108 phenotypes from 30 alleles in 31 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Grid2ho-2Btlr/Grid2ho-2Btlr C57BL/6J-Grid2ho-2Btlr	abnormal gait	J:225267
Grid2ho-4J/Grid2ho-4J DBA/2J-Grid2ho-4J/J	abnormal cerebellar cortex morphology	J:82371
	abnormal cerebellar granule layer morphology	J:82371
	abnormal CNS synapse formation	J:82371
	abnormal locomotor coordination	J:82371
	abnormal motor learning	J:82371, J:137190
	abnormal neuron mitochondrial morphology	J:137190
	abnormal Purkinje cell dendrite morphology	J:82371
	abnormal Purkinje cell innervation	J:82371
	ataxia	J:82371
	impaired balance	J:82371
	impaired coordination	J:82371
	reduced linear vestibular evoked potential	J:116914
Grid2ho-4J/Grid2ho-Tg37Inra involves: C57BL/6 * CBA * DBA/2J	jerky movement	J:44452
Grid2ho-5J/Grid2ho-5J involves: C57BLKS/J	male infertility	J:13443
	stereotypic behavior	J:13443
Grid2ho-8J/Grid2ho-8J B10.D2/nSnJ	abnormal gait	J:155927
	abnormal locomotor activation	J:155927
	abnormal locomotor coordination	J:155927
	impaired balance	J:155927
	muscle spasm	J:155927
	reduced female fertility	J:155927
	reduced male fertility	J:155927
Grid2ho-11J/Grid2ho-11J involves: C57BLKS/J	abnormal gait	J:155858
Grid2ho-13J/Grid2ho-13J B10.D2/nSnJ	abnormal gait	J:50994
Grid2ho-15J/Grid2ho-15J C3(Cg)-Grid2ho-15J/GrsrJ	abnormal gait	J:94301
	abnormal head movements	J:94301
	abnormal sexual interaction	J:94301
	ataxia	J:94301
Grid2ho-15J/Grid2ho-15J involves: C3HeB/Fe	abnormal eye movement	J:220519
	ataxia	J:220519
Grid2ho-16J/Grid2ho-16J C57BL/6J-Grid2ho-16J/J	abnormal gait	J:87349
	muscle spasm	J:87349
	tremors	J:87349
Grid2ho-17J/Grid2ho-17J C57BL/6J-Grid2ho-17J/J	abnormal gait	J:87349
	ataxia	J:87349
	tremors	J:87349
Grid2ho-18J/Grid2ho-18J B6.Cg-Grid2ho-18J/GrsrJ	ataxia	J:212310
	increased or absent threshold for auditory brainstem response	J:212310
	male infertility	J:212310
Grid2ho-19J/Grid2ho-19J C57BL/6J-Grid2ho-19J/GrsrJ	ataxia	J:212311
	decreased body size	J:212311
Grid2ho-20J/Grid2ho-20J B6(Cg)-Grid2ho-20J/GrsrJ	abnormal gait	J:212897
	normal reproductive system phenotype	J:212897
	tremors	J:212897
Grid2ho-21J/Grid2ho-21J C57BL/6J-Grid2ho-21J/GrsrJ	abnormal gait	J:212897
	normal reproductive system phenotype	J:212897
	normal vision/eye phenotype	J:212897
Grid2ho-Btlr/Grid2ho-Btlr C57BL/6J-Grid2ho-Btlr	abnormal gait	J:148981
	impaired balance	J:148981
	lethargy	J:148981
	male infertility	J:148981
	weaving	J:148981
Grid2ho-cpr/Grid2ho-cpr involves: C57BL/10J * DBA/2J	abnormal motor capabilities/coordination/movement	J:13994
	abnormal myelination	J:13994
	abnormal resting posture	J:13994
	ataxia	J:13994
	athetotic walking movements	J:13994
	decreased survivor rate	J:13994
	male infertility	J:13994
	postnatal lethality	J:13994
Grid2ho-Jic/Grid2ho-Jic either: B10.Cg-Grid2ho-Jic H2u or (involves: C57BL/10SnSg * DBA/2 * PL/J)	abnormal gait	J:14256
Grid2ho-Jwg/Grid2ho-Jwg Not Specified	abnormal gait	J:10295, J:14140
	abnormal sperm flagellum morphology	J:10295
	abnormal sperm motility	J:10295
	ataxia	J:10295, J:14140
	impaired fertilization	J:10295
	impaired sperm penetration of zona pellucida	J:10295
	normal nervous system phenotype	J:10295
	reduced female fertility	J:10295
	reduced male fertility	J:10295, J:14140
Grid2ho-Nancy/Grid2ho-Nancy involves: C57BL/6	abnormal cerebellar granule layer morphology	J:82371, J:82709
	abnormal cerebellar molecular layer	J:82709
	abnormal CNS synapse formation	J:82371, J:82709
	abnormal gait	J:82709
	abnormal locomotor coordination	J:82371
	abnormal posture	J:82709
	abnormal Purkinje cell dendrite morphology	J:82371, J:82709
	abnormal Purkinje cell innervation	J:82371
	abnormal Purkinje cell morphology	J:82371, J:82709
	abnormal sensory capabilities/reflexes/nociception	J:82709
	ataxia	J:82371
	cerebellum atrophy	J:82709
	impaired balance	J:82371, J:82709
	impaired coordination	J:82371
	limb grasping	J:82709
	retropulsion	J:82709
	short stride length	J:82709
	small cerebellum	J:82709
Grid2ho/Grid2ho involves: C57BLKS/J	abnormal gait	J:13443
	abnormal locomotor activation	J:13443
	abnormal locomotor coordination	J:13443
	abnormal motor coordination/balance	J:18056
	abnormal synaptic neurotransmitter level	J:18056
	male infertility	J:13443
	stereotypic behavior	J:13443
Grid2Lc-J/Grid2+ BALB/cByJ-Grid2Lc-J/+	abnormal cerebellar foliation	J:42385
	abnormal gait	J:42385
	abnormal posture	J:42385
	ataxia	J:42385
	Purkinje cell degeneration	J:42385
	titubation	J:42385
	weaving	J:42385
Grid2Lc-J/Grid2+ involves: 129X1/SvJ * BALB/cByJ * C57BL/6	abnormal cerebellar granule layer morphology	J:62117
	abnormal cerebellar Purkinje cell layer	J:62117
	abnormal Purkinje cell dendrite morphology	J:62117
	ataxia	J:62117
	cerebellum atrophy	J:62117
	decreased Purkinje cell number	J:62117
	reduced cerebellar foliation	J:62117
Grid2Lc-J/Grid2Lc-J BALB/cByJ-Grid2Lc-J/+	hypoxia	J:42385
	lethality at weaning, complete penetrance	J:42385
	neonatal lethality, incomplete penetrance	J:42385
Grid2Lc/Grid2+ B6CBACa Aw-J/A-Grid2Lc/J	abnormal grooming behavior	J:50315
	ataxia	J:39109
	Purkinje cell degeneration	J:39109
	reduced linear vestibular evoked potential	J:116914
Grid2Lc/Grid2+ involves: C57BL/6 * CBA	decreased exploration in new environment	J:107881
	hyperactivity	J:107881
	increased circulating adrenocorticotropin level	J:44206
	increased circulating corticosterone level	J:44206
Grid2Lc/Grid2+ involves: C57BL/6 * CBA/CaGnLe	abnormal optokinetic reflex	J:101081
	abnormal vestibuloocular reflex	J:101081
Grid2Lc/Grid2+ involves: STOCK MitfMi-wh	abnormal cochlear VIII nucleus morphology	J:121314
	abnormal discrimination learning	J:13161
	abnormal motor coordination/balance	J:158918
	abnormal spatial learning	J:30686
	ataxia	J:158918
	decreased Purkinje cell number	J:121314
	impaired coordination	J:158918
Grid2Lc/Grid2ho-Nancy involves: C57BL/6 * STOCK MitfMi-wh	abnormal autophagy	J:82240
	abnormal cerebellar granule layer morphology	J:82240
	abnormal cerebellum development	J:82240
	abnormal Purkinje cell morphology	J:82240
	ataxia	J:82240
	cerebellum atrophy	J:82240
	Purkinje cell degeneration	J:82240
	reduced cerebellar foliation	J:82240
	thin external granule cell layer	J:82240
Grid2Lc/Grid2Lc B6CBACa Aw-J/A-Grid2Lc/J	abnormal cerebellum development	J:39109
	abnormal hindbrain morphology	J:39109
	abnormal midbrain morphology	J:39109
	abnormal suckling behavior	J:39109
	abnormal trigeminal motor nucleus morphology	J:39109
	absent gastric milk in neonates	J:39109
	decreased birth weight	J:39109
	neonatal lethality, complete penetrance	J:39109
Grid2tm1(cre)Mwa/Grid2tm1(cre)Mwa involves: C57BL/6N	abnormal eye movement	J:220519
	normal nervous system phenotype	J:170673
Grid2tm1(cre/PGR*)Ksak/Grid2tm1(cre/PGR*)Ksak C57BL/6-Grid2tm1(cre/PGR*)Ksak	ataxia	J:150621
	impaired coordination	J:150621
Grid2tm1(cre/PGR*)Ksak/Grid2tm2Mim involves: C57BL/6	abnormal Purkinje cell morphology	J:97405
Grid2tm1Mim/Grid2tm1Mim B6.Cg-Grid2tm1Mim	abnormal action potential	J:97010
	abnormal eye blink conditioning behavior	J:89436, J:107990
	abnormal eye movement	J:97010, J:101081
	abnormal optokinetic reflex	J:101081
	abnormal reflex	J:101081
	abnormal vestibuloocular reflex	J:101081
	impaired coordination	J:97010
	increased prepulse inhibition	J:89405
Grid2tm1Mim/Grid2tm1Mim involves: C57BL/6 * CBA	abnormal cerebellar molecular layer	J:73385
	abnormal cerebellum morphology	J:73385
	abnormal CNS synapse formation	J:24975
	abnormal CNS synaptic transmission	J:24975, J:109764
	abnormal excitatory postsynaptic currents	J:73385
	abnormal GABA-mediated receptor currents	J:109764
	abnormal gait	J:24975
	abnormal locomotor activation	J:24975
	abnormal motor coordination/balance	J:24975
	abnormal Purkinje cell innervation	J:24975, J:73385
	abnormal Purkinje cell morphology	J:24975
	abnormal response to injury	J:36182
	absent long-term depression	J:24477
	ataxia	J:24975
	decreased locomotor activity	J:24975
	decreased vertical activity	J:24975
	head tilt	J:36182
	impaired coordination	J:24975
	impaired righting response	J:36182
	increased miniature inhibitory postsynaptic current amplitude	J:109764
	thin cerebellar molecular layer	J:73385
Grid2tm1Mmsh/Grid2tm1Mmsh involves: C57BL/6N	abnormal CNS synaptic transmission	J:127449
	abnormal excitatory postsynaptic currents	J:127449
	abnormal Purkinje cell morphology	J:127449
	normal behavior/neurological phenotype	J:127449
	normal nervous system phenotype	J:127449
	prolonged excitatory postsynaptic current decay time	J:127449
	prolonged excitatory postsynaptic current rise time	J:127449
	reduced long-term depression	J:127449
Grid2tm2Msmh/Grid2tm2Msmh C57BL/6-Grid2tm2Msmh	abnormal Purkinje cell dendrite morphology	J:150621
	abnormal synapse morphology	J:150621
	normal behavior/neurological phenotype	J:150621
Grid2tpr/Grid2tpr involves: B10.D2/nSnJ	abnormal gait	J:84411
	ataxia	J:84411
Grid2ts3/Grid2ts3 C57BL/6J-Grid2ts3	abnormal cerebellar molecular layer	J:222504
	abnormal cerebellum lobule morphology	J:222504
	abnormal CNS synapse formation	J:222504
	abnormal fertility/fecundity	J:222504
	abnormal gait	J:222504
	abnormal motor coordination/balance	J:222504
	abnormal Purkinje cell dendrite morphology	J:222504
	abnormal Purkinje cell morphology	J:222504
	ataxia	J:222504
	cerebellum atrophy	J:222504
	decreased body size	J:222504
	decreased body weight	J:222504
	decreased cerebellar granule cell number	J:222504
	decreased Purkinje cell number	J:222504
	hindlimb paralysis	J:222504
	impaired limb coordination	J:222504
	impaired righting response	J:222504
	limb grasping	J:222504
	short stride length	J:222504
	small cerebellum	J:222504