Lynch syndrome (DOID:3883)
Alliance: disease page
Synonyms: COCA 1; Hereditary Defective Mismatch Repair syndrome; Hereditary non-polyposis colon cancer; Hereditary non-polyposis colon cancer syndrome; Hereditary non-polyposis colorectal cancer; Hereditary non-polyposis colorectal cancer syndrome; Hereditary nonpolyposis colon cancer; Hereditary nonpolyposis colon cancer syndrome; hereditary nonpolyposis colorectal cancer; Hereditary nonpolyposis colorectal cancer syndrome; hereditary nonpolyposis colorectal neoplasm; HNPCC - hereditary nonpolyposis colon cancer
Alt IDs: DOID:0050586, DOID:3040, MESH:D003123, NCI:C120083, OMIM:PS120435, ORDO:144, UMLS_CUI:C0009405, UMLS_CUI:C1333990
Definition: A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.