Tg(Col2a1-Mef2c/VP16)1Eno
Transgene Detail

Summary

• Symbol: Tg(Col2a1-Mef2c/VP16)1Eno
• Name: transgene insertion 1, Eric N Olson
• MGI ID: MGI:3719002
• Synonyms: Col2-MEF2C-VP16, MEF2C-VP16
• Transgene: Tg(Col2a1-Mef2c/VP16)1Eno Location: unknown
• Alliance: Tg(Col2a1-Mef2c/VP16)1Eno page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Col2a1-Mef2c/VP16)1Eno expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mef2c (MGI:99458)

• Mutation details: This transgene consists of the murine Col2a1 promoter and the chondrocyte-specific enhancer region and an in-frame fusion of the murine Mef2c and the viral coactivator VP16 activation domain. The promoter drives expression of Mef2c/VP16 in endochondral cartilage. (J:119152)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:119152 Arnold MA, et al., MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89
• All: 1 reference(s)