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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cebpa
CCAAT/enhancer binding protein alpha
MGI:99480
57 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Cebpatm1.1(Cebpb)Ylee/Cebpatm1.1(Cebpb)Ylee
involves: 129X1/SvJ * C57BL/6 * FVB/N
abnormal brown adipose tissue morphology J:77646
abnormal fat cell morphology J:77646
abnormal hematopoietic system physiology J:77646
abnormal white adipose tissue morphology J:77646
decreased circulating leptin level J:77646
decreased white adipose tissue amount J:77646
normal growth/size/body region phenotype J:77646
normal homeostasis/metabolism phenotype J:77646
normal immune system phenotype J:77646
increased brown adipose tissue amount J:77646
increased food intake J:77646
normal reproductive system phenotype J:77646
Cebpatm1.1(Cebpb)Ylee/Cebpatm1.1Gonz
involves: 129X1/SvJ * C57BL/6 * FVB/N
abnormal white adipose tissue morphology J:77646
decreased white adipose tissue amount J:77646
Cebpatm1Gonz/Cebpa+
Cebpbtm1Nerl/Cebpbtm1Nerl
Tg(KRT14-cre)1Cgn/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2
normal integument phenotype J:154022
Cebpatm1Gonz/Cebpatm1Gonz
Cebpbtm1Es/Cebpbtm1Es
Tg(KRT14-cre/ERT)20Efu/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
abnormal epidermal layer morphology J:158721
abnormal epidermis stratum basale morphology J:158721
abnormal epidermis stratum spinosum morphology J:158721
abnormal epidermis suprabasal layer morphology J:158721
abnormal eye morphology J:158721
abnormal hair follicle infundibulum morphology J:158721
abnormal keratinocyte differentiation J:158721
abnormal male preputial gland morphology J:158721
abnormal Meibomian gland morphology J:158721
abnormal sebaceous gland morphology J:158721
abnormal sebaceous lipid secretion J:158721
abnormal sebocyte differentiation J:158721
abnormal sebocyte morphology J:158721
dry eyes J:158721
epidermal hyperplasia J:158721
hair follicle outer root sheath hyperplasia J:158721
hyperkeratosis J:158721
increased keratinocyte proliferation J:158721
Meibomian gland atrophy J:158721
parakeratosis J:158721
Cebpatm1Gonz/Cebpatm1Gonz
Cebpbtm1Nerl/Cebpbtm1Nerl
Tg(KRT14-cre)1Cgn/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2
abnormal epidermal layer morphology J:154022
eyelids open at birth J:154022
increased keratinocyte proliferation J:154022
neonatal lethality, complete penetrance J:154022
parakeratosis J:154022
shiny skin J:154022
tight skin J:154022
weight loss J:154022
Cebpatm1Gonz/Cebpatm1Gonz
Lepob/Lepob
Tg(Alb1-cre)1Dlr/0
involves: 129X1/SvJ * C57BL/6J * FVB/N
abnormal fat cell morphology J:93579
abnormal lipid homeostasis J:93579
decreased circulating cholesterol level J:93579
decreased circulating HDL cholesterol level J:93579
decreased circulating insulin level J:93579
decreased circulating LDL cholesterol level J:93579
decreased liver cholesterol level J:93579
decreased liver triglyceride level J:93579
decreased susceptibility to diet-induced hepatic steatosis J:93579
decreased susceptibility to diet-induced obesity J:93579
impaired glucose tolerance J:93579
increased circulating free fatty acids level J:93579
increased circulating glucose level J:93579
increased circulating VLDL cholesterol level J:93579
increased liver glycogen level J:93579
insulin resistance J:93579
Cebpatm1Gonz/Cebpatm2Nerl
Cebpbtm1Nerl/Cebpbtm1Nerl
Tg(KRT14-cre)1Cgn/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2
abnormal epidermis stratum corneum morphology J:154022
abnormal epidermis stratum granulosum morphology J:154022
increased keratinocyte proliferation J:154022
shiny skin J:154022
Cebpatm1Gonz/Cebpatm9Nerl
Cebpbtm1Nerl/Cebpbtm1Nerl
Tg(KRT14-cre)1Cgn/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2
absent epidermis stratum corneum J:154022
absent epidermis stratum granulosum J:154022
increased keratinocyte proliferation J:154022
parakeratosis J:154022
shiny skin J:154022

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory