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Disease Ontology Browser
Lynch syndrome (DOID:3883)
Alliance: disease page
Synonyms: Hereditary Defective Mismatch Repair syndrome; Hereditary non-polyposis colon cancer; Hereditary non-polyposis colon cancer syndrome; Hereditary non-polyposis colorectal cancer; Hereditary non-polyposis colorectal cancer syndrome; Hereditary nonpolyposis colon cancer; Hereditary nonpolyposis colon cancer syndrome; hereditary nonpolyposis colorectal cancer; Hereditary nonpolyposis colorectal cancer syndrome; hereditary nonpolyposis colorectal neoplasm; HNPCC
Alt IDs: DOID:0050586, DOID:3040, MESH:D003123, NCI:C8494, OMIM:PS120435, ORDO:144, UMLS_CUI:C0009405, UMLS_CUI:C4552100
Definition: A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.

Disease References using Mouse Models (5)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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