Kitl^Sl-Clo
Radiation induced Allele Detail

Summary

• Symbol: Kitl^Sl-Clo
• Name: kit ligand; steel cloud-gray
• MGI ID: MGI:1856162
• Synonyms: cg
• Gene: Kitl Location: Chr10:99851492-99936278 bp, + strand Genetic Position: Chr10, 51.4 cM
• Alliance: Kitl^Sl-Clo page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Radiation induced
• Mutation: Undefined
• Mutation details: This allele is defined by recovery of no wild-type mice from a mating of Kitl^Sl-cg/Kitl^Sl-type and +/+ mice.
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kitl Mutation: 92 strains or lines available

Notes

The cloud gray mutant was found in offspring of a neutron-irradiated male (J:13613). It was shown to be a steel allele by complementation test (J:13654). Homozygotes are very light gray with white blotches. Kitl^Sl-cg/+ mice are barely lighter than wild-type. They are fertile, but fertility of homozygotes is very poor (J:13613). About one-third of the homozygous females have imperforate vaginas. Kitl^Sl-cg/Kitl^Sl mice are off-white with dark ears and black eyes (J:13654).

References

• Original: J:13613 Owens J, Cloud-gray. Mouse News Lett. 1972;47:61
• All: 3 reference(s)