Sox11 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sox11
SRY (sex determining region Y)-box 11
MGI:98359

69 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Sox11^tm2.1Weg/Sox11^tm2.1Weg Sox4^tm1Vlf/Sox4^tm1Vlf H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129 * C57BL/6 * C57BL/6J * CBA/J	abnormal pharyngeal arch development	J:175338
Sox11^tm1.1Gan/Sox11^tm1.1Gan Sox4^tm1Vlf/Sox4^tm1Vlf Tg(Six3-cre)69Frty/0 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * DBA/2	abnormal eye development	J:199663
	abnormal retina bipolar cell morphology	J:199663
	abnormal retina outer plexiform layer morphology	J:199663
	absent optic nerve	J:199663
	absent retina ganglion cell	J:199663
	absent retina ganglion layer	J:199663
	absent retina inner plexiform layer	J:199663
	decreased amacrine cell number	J:199663
	decreased birth body size	J:199663
	decreased retina ganglion cell number	J:199663
	increased retina apoptosis	J:199663
	postnatal lethality, complete penetrance	J:199663
	thin retina ganglion layer	J:199663
Sox11^tm1Weg/Sox11^tm1Weg Sox4^tm1Vlf/Sox4^tm1Vlf Tg(Dbh-icre)1Gsc/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal nervous system development	J:157923
	abnormal sympathetic ganglion morphology	J:157923
Sox11^tm2.1Weg/Sox11^tm2.1Weg Sox4^tm1Vlf/Sox4^tm1Vlf Tg(Dbh-icre)1Gsc/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal innervation pattern to muscle	J:157923
	abnormal Meibomian gland morphology	J:157923
	abnormal stellate ganglion morphology	J:157923
	abnormal sympathetic neuron innervation pattern	J:157923
	blepharoptosis	J:157923
	small superior cervical ganglion	J:157923
Sox11^tm2.1Weg/Sox11^tm2.1Weg Sox4^tm1Vlf/Sox4^tm1Vlf Tg(Prrx1-cre)1Cjt/0 involves: 129 * C57BL/6 * SJL/J	abnormal limb mesenchyme morphology	J:175338
Sox11^tm2.1Weg/Sox11^tm2.1Weg Sox12^tm2.1Weg/Sox12^tm2.1Weg Sox4^tm1Vlf/Sox4^tm1Vlf involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	abnormal limb mesenchyme morphology	J:175338
Sox11^tm2.2Weg/Sox11⁺ Sox4^tm1.1Vlf/Sox4⁺ involves: 129 * C57BL/6 * FVB/N	abnormal bone mineralization	J:175338
	abnormal cranium morphology	J:175338
	abnormal lumbar vertebrae morphology	J:175338
	abnormal sternebra morphology	J:175338
	abnormal xiphoid process morphology	J:175338
	normal craniofacial phenotype	J:175338
	double outlet right ventricle	J:175338
	omphalocele	J:175338
	perinatal lethality, complete penetrance	J:175338
	small spleen	J:175338
	sternebra fusion	J:175338
	ventricular septal defect	J:175338
	normal vision/eye phenotype	J:175338
	wide cranial sutures	J:175338
Sox11^tm2.2Weg/Sox11⁺ Sox4^tm1.1Vlf/Sox4⁺ Tead2^tm1Hssk/Tead2^tm1Hssk involves: 129 * C57BL/6 * CBA * FVB/N	abnormal notochord morphology	J:175338
	abnormal vertebrae morphology	J:175338
	double outlet right ventricle	J:175338
	ventricular septal defect	J:175338
Sox11^tm2.2Weg/Sox11⁺ Sox4^tm1.1Vlf/Sox4^tm1.1Vlf involves: 129 * C57BL/6 * FVB/N	abnormal pharyngeal arch mesenchyme morphology	J:175338
	decreased embryo size	J:175338
	embryonic lethality during organogenesis, complete penetrance	J:175338
	failure of heart looping	J:175338
	incomplete embryo turning	J:175338
	open neural tube	J:175338
Sox11^tm2.2Weg/Sox11⁺ Sox12^tm2.1Weg/Sox12^tm2.1Weg Sox4^tm1.1Vlf/Sox4⁺ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	abnormal bone mineralization	J:175338
	abnormal cranium morphology	J:175338
	abnormal sternebra morphology	J:175338
	abnormal vertebrae morphology	J:175338
	double outlet right ventricle	J:175338
	persistent truncus arteriosus	J:175338
	small spleen	J:175338
	sternebra fusion	J:175338
	ventricular septal defect	J:175338
Sox11^tm2.2Weg/Sox11^tm2.2Weg Sox4^tm1.1Vlf/Sox4⁺ involves: 129 * C57BL/6 * FVB/N	abnormal eye development	J:175338
	abnormal lung development	J:175338
	abnormal skeleton development	J:175338
	aphakia	J:175338
	edema	J:175338
	eyelids open at birth	J:175338
	lethality throughout fetal growth and development, complete penetrance	J:175338
	micrognathia	J:175338
	microphthalmia	J:175338
	myocardium hypoplasia	J:175338
	persistent truncus arteriosus	J:175338
	semilunar valve hypoplasia	J:175338
	small lung	J:175338
	sternum hypoplasia	J:175338
Sox11^tm2.2Weg/Sox11^tm2.2Weg Sox4^tm1.1Vlf/Sox4^tm1.1Vlf involves: 129 * C57BL/6 * FVB/N	abnormal cell death	J:175338
	abnormal heart development	J:175338
	abnormal neural tube morphology	J:175338
	abnormal pharyngeal arch development	J:175338
	abnormal pharyngeal arch mesenchyme morphology	J:175338
	absent limb buds	J:175338
	cardia bifida	J:175338
	decreased cell proliferation	J:175338
	decreased embryo size	J:175338
	embryonic growth arrest	J:175338
	embryonic lethality during organogenesis, complete penetrance	J:175338
	impaired somite development	J:175338
	incomplete embryo turning	J:175338
	incomplete rostral neuropore closure	J:175338
	wavy neural tube	J:175338
Sox11^tm2.2Weg/Sox11^tm2.2Weg Sox4^tm1Vlf/Sox4^tm1Vlf Tg(Pou3f4-cre)32Cren/0 involves: 129 * C57BL/6 * CD-1 * FVB/N	abnormal neural tube morphology	J:175338
Sox11^tm2.2Weg/Sox11^tm2.2Weg Sox12^tm2.1Weg/Sox12^tm2.1Weg Sox4^tm1.1Vlf/Sox4^tm1.1Vlf involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	abnormal neural tube morphology	J:175338
	kinked neural tube	J:175338

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