Kitl^Sl-m
Radiation induced Allele Detail

Summary

• Symbol: Kitl^Sl-m
• Name: kit ligand; mutant from steel
• MGI ID: MGI:1856166
• Gene: Kitl Location: Chr10:99851492-99936278 bp, + strand Genetic Position: Chr10, 51.4 cM
• Alliance: Kitl^Sl-m page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Radiation induced
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kitl Mutation: 92 strains or lines available

Notes

A C57BL/6 substrain exposed to low-level irradiation gave rise to this mutation (J:13416)(J:13137). Homozygotes are black-eyed white, anemic, and may survive up to one year. Males are sterile, but an occasional female may have one litter. Heterozygotes have diluted coat color and are otherwise normal. Gastrointestinal bleeding in homozygotes may cause them to lose about 3.5% of their blood volume daily (J:5009).

References

• Original: J:13416 Hollander WF, Two alleles of Sl. Mouse News Lett. 1964;30:29
• All: 3 reference(s)