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Fxyd3 Gene Detail
Summary
  • Symbol
    Fxyd3
  • Name
    FXYD domain-containing ion transport regulator 3
  • Synonyms
    Mat8
  • Feature Type
    protein coding gene
  • IDs
    MGI:107497
    NCBI Gene: 17178
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30769960-30776122 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 19.29 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    320 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107497
 protein coding gene Chr7:30767597-30776129 (-)
129S1/SvImJ ENSMUSG00200023055
 protein coding gene Chr7:20536608-20545167 (-)
A/J ENSMUSG00195040068
 protein coding gene Chr7:23212595-23221150 (-)
AKR/J ENSMUSG00220046250
 protein coding gene Chr7:21256628-21265173 (+)
BALB/cJ ENSMUSG00180014845
 protein coding gene Chr7:21272080-21280630 (-)
C3H/HeJ ENSMUSG00175035238
 protein coding gene Chr7:22356730-22365265 (-)
C57BL/6NJ ENSMUSG00215009341
 protein coding gene Chr7:20458928-20467460 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029560
 protein coding gene Chr7:30270135-30278806 (-)
CAST/EiJ ENSTCUG00005040070
 protein coding gene Chr7:22243634-22252279 (-)
CBA/J ENSMUSG00210025495
 protein coding gene Chr7:21519336-21527873 (-)
DBA/2J ENSMUSG00185051103
 protein coding gene Chr7:24593455-24601966 (-)
FVB/NJ ENSMUSG00205015696
 protein coding gene Chr7:21268816-21277350 (-)
JF1/MsJ ENSUMUG00000033035
 protein coding gene Chr7:29034892-29043397 (-)
LP/J ENSMUSG00230051631
 protein coding gene Chr7:29769898-29778446 (-)
NOD/ShiLtJ ENSMUSG00190007669
 protein coding gene Chr7:20936893-20945450 (-)
NZO/HlLtJ ENSMUSG00225023979
 protein coding gene Chr7:28600020-28608527 (-)
PWK/PhJ ENSLUMG00010018303
 protein coding gene Chr7:20962526-20971025 (-)
SPRET/EiJ ENSMSPG00010035989
 protein coding gene Chr7:20339550-20351544 (-)
WSB/EiJ ENSIUOG00005050139
 protein coding gene Chr7:15214385-15222893 (-)



Homology
more
  • Human Ortholog
    FXYD3, FXYD domain containing ion transport regulator 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FXYD3, FXYD domain containing ion transport regulator 3
  • Synonyms
    MAT8, PLML
  • Links
    NCBI Gene ID: 5349
    UniProt: Q14802

  • Chr Location
    19q13.12; chr19:35115521-35125653 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    689
  • Tissues
    17
  • cDNA Data
    67
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 17178 NCBI Gene Model | MGI Sequence Detail 6163 C57BL/6J ±  kb
transcript NM_008557 RefSeq | MGI Sequence Detail 524 C57BL/6  
polypeptide Q61835 UniProt | EBI | MGI Sequence Detail 88 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    cDNA 67

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36065
References
more
  • Summaries
    All 43
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:21836 Morrison BW, et al., neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors. Oncogene. 1994 Dec;9(12):3417-26
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory