraction	Ace2	IMP		Mouse	MGI:MGI:2181229|PMID:12075344
Biological Process	GO:1903598	positive regulation of gap junction assembly	ACE2	IMP		Human	PMID:12967627
Biological Process	GO:1905737	positive regulation of L-proline import across plasma membrane	ACE2	IGI	UniProtKB:Q9NP91	Human	PMID:25534429
Biological Process	GO:0046813	receptor-mediated virion attachment to host cell	ACE2	IDA		Human	PMID:18343844
Biological Process	GO:0046813	receptor-mediated virion attachment to host cell	ACE2	IDA		Human	PMID:32221306
Biological Process	GO:1903779	regulation of cardiac conduction	ACE2	IMP		Human	PMID:12967627
Biological Process	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	ACE2	IMP		Human	PMID:18258853
Biological Process	GO:0022898	regulation of transmembrane transporter activity	ACE2	IGI	UniProtKB:Q9NP91	Human	PMID:25534429
Biological Process	GO:0015827	tryptophan transport	Ace2	IMP		Mouse	MGI:MGI:5433234|PMID:22837003
Biological Process	GO:0046718	viral entry into host cell	ACE2	IDA		Human	PMID:33163980
Biological Process	GO:0046718	viral entry into host cell	ACE2	IDA		Human	PMID:16051304
Biological Process	GO:0046718	viral entry into host cell	ACE2	IDA		Human	PMID:32221306
Biological Process	GO:0046718	viral entry into host cell	ACE2	IDA		Human	PMID:33000221
Biological Process	GO:0046718	viral entry into host cell	ACE2	IDA		Human	PMID:33082294
Biological Process	GO:0046718	viral entry into host cell	ACE2	IDA		Human	PMID:33713620

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern