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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kitl+
wild type
MGI:1857738
Summary 56 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		KitlSl-21J/Kitl+ B10.BR H2k H2-T18a/SgSnJ-KitlSl-21J/GrsrJ MGI:3639041
ht2
 		KitlSl-t/Kitl+ B6.Cg-KitlSl-t MGI:4879105
ht3
 		KitlSl-23J/Kitl+ B6Smn(C3)-KitlSl-23J/J MGI:3711714
ht4
 		Kitltm1.1Sjm/Kitl+ BKa.129S6-Kitltm1.1Sjm MGI:5306346
ht5
 		KitlSl-28R/Kitl+ C3.101Rl-KitlSl-28R MGI:3794426
ht6
 		KitlSl-30R/Kitl+ C3.101Rl-KitlSl-30R MGI:3794428
ht7
 		KitlSl-42R/Kitl+ C3.101Rl-KitlSl-42R MGI:3794429
ht8
 		KitlSl-39R/Kitl+ C3.B10Rl-KitlSl-39R MGI:3794432
ht9
 		KitlSl-18R/Kitl+ C3.Cg-KitlSl-18R MGI:2652992
ht10
 		KitlSl-5R/Kitl+ C3.Cg-KitlSl-5R MGI:2652977
ht11
 		KitlSl-gb/Kitl+ C3.Cg-KitlSl-gb MGI:3794438
ht12
 		KitlSl-d/Kitl+ C3.D2-KitlSl-d MGI:3794435
ht13
 		KitlSl-J/Kitl+ C3HeB/FeHu-KitlSl-J MGI:3833576
ht14
 		KitlSl-17H/Kitl+ C3H/HeH-KitlSl-17H MGI:3054440
ht15
 		KitlSl-22R/Kitl+ C3H-KitlSl-22R MGI:3794420
ht16
 		KitlSl-31R/Kitl+ C3H-KitlSl-31R MGI:3794421
ht17
 		KitlSl-36R/Kitl+ C3H-KitlSl-36R MGI:3794424
ht18
 		KitlSl-20J/Kitl+ C57BL/6J-KitlSl-20J/J MGI:2682008
ht19
 		KitlSl-22J/Kitl+ C57BL/6J-KitlSl-22J/GrsrJ MGI:3697524
ht20
 		KitlSl-d/Kitl+ either: DBA/2J or (C57BL/6 x DBA/2)F1 MGI:2387002
ht21
 		KitlSl-pan/Kitl+ either: (involves: C3H/HeJ * C57BL/6J) or (involves: C3H/HeN * C57BL/6J) MGI:3045104
ht22
 		KitlSl-con/Kitl+ either: (involves: C3H/HeJ) or (involves: C3H/HeN) MGI:3045114
ht23
 		KitlSl/Kitl+ either: (involves: C3H * WC) or (involves: C3H * C57BL/6 * DBA/2J * WC) MGI:3690621
ht24
 		KitlSl-d/Kitl+ either: (involves: C57BL/6 * DBA/2J) or (involves: C3H * C57BL/6 * DBA/2J * WC) MGI:3690620
ht25
 		KitlSl-18H/Kitl+ involves: 101/H * C3H/HeH MGI:3778060
ht26
 		KitlSl-34H/Kitl+ involves: 101/H * C3H/HeH MGI:5313583
ht27
 		KitlSl-29H/Kitl+ involves: 101/H * C3H/HeH MGI:5314358
ht28
 		KitlSl-10H/Kitl+ involves: 101/H * C3H/HeH MGI:4838402
ht29
 		KitlSl-13H/Kitl+ involves: 101/H * C3H/HeH MGI:5301945
ht30
 		KitlSl-15H/Kitl+ involves: 101/H * C3H/HeH MGI:5301947
ht31
 		KitlSl-26H/Kitl+ involves: 101/H * C3H/HeH MGI:5301951
ht32
 		KitlSl-30H/Kitl+ involves: 101/H * C3H/HeH MGI:5301954
ht33
 		KitlSl-31H/Kitl+ involves: 101/H * C3H/HeH MGI:5301957
ht34
 		KitlSl-33H/Kitl+ involves: 101/H * C3H/HeH MGI:5301958
ht35
 		KitlSl-3R/Kitl+ involves: 101/Rl * C3H/Rl MGI:3719392
ht36
 		KitlSl-12R/Kitl+ involves: 101/Rl * C3H/Rl MGI:3719396
ht37
 		KitlSl-2Neu/Kitl+ involves: 102/El * C3H/El MGI:3819125
ht38
 		KitlSl-1Neu/Kitl+ involves: 102/El * C3H/El MGI:3819123
ht39
 		KitlSl-3Neu/Kitl+ involves: 102/El * C3H/El MGI:3819128
ht40
 		KitlSl-J/Kitl+ involves: 129 MGI:3833649
ht41
 		KitlSl-16J/Kitl+ involves: 129 * Lipari MGI:5050105
ht42
 		Kitltm3.1Pbes/Kitl+ involves: 129S1/Sv * C57BL/6J * FVB/N MGI:4430872
ht43
 		KitlSl/Kitl+ involves: 129/Sv * C3H MGI:3690647
ht44
 		Kitltm2.2Sjm/Kitl+ involves: BALB/cJ * C57BL/6 * C57BL/Ka * SJL MGI:5306349
ht45
 		KitlSl/Kitl+ involves: C3H MGI:2387145
ht46
 		KitlSl-27H/Kitl+ involves: C3H/HeH MGI:5301952
ht47
 		KitlSl-21H/Kitl+ involves: C3H/HeH MGI:5301949
ht48
 		KitlSl-so/Kitl+ involves: C57BL/6 MGI:5142485
ht49
 		KitlSl-m/Kitl+ involves: C57BL/6 MGI:5142489
ht50
 		KitlM1Bao/Kitl+ involves: C57BL/6J MGI:4839550
ht51
 		KitlSl-d/Kitl+ involves: DBA/2J MGI:4431038
ht52
 		KitlSl-Clo/Kitl+ Not Specified MGI:5142523
cx53
 		KitlSl-18H/Kitl+
X/SryAKR/J 		involves: AKR/J * C57BL/6J MGI:3778817
cx54
 		KitlSl/Kitl+
Tg(PGK1-KITLG*220)441Daw/0 		involves: C3H MGI:3817636
cx55
 		KitlSl-d/Kitl+
rs/rs 		involves: C3H/HeJ * DBA/2J MGI:4431074
cx56
 		KitlSl-d/Kitl+
Ph/Ph+ 		involves: C57BL/Gr * DBA/2J MGI:4431080


Genotype
MGI:3639041
ht1
Allelic
Composition		 KitlSl-21J/Kitl+
Genetic
Background		 B10.BR H2k H2-T18a/SgSnJ-KitlSl-21J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-21J mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Lighter coat color in KitlSl-21J/Kitl+ mice (in the back) compared to wild-type sibling (front)

pigmentation
belly spot ( J:107116 )
• variable size
abnormal foot pigmentation ( J:107116 )
• lightens ears, tail and feet

integument
belly spot ( J:107116 )
• variable size
abnormal foot pigmentation ( J:107116 )
• lightens ears, tail and feet

craniofacial

hearing/vestibular/ear

limbs/digits/tail

growth/size/body
decreased ear pigmentation ( J:107116 )




Genotype
MGI:4879105
ht2
Allelic
Composition		 KitlSl-t/Kitl+
Genetic
Background		 B6.Cg-KitlSl-t
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-t mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:81273 )
• slightly diluted color

pigmentation
diluted coat color ( J:81273 )
• slightly diluted color

limbs/digits/tail




Genotype
MGI:3711714
ht3
Allelic
Composition		 KitlSl-23J/Kitl+
Genetic
Background		 B6Smn(C3)-KitlSl-23J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-23J mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

The bellies of two mutant KitlSl-23J/Kitl+ (right and left) and a control littermate (center) showing white belly spot on the heterozygote on the left

pigmentation
belly spot ( J:121474 )
• the degree of spotting varies greatly from mouse to mouse

integument
belly spot ( J:121474 )
• the degree of spotting varies greatly from mouse to mouse




Genotype
MGI:5306346
ht4
Allelic
Composition		 Kitltm1.1Sjm/Kitl+
Genetic
Background		 BKa.129S6-Kitltm1.1Sjm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kitltm1.1Sjm mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
liver hypoplasia ( J:180431 )
• 2-fold




Genotype
MGI:3794426
ht5
Allelic
Composition		 KitlSl-28R/Kitl+
Genetic
Background		 C3.101Rl-KitlSl-28R
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-28R mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
macrocytic anemia ( J:79293 )
• mild at birth
increased mean corpuscular hemoglobin ( J:79293 )
• significantly increased compared to wild-type at P24-25
increased mean corpuscular volume ( J:79293 )
• significantly increased compared to wild-type at P24-25

pigmentation

integument




Genotype
MGI:3794428
ht6
Allelic
Composition		 KitlSl-30R/Kitl+
Genetic
Background		 C3.101Rl-KitlSl-30R
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-30R mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
macrocytic anemia ( J:79293 )
• mild at birth
decreased hematocrit ( J:79293 )
• significantly lower than wild-type at P24-25
increased mean corpuscular hemoglobin ( J:79293 )
• significantly increased compared to wild-type at P24-25
increased mean corpuscular volume ( J:79293 )
• significantly increased compared to wild-type at P24-25

pigmentation

integument




Genotype
MGI:3794429
ht7
Allelic
Composition		 KitlSl-42R/Kitl+
Genetic
Background		 C3.101Rl-KitlSl-42R
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-42R mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
macrocytic anemia ( J:79293 )
• mild at birth
decreased hematocrit ( J:79293 )
• significantly lower than wild-type at P24-25
increased mean corpuscular hemoglobin ( J:79293 )
• significantly increased compared to wild-type at P24-25
increased mean corpuscular volume ( J:79293 )
• significantly increased compared to wild-type at P24-25

pigmentation

integument




Genotype
MGI:3794432
ht8
Allelic
Composition		 KitlSl-39R/Kitl+
Genetic
Background		 C3.B10Rl-KitlSl-39R
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-39R mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
macrocytic anemia ( J:79293 )
• mild at birth
low mean erythrocyte cell number ( J:79293 )
• at P1, mean red blood cell (RBC) counts are not different from KitlSl-d / KitlSl-gb compound heterozygotes (2.9 x 109 cells/ml; 4.1 x 109 cells/ml in wild-type mice)
increased mean corpuscular hemoglobin ( J:79293 )
• significantly increased compared to wild-type at P24-25
increased mean corpuscular volume ( J:79293 )
• significantly increased compared to wild-type at P24-25

pigmentation

integument




Genotype
MGI:2652992
ht9
Allelic
Composition		 KitlSl-18R/Kitl+
Genetic
Background		 C3.Cg-KitlSl-18R
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-18R mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased erythrocyte cell number ( J:82263 )
• at P1, mean peripheral RBC counts are 80% of wild-type values, suggesting a slightly milder anemia than that seen in age-matched KitlSl-gb heterozygotes (71% of wild-type values)




Genotype
MGI:2652977
ht10
Allelic
Composition		 KitlSl-5R/Kitl+
Genetic
Background		 C3.Cg-KitlSl-5R
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-5R mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased erythrocyte cell number ( J:82263 )
• at P1, mean peripheral RBC counts are 80% of wild-type values, suggesting a slightly milder anemia than that seen in age-matched KitlSl-gb heterozygotes (71% of wild-type values)




Genotype
MGI:3794438
ht11
Allelic
Composition		 KitlSl-gb/Kitl+
Genetic
Background		 C3.Cg-KitlSl-gb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-gb mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
macrocytic anemia ( J:79293 )
• mild at birth
increased mean corpuscular hemoglobin ( J:79293 )
• significantly increased compared to wild-type at P24-25
increased mean corpuscular volume ( J:79293 )
• significantly increased compared to wild-type at P24-25

pigmentation

integument




Genotype
MGI:3794435
ht12
Allelic
Composition		 KitlSl-d/Kitl+
Genetic
Background		 C3.D2-KitlSl-d
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-d mutation (3 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
macrocytic anemia ( J:79293 )
• mild at birth
low mean erythrocyte cell number ( J:79293 )
• at P1, mean red blood cell (RBC) counts are not different from KitlSl-d / KitlSl-gb compound heterozygotes (2.9 x 109 cells/ml; 4.1 x 109 cells/ml in wild-type mice)
increased mean corpuscular hemoglobin ( J:79293 )
• significantly increased compared to wild-type at P24-25
increased mean corpuscular volume ( J:79293 )
• significantly increased compared to wild-type at P24-25

pigmentation

integument




Genotype
MGI:3833576
ht13
Allelic
Composition		 KitlSl-J/Kitl+
Genetic
Background		 C3HeB/FeHu-KitlSl-J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-J mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:145144 )
• lightened coat color compared to normal and the belly is very light
white spotting ( J:145144 )
• the feet and tail tip are white
• a white dot on the head is characteristic
belly spot ( J:145144 )
• a mid-ventral white streak becomes more apparent with age

integument
diluted coat color ( J:145144 )
• lightened coat color compared to normal and the belly is very light
white spotting ( J:145144 )
• the feet and tail tip are white
• a white dot on the head is characteristic
belly spot ( J:145144 )
• a mid-ventral white streak becomes more apparent with age




Genotype
MGI:3054440
ht14
Allelic
Composition		 KitlSl-17H/Kitl+
Genetic
Background		 C3H/HeH-KitlSl-17H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-17H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:24739 )
• unlike many other Kitl alleles, the coat of this genotype is only rarely lighter than wild-type
irregular coat pigmentation ( J:24739 )
• small pigmented areas occasionally on hips and base of shoulders
white spotting ( J:24739 )
• on tail and/or feet
belly spot ( J:24739 )
• occasional
head spot ( J:24739 )
• occasional

reproductive system
decreased primordial germ cell number ( J:2880 )
• at E11.5, PGC numbers are reduced to ~64-66% of wild-type levels; both sexes are equally affected
• in two E12.5 female heterozygotes, PGC numbers are reduced to ~46% of wild-type levels

integument
diluted coat color ( J:24739 )
• unlike many other Kitl alleles, the coat of this genotype is only rarely lighter than wild-type
irregular coat pigmentation ( J:24739 )
• small pigmented areas occasionally on hips and base of shoulders
white spotting ( J:24739 )
• on tail and/or feet
belly spot ( J:24739 )
• occasional
head spot ( J:24739 )
• occasional

cellular
decreased primordial germ cell number ( J:2880 )
• at E11.5, PGC numbers are reduced to ~64-66% of wild-type levels; both sexes are equally affected
• in two E12.5 female heterozygotes, PGC numbers are reduced to ~46% of wild-type levels




Genotype
MGI:3794420
ht15
Allelic
Composition		 KitlSl-22R/Kitl+
Genetic
Background		 C3H-KitlSl-22R
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-22R mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:79293 )
N
• at P1, mean red blood cell (RBC) counts are not different from wild-type mean (4.1 x 109 cells/ml)
macrocytic anemia ( J:79293 )
• mild at birth
increased mean corpuscular hemoglobin ( J:79293 )
• significantly increased compared to wild-type at P24-25
increased mean corpuscular volume ( J:79293 )
• significantly increased compared to wild-type at P24-25

pigmentation

integument




Genotype
MGI:3794421
ht16
Allelic
Composition		 KitlSl-31R/Kitl+
Genetic
Background		 C3H-KitlSl-31R
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-31R mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
macrocytic anemia ( J:79293 )
• mild at birth
increased mean corpuscular hemoglobin ( J:79293 )
• significantly increased compared to wild-type at P24-25
increased mean corpuscular volume ( J:79293 )
• significantly increased compared to wild-type at P24-25

pigmentation

integument




Genotype
MGI:3794424
ht17
Allelic
Composition		 KitlSl-36R/Kitl+
Genetic
Background		 C3H-KitlSl-36R
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-36R mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
macrocytic anemia ( J:79293 )
• mild at birth
low mean erythrocyte cell number ( J:79293 )
• at P1, mean red blood cell (RBC) counts are not different from KitlSl-d / KitlSl-gb compound heterozygotes (2.9 x 109 cells/ml; 4.1 x 109 cells/ml in wild-type mice)
increased mean corpuscular hemoglobin ( J:79293 )
• significantly increased compared to wild-type at P24-25
increased mean corpuscular volume ( J:79293 )
• significantly increased compared to wild-type at P24-25

pigmentation

integument




Genotype
MGI:2682008
ht18
Allelic
Composition		 KitlSl-20J/Kitl+
Genetic
Background		 C57BL/6J-KitlSl-20J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-20J mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
belly spot ( J:86436 )
• heterozygous mice have either a white belly spot or dilute ventral pigmentation

integument
belly spot ( J:86436 )
• heterozygous mice have either a white belly spot or dilute ventral pigmentation




Genotype
MGI:3697524
ht19
Allelic
Composition		 KitlSl-22J/Kitl+
Genetic
Background		 C57BL/6J-KitlSl-22J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-22J mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Diluted coat color and lighter ears, feet, and tail in KitlSl-22J/Kitl+ mice (right) compared to littermate control (left)

pigmentation
belly spot ( J:117733 )
• variable size
abnormal foot pigmentation ( J:117733 )
• lighter than normal ears, tail, and feet
abnormal retina pigmentation ( J:117733 )
• peripheral retina in the one animal assessed shows areas of pigment loss

vision/eye
vision/eye phenotype ( J:117733 )
N
• ERG test on one mutant was normal
abnormal retina pigmentation ( J:117733 )
• peripheral retina in the one animal assessed shows areas of pigment loss

hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:117733 )
N
• ABR testing normal

integument
belly spot ( J:117733 )
• variable size
abnormal foot pigmentation ( J:117733 )
• lighter than normal ears, tail, and feet

craniofacial

limbs/digits/tail

growth/size/body
decreased ear pigmentation ( J:117733 )




Genotype
MGI:2387002
ht20
Allelic
Composition		 KitlSl-d/Kitl+
Genetic
Background		 either: DBA/2J or (C57BL/6 x DBA/2)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-d mutation (3 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:13392 )
• heterozygotes have a slightly diluted coat color

integument
diluted coat color ( J:13392 )
• heterozygotes have a slightly diluted coat color




Genotype
MGI:3045104
ht21
Allelic
Composition		 KitlSl-pan/Kitl+
Genetic
Background		 either: (involves: C3H/HeJ * C57BL/6J) or (involves: C3H/HeN * C57BL/6J)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-pan mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation

reproductive system
reproductive system phenotype ( J:23593 )
N
• both males and females were fertile
decreased primordial germ cell number ( J:23593 )
• the number of primordial germ cells (PGCs) in females was reduced to ~55% that of wild-type females at E11.5
• the number of PGCs in males was reduced to ~45% that of wild-type males at E11.5

integument

cellular
decreased primordial germ cell number ( J:23593 )
• the number of primordial germ cells (PGCs) in females was reduced to ~55% that of wild-type females at E11.5
• the number of PGCs in males was reduced to ~45% that of wild-type males at E11.5




Genotype
MGI:3045114
ht22
Allelic
Composition		 KitlSl-con/Kitl+
Genetic
Background		 either: (involves: C3H/HeJ) or (involves: C3H/HeN)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-con mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
hyperpigmentation ( J:23593 )
• hyperpigmentation of the genital papillae

reproductive system
reproductive system phenotype ( J:23593 )
N
• both males and females were fertile
abnormal ovarian folliculogenesis ( J:23593 )
• initiation and maintenance of follicles is disrupted

endocrine/exocrine glands
abnormal ovarian folliculogenesis ( J:23593 )
• initiation and maintenance of follicles is disrupted

integument

cellular




Genotype
MGI:3690621
ht23
Allelic
Composition		 KitlSl/Kitl+
Genetic
Background		 either: (involves: C3H * WC) or (involves: C3H * C57BL/6 * DBA/2J * WC)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl mutation (3 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
anemia ( J:6084 )
• mice are slightly anemic
decreased mast cell number ( J:6084 )
• heterozygotes have decreased mast cell numbers in dorsal skin compared to wild-type

immune system
decreased mast cell number ( J:6084 )
• heterozygotes have decreased mast cell numbers in dorsal skin compared to wild-type




Genotype
MGI:3690620
ht24
Allelic
Composition		 KitlSl-d/Kitl+
Genetic
Background		 either: (involves: C57BL/6 * DBA/2J) or (involves: C3H * C57BL/6 * DBA/2J * WC)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-d mutation (3 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
anemia ( J:6084 )
• mice are slightly anemic
decreased mast cell number ( J:6084 )
• heterozygotes have decreased mast cell numbers in dorsal skin compared to wild-type

immune system
decreased mast cell number ( J:6084 )
• heterozygotes have decreased mast cell numbers in dorsal skin compared to wild-type




Genotype
MGI:3778060
ht25
Allelic
Composition		 KitlSl-18H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-18H mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:18280 )
• small, pale young seen at birth likely comprise the 40% loss of heterozygotes from heterozygous matings

pigmentation
diluted coat color ( J:18280 )
• greyish coat
head blaze ( J:18280 )
• in combination with KitlSl-con there is a prominent white head blaze
white spotting ( J:18280 )
• head spotting and occasional nose and belly spotting
belly spot ( J:18280 )
• occasional belly spot
hypopigmentation ( J:18280 )
• ears and tail are pale

hematopoietic system
anemia ( J:18280 )
• pale offspring are presumed to be slightly anemic

integument
diluted coat color ( J:18280 )
• greyish coat
head blaze ( J:18280 )
• in combination with KitlSl-con there is a prominent white head blaze
white spotting ( J:18280 )
• head spotting and occasional nose and belly spotting
belly spot ( J:18280 )
• occasional belly spot




Genotype
MGI:5313583
ht26
Allelic
Composition		 KitlSl-34H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-34H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
white spotting ( J:44592 )
• variable belly spot and/or head blaze

pigmentation
white spotting ( J:44592 )
• variable belly spot and/or head blaze




Genotype
MGI:5314358
ht27
Allelic
Composition		 KitlSl-29H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-29H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument

pigmentation




Genotype
MGI:4838402
ht28
Allelic
Composition		 KitlSl-10H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-10H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:14014 )
• the coat is lighter than expected for the genotype
white spotting ( J:14014 )
• there is an occasional head-dot and/or white tail-tip
abnormal foot pigmentation ( J:14014 )
• feet are lighter than expected

integument
diluted coat color ( J:14014 )
• the coat is lighter than expected for the genotype
white spotting ( J:14014 )
• there is an occasional head-dot and/or white tail-tip
abnormal foot pigmentation ( J:14014 )
• feet are lighter than expected




Genotype
MGI:5301945
ht29
Allelic
Composition		 KitlSl-13H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-13H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/hair pigmentation ( J:179353 )
• greyish coat, occasional head and belly spot, half white feet and tail
abnormal tail hair pigmentation ( J:179353 )
• half white feet and tail
belly spot ( J:179353 )
• occasional
head spot ( J:179353 )
• occasional

pigmentation
abnormal coat/hair pigmentation ( J:179353 )
• greyish coat, occasional head and belly spot, half white feet and tail
abnormal tail hair pigmentation ( J:179353 )
• half white feet and tail
belly spot ( J:179353 )
• occasional
head spot ( J:179353 )
• occasional




Genotype
MGI:5301947
ht30
Allelic
Composition		 KitlSl-15H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-15H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/hair pigmentation ( J:179353 )
• greyish coat, occasional head and belly spot, half white feet and tail
abnormal tail hair pigmentation ( J:179353 )
• half white feet and tail
belly spot ( J:179353 )
• occasional
head spot ( J:179353 )
• occasional

pigmentation
abnormal coat/hair pigmentation ( J:179353 )
• greyish coat, occasional head and belly spot, half white feet and tail
abnormal tail hair pigmentation ( J:179353 )
• half white feet and tail
belly spot ( J:179353 )
• occasional
head spot ( J:179353 )
• occasional




Genotype
MGI:5301951
ht31
Allelic
Composition		 KitlSl-26H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-26H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/hair pigmentation ( J:179353 )
• head spot, pale coat, belly and feet

pigmentation
abnormal coat/hair pigmentation ( J:179353 )
• head spot, pale coat, belly and feet




Genotype
MGI:5301954
ht32
Allelic
Composition		 KitlSl-30H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-30H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal tail hair pigmentation ( J:179353 )
• light coloured coat and pale tail
diluted coat color ( J:179353 )
• light coloured coat and pale tail

pigmentation
abnormal tail hair pigmentation ( J:179353 )
• light coloured coat and pale tail
diluted coat color ( J:179353 )
• light coloured coat and pale tail




Genotype
MGI:5301957
ht33
Allelic
Composition		 KitlSl-31H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-31H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/hair pigmentation ( J:179353 )
• grey coat, pale feet and belly, belly spot

pigmentation
abnormal coat/hair pigmentation ( J:179353 )
• grey coat, pale feet and belly, belly spot




Genotype
MGI:5301958
ht34
Allelic
Composition		 KitlSl-33H/Kitl+
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-33H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/hair pigmentation ( J:179353 )
• greyish coat, pale feet and tail

pigmentation
abnormal coat/hair pigmentation ( J:179353 )
• greyish coat, pale feet and tail




Genotype
MGI:3719392
ht35
Allelic
Composition		 KitlSl-3R/Kitl+
Genetic
Background		 involves: 101/Rl * C3H/Rl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-3R mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:100221 )
• hair pigment reduced or altered all over; pigmentation is similar to KitlSl/+

integument
diluted coat color ( J:100221 )
• hair pigment reduced or altered all over; pigmentation is similar to KitlSl/+




Genotype
MGI:3719396
ht36
Allelic
Composition		 KitlSl-12R/Kitl+
Genetic
Background		 involves: 101/Rl * C3H/Rl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-12R mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:100221 )
• hair pigment reduced or altered all over; pigmentation is similar to KitlSl/+

reproductive system

integument
diluted coat color ( J:100221 )
• hair pigment reduced or altered all over; pigmentation is similar to KitlSl/+




Genotype
MGI:3819125
ht37
Allelic
Composition		 KitlSl-2Neu/Kitl+
Genetic
Background		 involves: 102/El * C3H/El
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-2Neu mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:37172 )
• slight dilution of coat color
head spot ( J:37172 )
• occasional forehead spots

hematopoietic system

integument
diluted coat color ( J:37172 )
• slight dilution of coat color
head spot ( J:37172 )
• occasional forehead spots




Genotype
MGI:3819123
ht38
Allelic
Composition		 KitlSl-1Neu/Kitl+
Genetic
Background		 involves: 102/El * C3H/El
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-1Neu mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:37172 )
• reduced, grayish coat pigmentation is seen bothe ventrally and dorsally
belly spot ( J:37172 )
• seen occasionally
head spot ( J:37172 )
• seen occasionally

hematopoietic system

integument
diluted coat color ( J:37172 )
• reduced, grayish coat pigmentation is seen bothe ventrally and dorsally
belly spot ( J:37172 )
• seen occasionally
head spot ( J:37172 )
• seen occasionally




Genotype
MGI:3819128
ht39
Allelic
Composition		 KitlSl-3Neu/Kitl+
Genetic
Background		 involves: 102/El * C3H/El
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-3Neu mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:43966 )
• slightly grayish fur

integument
diluted coat color ( J:43966 )
• slightly grayish fur




Genotype
MGI:3833649
ht40
Allelic
Composition		 KitlSl-J/Kitl+
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-J mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased testicular teratoma incidence ( J:50508 )
• Background Sensitivity: tumor incidence is markedly increased in the presence of this allele
• Background Sensitivity: in the presence of this allele, appreciable differences are seen in the incidence of tumors among 129 sublines

endocrine/exocrine glands
increased testicular teratoma incidence ( J:50508 )
• Background Sensitivity: tumor incidence is markedly increased in the presence of this allele
• Background Sensitivity: in the presence of this allele, appreciable differences are seen in the incidence of tumors among 129 sublines

reproductive system
increased testicular teratoma incidence ( J:50508 )
• Background Sensitivity: tumor incidence is markedly increased in the presence of this allele
• Background Sensitivity: in the presence of this allele, appreciable differences are seen in the incidence of tumors among 129 sublines




Genotype
MGI:5050105
ht41
Allelic
Composition		 KitlSl-16J/Kitl+
Genetic
Background		 involves: 129 * Lipari
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-16J mutation (1 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:30778 )
• the coat is lighter than expectd for this genotype
white spotting ( J:30778 )
• variable but most likley on the head and/or vetrum

pigmentation
diluted coat color ( J:30778 )
• the coat is lighter than expectd for this genotype
white spotting ( J:30778 )
• variable but most likley on the head and/or vetrum




Genotype
MGI:4430872
ht42
Allelic
Composition		 Kitltm3.1Pbes/Kitl+
Genetic
Background		 involves: 129S1/Sv * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kitltm3.1Pbes mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
belly spot ( J:157170 )
• unaffected pigmentation except for a white belly spot

integument
belly spot ( J:157170 )
• unaffected pigmentation except for a white belly spot




Genotype
MGI:3690647
ht43
Allelic
Composition		 KitlSl/Kitl+
Genetic
Background		 involves: 129/Sv * C3H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl mutation (3 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor incidence ( J:50508 )
• male mice develop ~2-fold more tumors than controls
increased testicular teratoma incidence ( J:50508 )
• incidence is 6.92% compared to ~2.6% in controls
• tumors are predominantly in left testis (71%) vs right (27%) or bilateral (2%)
• percentage is greater in second and subsequent litters compared to first litter or in first litter of older females compared to young mothers

reproductive system
increased testicular teratoma incidence ( J:50508 )
• incidence is 6.92% compared to ~2.6% in controls
• tumors are predominantly in left testis (71%) vs right (27%) or bilateral (2%)
• percentage is greater in second and subsequent litters compared to first litter or in first litter of older females compared to young mothers

endocrine/exocrine glands
increased testicular teratoma incidence ( J:50508 )
• incidence is 6.92% compared to ~2.6% in controls
• tumors are predominantly in left testis (71%) vs right (27%) or bilateral (2%)
• percentage is greater in second and subsequent litters compared to first litter or in first litter of older females compared to young mothers




Genotype
MGI:5306349
ht44
Allelic
Composition		 Kitltm2.2Sjm/Kitl+
Genetic
Background		 involves: BALB/cJ * C57BL/6 * C57BL/Ka * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kitltm2.2Sjm mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system




Genotype
MGI:2387145
ht45
Allelic
Composition		 KitlSl/Kitl+
Genetic
Background		 involves: C3H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl mutation (3 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
decreased ear pigmentation ( J:3399 )
• mice have light ears
diluted coat color ( J:3399 , J:157170 )
• affected mice have overall dilution of coat color, more extreme on the belly than back (J:3399)
• reduced coat color (J:157170)
head blaze ( J:3399 )
• very occasionally mice have a white blaze between their eyes
belly spot ( J:3399 , J:157170 )
• most mice have a white spot on the belly (J:3399)
head spot ( J:3399 )
• most mice have a white spot on the belly
decreased foot pigmentation ( J:3399 )
• mice have light feet

hematopoietic system
anemia ( J:3399 )
• mice display less severe anemia than homozygotes
decreased erythrocyte cell number ( J:3399 )
• at 7-13 days of age, red blood cell counts are 20-30% lower than wild-type

hearing/vestibular/ear
decreased ear pigmentation ( J:3399 )
• mice have light ears

reproductive system
reproductive system phenotype ( J:3399 )
N
• heterozygotes are viable and fertile

craniofacial
decreased ear pigmentation ( J:3399 )
• mice have light ears

integument
decreased ear pigmentation ( J:3399 )
• mice have light ears
diluted coat color ( J:3399 , J:157170 )
• affected mice have overall dilution of coat color, more extreme on the belly than back (J:3399)
• reduced coat color (J:157170)
head blaze ( J:3399 )
• very occasionally mice have a white blaze between their eyes
belly spot ( J:3399 , J:157170 )
• most mice have a white spot on the belly (J:3399)
head spot ( J:3399 )
• most mice have a white spot on the belly
abnormal vibrissa morphology ( J:3399 )
• mice have light whiskers
pallor ( J:3399 )
• some pups after birth are pale compared to littermates
decreased foot pigmentation ( J:3399 )
• mice have light feet

growth/size/body
decreased ear pigmentation ( J:3399 )
• mice have light ears




Genotype
MGI:5301952
ht46
Allelic
Composition		 KitlSl-27H/Kitl+
Genetic
Background		 involves: C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-27H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/hair pigmentation ( J:179353 )
• head spot, light coat and belly, pale feet

pigmentation
abnormal coat/hair pigmentation ( J:179353 )
• head spot, light coat and belly, pale feet




Genotype
MGI:5301949
ht47
Allelic
Composition		 KitlSl-21H/Kitl+
Genetic
Background		 involves: C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-21H mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/hair pigmentation ( J:179353 )
• greyish coat, head and belly spot, white feet and tail
abnormal tail hair pigmentation ( J:179353 )
• white feet and tail

pigmentation
abnormal coat/hair pigmentation ( J:179353 )
• greyish coat, head and belly spot, white feet and tail
abnormal tail hair pigmentation ( J:179353 )
• white feet and tail




Genotype
MGI:5142485
ht48
Allelic
Composition		 KitlSl-so/Kitl+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-so mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal tail hair pigmentation ( J:13416 )
• the tail is "whitened"
diluted coat color ( J:13416 )
• the body coat color is somewhat diluted compared with the expected non-agouti black of the strain background

pigmentation
abnormal tail hair pigmentation ( J:13416 )
• the tail is "whitened"
diluted coat color ( J:13416 )
• the body coat color is somewhat diluted compared with the expected non-agouti black of the strain background




Genotype
MGI:5142489
ht49
Allelic
Composition		 KitlSl-m/Kitl+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-m mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument

pigmentation




Genotype
MGI:4839550
ht50
Allelic
Composition		 KitlM1Bao/Kitl+
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlM1Bao mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
white spotting ( J:164566 )
• white spotting at the distal ends of the four limbs

integument
white spotting ( J:164566 )
• white spotting at the distal ends of the four limbs




Genotype
MGI:4431038
ht51
Allelic
Composition		 KitlSl-d/Kitl+
Genetic
Background		 involves: DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-d mutation (3 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
macrocytic anemia ( J:125080 )
• mild macrocytic anemia

pigmentation
diluted coat color ( J:125080 )
• slightly diluted coat color is more noticeable on the belly

integument
diluted coat color ( J:125080 )
• slightly diluted coat color is more noticeable on the belly




Genotype
MGI:5142523
ht52
Allelic
Composition		 KitlSl-Clo/Kitl+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-Clo mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/hair pigmentation ( J:13613 )
• slightly lighter than wild-type

pigmentation
abnormal coat/hair pigmentation ( J:13613 )
• slightly lighter than wild-type




Genotype
MGI:3778817
cx53
Allelic
Composition		 KitlSl-18H/Kitl+
X/SryAKR/J
Genetic
Background		 involves: AKR/J * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-18H mutation (1 available); any Kitl mutation (92 available)
SryAKR/J mutation (6 available); any Sry mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
decreased testis weight ( J:133266 )
• Background Sensitivity: in the presence of SryAKR/J on a C57BL/6 background testes weight is less than normal

reproductive system
decreased testis weight ( J:133266 )
• Background Sensitivity: in the presence of SryAKR/J on a C57BL/6 background testes weight is less than normal




Genotype
MGI:3817636
cx54
Allelic
Composition		 KitlSl/Kitl+
Tg(PGK1-KITLG*220)441Daw/0
Genetic
Background		 involves: C3H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl mutation (3 available); any Kitl mutation (92 available)
Tg(PGK1-KITLG*220)441Daw mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
abnormal coat/hair pigmentation ( J:32600 )
• 18% of offspring show more severe pigment loss than either parental strain

hematopoietic system
decreased mast cell number ( J:32600 )
• numbers of connective tissue mast cells are greatly reduced relative to controls

immune system
decreased mast cell number ( J:32600 )
• numbers of connective tissue mast cells are greatly reduced relative to controls

integument
abnormal coat/hair pigmentation ( J:32600 )
• 18% of offspring show more severe pigment loss than either parental strain




Genotype
MGI:4431074
cx55
Allelic
Composition		 KitlSl-d/Kitl+
rs/rs
Genetic
Background		 involves: C3H/HeJ * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-d mutation (3 available); any Kitl mutation (92 available)
rs mutation (1 available); any rs mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
absent coat pigmentation ( J:125080 )
• completely white coat

integument
absent coat pigmentation ( J:125080 )
• completely white coat




Genotype
MGI:4431080
cx56
Allelic
Composition		 KitlSl-d/Kitl+
Ph/Ph+
Genetic
Background		 involves: C57BL/Gr * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-d mutation (3 available); any Kitl mutation (92 available)
Ph mutation (2 available); any Ph mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
abnormal coat/hair pigmentation ( J:125080 )
• the head and shoulder region have diluted pigment, and the rest of the body is white although some pigment patches do occur
head spot ( J:125080 )
• a small head spot is found occasionally

integument
abnormal coat/hair pigmentation ( J:125080 )
• the head and shoulder region have diluted pigment, and the rest of the body is white although some pigment patches do occur
head spot ( J:125080 )
• a small head spot is found occasionally




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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory