79 phenotypes from 8 alleles in 14 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ighg1tm1(cre)Cgn/0 Mef2ctm2Eno/Mef2ctm2Eno involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6	decreased germinal center B cell number	J:265465
Mef2cm1Anu/Mef2c+ C57BL/6NCrlAnu-Mef2cm1Anu/Anu	no abnormal phenotype detected	J:104190
Mef2cm1Anu/Mef2cm1Anu C57BL/6NCrlAnu-Mef2cm1Anu/Anu	prenatal lethality	J:104190
Mef2ctm1.1Jjs/Mef2ctm1.1Jjs involves: 129S4/SvJaeSor * 129S6/SvEvTac	embryonic growth retardation	J:100949
	increased sinoatrial node size	J:100949
	ventricular hypoplasia	J:100949
Mef2ctm1Eno/Mef2c+ involves: 129S7/SvEvBrd	failure of sternum ossification	J:119152
	normal mortality/aging	J:122483
Mef2ctm1Eno/Mef2ctm1Eno involves: 129S7/SvEvBrd	abnormal blood vessel morphology	J:56426
	abnormal cardiovascular system morphology	J:40724
	abnormal definitive hematopoiesis	J:56426
	abnormal heart development	J:40724
	abnormal sinus venosus morphology	J:40724
	abnormal vitelline vasculature morphology	J:56426
	decreased cardiac muscle contractility	J:40724
	decreased ventricle muscle contractility	J:40724
	embryonic growth retardation	J:40724
	embryonic lethality during organogenesis, complete penetrance	J:40724
	failure of heart looping	J:40724
	incomplete somite formation	J:40724
	trabecula carnea hypoplasia	J:40724
	ventricular hypoplasia	J:40724
Mef2ctm1Eno/Mef2ctm1Eno involves: 129S7/SvEvBrd * C57BL/6	abnormal dorsal aorta morphology	J:50309
	abnormal endocardium morphology	J:50309
	abnormal pharyngeal arch artery morphology	J:50309
	abnormal vascular development	J:50309
	abnormal vascular endothelial cell development	J:50309
	abnormal vitelline vasculature morphology	J:50309
	dilated dorsal aorta	J:50309
	thin ventricular wall	J:50309
Mef2ctm1Eno/Mef2ctm1Jjs H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J * CBA/J	abnormal craniofacial development	J:122483
	abnormal dermal melanocyte morphology	J:173609
	abnormal epidermal melanocyte morphology	J:173609
	abnormal head morphology	J:122483
	abnormal mandibular angle morphology	J:122483
	abnormal melanocyte differentiation	J:173609
	abnormal melanosome morphology	J:173609
	abnormal pharyngeal arch morphology	J:122483
	abnormal respiratory system morphology	J:122483
	absent tympanic ring	J:122483
	cleft palate	J:122483
	cyanosis	J:122483
	decreased melanocyte number	J:173609
	decreased skin pigmentation	J:173609
	delayed bone ossification	J:122483
	glossoptosis	J:122483
	mandible hypoplasia	J:122483
	mandibular condyloid process hypoplasia	J:122483
	mandibular coronoid process hypoplasia	J:122483
	Meckel's cartilage hypoplasia	J:122483
	neonatal lethality, complete penetrance	J:122483
	normal nervous system phenotype	J:173609
	short mandible	J:122483
	temporal bone hypoplasia	J:122483
	zygomatic arch hypoplasia	J:122483
Mef2ctm1Eno/Mef2ctm1Jjs Myl2tm1(cre)Krc/Myl2+ involves: 129S4/SvJae * 129S6/SvEvTac * 129S7/SvEvBrd	no abnormal phenotype detected	J:100949
Mef2ctm1Eno/Mef2ctm1Jjs Tg(Myh6-cre)2182Mds/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N	no abnormal phenotype detected	J:100949
Mef2ctm1Eno/Mef2ctm2Eno Tg(Col2a1-cre)1Bhr/0 involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL	abnormal endochondral bone ossification	J:119152
	abnormal gait	J:119152
	decreased length of long bones	J:119152
	failure of sternum ossification	J:119152
	short limbs	J:119152
Mef2ctm1Eno/Mef2ctm2Eno Tg(Myog-cre)1Eno/0 involves: 129S/SvEv * 129S7/SvEvBrd	abnormal skeletal muscle fiber type ratio	J:127416
Mef2ctm1Eno/Mef2ctm2Eno Twist2tm1(cre)Dor/Twist2+ involves: 129S/SvEv * 129S7/SvEvBrd * 129X1/SvJ	abnormal endochondral bone ossification	J:119152
	abnormal trabecular bone morphology	J:119152
	failure of endochondral bone ossification	J:119152
	postnatal lethality, complete penetrance	J:119152
	respiratory distress	J:119152
	short fibula	J:119152
	short limbs	J:119152
	short tibia	J:119152
Mef2ctm1Jjs/Mef2ctm1Jjs Tg(Slc5a2-cre)1Tauc/0 involves: 129S6/SvEvTac * C57BL/6 * DBA/2	dilated distal convoluted tubule	J:158762
	dilated proximal convoluted tubule	J:158762
	dilated renal tubule	J:158762
	increased kidney cell proliferation	J:158762
	kidney cortex cyst	J:158762
Tg(Col2a1-Mef2c/VP16)1Eno/0 Not Specified	abnormal epiphyseal plate morphology	J:119152
	abnormal forelimb morphology	J:119152
	abnormal neurocranium morphology	J:119152
	premature endochondral bone ossification	J:119152
	short limbs	J:119152
Tg(Myh6-Mef2c)2Jmol/0 involves: FVB	abnormal heart atrium morphology	J:111573
	cardiac hypertrophy	J:111573
	decreased cardiac muscle contractility	J:111573
	dilated cardiomyopathy	J:111573
	dilated heart left ventricle	J:111573
	dilated heart ventricle	J:111573
	increased heart ventricle size	J:111573
Tg(Myh6-Mef2c/VP16)1Eno/0 Not Specified	abnormal skeletal muscle fiber type ratio	J:127416
	enhanced exercise endurance	J:127416