About   Help   FAQ
Tg(Dbh-icre)1Gsc
Transgene Detail
Summary
Symbol: Tg(Dbh-icre)1Gsc
Name: transgene insertion 1, Gunther Schutz
MGI ID: MGI:4355551
Synonyms: DBHCre, DBHiCre
Transgene: Tg(Dbh-icre)1Gsc  Location: unknown  
Alliance: Tg(Dbh-icre)1Gsc page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Dbh-icre)1Gsc expression driven by 1 gene
 
Mutation detailsUsing ET recombination, the coding sequence of iCre, followed by the bovine growth hormone polyadenylation signal, was introduced in-frame with the ATG of the Dbh gene in a PAC. The 150 kb transgenic construct was injected into he male pronuclei of fertilized C57BL/6 oocytes. (J:128636)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Dbh (species not specified)
Summary of all recombinase alleles driven by Dbh.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:128636 Stanke M, et al., Target-dependent specification of the neurotransmitter phenotype: cholinergic differentiation of sympathetic neurons is mediated in vivo by gp 130 signaling. Development. 2006 Jan;133(1):141-50
All:  47 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory