About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Jun
jun proto-oncogene
MGI:96646
96 phenotypes from 10 alleles in 18 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Isl1tm1(cre)Sev/Isl1+
Juntm4Wag/Jun+
Not Specified
interrupted aortic arch, type b J:199412
Junem1(IMPC)Mbp/Jun+
C57BL/6N-Junem1(IMPC)Mbp/MbpMmucd
abnormal blood vessel morphology J:211773
abnormal craniofacial morphology J:211773
abnormal eye morphology J:211773
abnormal lymph node morphology J:211773
abnormal placenta morphology J:211773
anophthalmia J:211773
edema J:211773
enlarged lymph nodes J:211773
hyperactivity J:211773
increased prepulse inhibition J:211773
Junem1(IMPC)Mbp/Junem1(IMPC)Mbp
C57BL/6N-Junem1(IMPC)Mbp/MbpMmucd
abnormal blood vessel morphology J:211773
abnormal neural tube morphology J:211773
abnormal placenta morphology J:211773
edema J:211773
embryonic growth retardation J:211773
hemorrhage J:211773
preweaning lethality, complete penetrance J:211773
Juntm1Bdc/Juntm1Bdc
Not Specified
decreased neuron apoptosis J:78265
Juntm1Pa/Juntm1Pa
either: (involves: 129S/SvEv * 129X1/SvJ) or (involves: 129X1/SvJ * C57BL/6J)
decreased fibroblast proliferation J:13175
embryonic lethality during organogenesis, complete penetrance J:13175
Juntm1Pa/Juntm4Wag
Isl1tm1(cre)Sev/Isl1+
involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ * C57BL/6J
normal cardiovascular system phenotype J:199412
normal embryo phenotype J:199412
Juntm1Pa/Juntm4Wag
Tg(Tek-cre)1Ywa/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL
normal embryo phenotype J:199412
Juntm1Rsjo/Juntm1Rsjo
Tg(KRT14-cre)8Brn/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N
abnormal eyelid development J:84743
abnormal keratinocyte morphology J:84743
abnormal keratinocyte physiology J:84743
decreased keratinocyte proliferation J:84743
delayed wound healing J:84743
eye opacity J:84743
eyelids open at birth J:84743
failure of eyelid fusion J:84743
impaired wound healing J:84743
increased incidence of corneal inflammation J:84743
microphthalmia J:84743
Juntm1Wag/Juntm1Wag
either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
abnormal bile duct development J:14538
abnormal forebrain morphology J:14538
abnormal liver development J:14538
blood vessel congestion J:14538
dissociated hepatocytes J:14538
edema J:14538
embryonic lethality during organogenesis, incomplete penetrance J:14538
hepatic necrosis J:14538
increased hepatocyte apoptosis J:14538
increased nucleated erythrocyte cell number J:14538
lethality throughout fetal growth and development, complete penetrance J:14538
Juntm1Wag/Juntm1Wag
involves: 129S2/SvPas
decreased cell proliferation J:175212
oxidative stress J:175212
Juntm1Wag/Juntm1Wag
involves: 129S2/SvPas * C57BL/6
abnormal cardiac neural crest cell migration J:55508
decreased heart right ventricle wall thickness J:55508
decreased hepatocyte proliferation J:55508
increased hepatocyte apoptosis J:55508
persistent truncus arteriosus J:55508
right aortic arch J:55508
ventricular septal defect J:55508
Juntm1Wag/Juntm5.1(Junb)Wag
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
lethality throughout fetal growth and development, complete penetrance J:75359
Juntm2.1Wag/Juntm2.1Wag
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
decreased body size J:53481
decreased body weight J:53481
decreased cell proliferation J:53481
decreased cellular sensitivity to ultraviolet irradiation J:53481
decreased susceptibility to neuronal excitotoxicity J:53481
decreased susceptibility to pharmacologically induced seizures J:53481
Juntm3.1Wag/Juntm3.1Wag
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
no abnormal phenotype detected J:53481
Juntm4Wag/Juntm4Wag
Isl1tm1(cre)Sev/Isl1+
involves: 129P2/OlaHsd * 129S/Sv
abnormal aortic valve morphology J:199412
abnormal cardiac outflow tract development J:199412
abnormal pharyngeal arch artery morphology J:199412
abnormal pulmonary valve cusp morphology J:199412
abnormal pulmonary valve morphology J:199412
double outlet right ventricle J:199412
interrupted aortic arch, type b J:199412
normal mortality/aging J:199412
retroesophageal right subclavian artery J:199412
semilunar valve hyperplasia J:199412
ventricular septal defect J:199412
Juntm4Wag/Juntm4Wag
Tg(Alb1-cre)7Gsc/0
involves: 129P2/OlaHsd * FVB/N
abnormal liver regeneration J:75863
decreased body size J:75863
decreased liver weight J:75863
Juntm4Wag/Juntm4Wag
Tg(COL2A1-cre)1Wag/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
abnormal thoracic cage morphology J:80022
scoliosis J:80022
Juntm4Wag/Juntm4Wag
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
abnormal liver regeneration J:75863
Juntm4Wag/Juntm4Wag
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
decreased neuron apoptosis J:176956
normal nervous system phenotype J:176956
Juntm4Wag/Juntm4Wag
Tg(Nes-cre)1Wme/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
decreased body length J:80022
decreased body size J:80022
eyelids open at birth J:80022
fusion of vertebral arches J:80022
kyphosis J:80022
postnatal lethality, incomplete penetrance J:80022
prenatal lethality, incomplete penetrance J:80022
scoliosis J:80022
Juntm4Wag/Juntm4Wag
Tg(Sftpc-cre)1Blh/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
abnormal cytokine level J:179883
abnormal pulmonary alveolar parenchyma morphology J:179883
abnormal pulmonary alveolar system morphology J:179883
abnormal tumor necrosis factor level J:179883
emphysema J:179883
increased lung apoptosis J:179883
lung inflammation J:179883
Juntm4Wag/Juntm4Wag
Tg(Tek-cre)1Ywa/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
normal cardiovascular system phenotype J:199412
double outlet right ventricle J:199412
mitral valve hyperplasia J:199412
normal mortality/aging J:199412
perimembraneous ventricular septal defect J:199412
pulmonary valve hyperplasia J:199412
thick mitral valve cusps J:199412
thick pulmonary valve cusps J:199412
thin right ventricle myocardium compact layer J:199412
Juntm5.1(Junb)Wag/Juntm5.1(Junb)Wag
involves: 129P2/OlaHsd * C57BL/6
abnormal cell proliferation J:75359
abnormal truncus arteriosus septation J:75359
cyanosis J:75359
eyelids open at birth J:75359
failure of eyelid fusion J:75359
normal liver/biliary system phenotype J:75359
neonatal lethality, incomplete penetrance J:75359
perinatal lethality, incomplete penetrance J:75359
persistent truncus arteriosus J:75359
postnatal lethality, complete penetrance J:75359
ventricular septal defect J:75359
Juntm6.1(Jund)Wag/Juntm6.1(Jund)Wag
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal neural tube morphology J:175212
decreased cell proliferation J:175212
embryonic growth retardation J:175212
embryonic lethality during organogenesis, incomplete penetrance J:175212
exencephaly J:175212
eyelids open at birth J:175212
normal liver/biliary system phenotype J:175212
neonatal lethality, complete penetrance J:175212
oxidative stress J:175212
persistent truncus arteriosus J:175212

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory