49 phenotypes from 4 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Serpine1em1(IMPC)Tcp/Serpine1em1(IMPC)Tcp C57BL/6N-Serpine1em1(IMPC)Tcp/Tcp	abnormal sternum morphology	J:211773
	enlarged lymph nodes	J:211773
Serpine1tm1.1Vlp/Serpine1tm1.1Vlp involves: 129 * C57BL/6	decreased susceptibility to endotoxin shock	J:229191
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:229191
Serpine1tm1Mlg/Serpine1tm1Mlg B6.129S2-Serpine1tm1Mlg/J	abnormal enzyme/coenzyme activity	J:123733
	cardiac fibrosis	J:101486
	heart inflammation	J:101486
	increased angiogenesis	J:108675
	increased susceptibility to bacterial infection	J:124327
	increased susceptibility to Coronaviridae infection	J:288556
	increased susceptibility to Coronaviridae infection induced morbidity/mortality	J:288556
	increased susceptibility to induced morbidity/mortality	J:124327
	liver fibrosis	J:123733
	normal liver/biliary system phenotype	J:123733
	lung hemorrhage	J:288556
Serpine1tm1Mlg/Serpine1tm1Mlg involves: 129S2/SvPas	decreased susceptibility to endotoxin shock	J:229191
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:229191
Serpine1tm1Mlg/Serpine1tm1Mlg involves: 129S2/SvPas * C57BL/6	abnormal acute inflammation	J:133227
	abnormal blood circulation	J:67531
	abnormal body weight	J:87982
	abnormal energy expenditure	J:87982
	abnormal enzyme/coenzyme activity	J:133227
	abnormal epididymal fat pad morphology	J:87982
	abnormal interleukin level	J:133227
	abnormal lung morphology	J:31542
	decreased angiogenesis	J:65383
	decreased body weight	J:133227
	decreased circulating interleukin-6 level	J:133227
	decreased liver triglyceride level	J:87982
	decreased skeletal muscle triglyceride level	J:87982
	decreased subcutaneous adipose tissue amount	J:87982
	enhanced wound healing	J:72394
	glomerular crescent	J:85989
	glomerulonephritis	J:85989
	normal hematopoietic system phenotype	J:39819
	normal immune system phenotype	J:133227
	increased acute inflammation	J:133227
	increased body temperature	J:87982
	increased granulocyte number	J:133227
	increased oxygen consumption	J:87982
	increased urine protein level	J:85989
	normal neoplasm	J:33232
	respiratory system inflammation	J:66093
	weight loss	J:133227
Serpine1tm1Mlg/Serpine1tm1Mlg involves: 129S2/SvPas * C57BL/6 * C57BLKS/J	abnormal kidney morphology	J:127478
	abnormal renal glomerulus morphology	J:127478
	decreased circulating cholesterol level	J:127478
	normal homeostasis/metabolism phenotype	J:127478
	hyperglycemia	J:127478
	increased blood urea nitrogen level	J:127478
Tg(CMV-Serpine1)1Dgi/0 B6.Cg-Tg(CMV-Serpine1)1Dgi	normal cardiovascular system phenotype	J:61287
Tg(CMV-Serpine1)1Dgi/0 involves: C57BL/6J * SJL/J	abnormal lung morphology	J:31542
	normal neoplasm	J:33232
	pulmonary fibrosis	J:31542, J:140007