Adipor1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adipor1
adiponectin receptor 1
MGI:1919924

48 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adipor1^tm1.1Kry/Adipor1^tm1.1Kry Tg(Col1a1-cre)1Kry/0 involves: 129 * C57BL/6J * FVB	normal homeostasis/metabolism phenotype	J:199264
	normal skeleton phenotype	J:199264
Adipor1^{tm1b(EUCOMM)Hmgu}/Adipor1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Adipor1^{tm1b(EUCOMM)Hmgu}/H	abnormal heart left ventricle morphology	J:211773
	abnormal retina morphology	J:211773
	decreased circulating calcium level	J:211773
	decreased hemoglobin content	J:211773
	decreased lymphocyte cell number	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating phosphate level	J:211773
	increased neutrophil cell number	J:211773
	increased red blood cell distribution width	J:211773
Adipor1^{tm1b(EUCOMM)Hmgu}/Adipor1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Adipor1^{tm1b(EUCOMM)Hmgu}/Orl	abnormal auditory brainstem response	J:211773
	abnormal retina morphology	J:211773
	abnormal retina outer nuclear layer morphology	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased circulating calcium level	J:211773
	decreased cornea thickness	J:211773
	decreased exploration in new environment	J:211773
	decreased total retina thickness	J:211773
	increased circulating phosphate level	J:211773
	increased circulating triglyceride level	J:211773
Adipor1^tm1Dgen/Adipor1^tm1Dgen B6.129P2-Adipor1^tm1Dgen/Mmnc	abnormal lipid homeostasis	J:122027
	decreased energy expenditure	J:122027
	decreased locomotor activity	J:122027
	impaired glucose tolerance	J:122027
	increased brown adipose tissue amount	J:122027
	increased circulating cholesterol level	J:122027
	increased circulating leptin level	J:122027
	increased liver triglyceride level	J:122027
	increased percent body fat/body weight	J:122027
	increased susceptibility to weight gain	J:122027
	increased white adipose tissue amount	J:122027
Adipor1^tm1Dgen/Adipor1^tm1Dgen involves: 129P2/OlaHsd	abnormal adaptive thermogenesis	J:210480
	decreased adiponectin level	J:210480
	decreased circulating adiponectin level	J:210480
	impaired adaptive thermogenesis	J:210480
Adipor1^tm1Dgen/Adipor1^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:101679
Adipor1^tm1Tka/Adipor1^tm1Tka involves: 129S4/SvJae * C57BL/6	abnormal enzyme/coenzyme activity	J:117919
	abnormal glucose homeostasis	J:117919
	hyperglycemia	J:117919
	impaired glucose tolerance	J:117919
	increased circulating glucose level	J:117919
	increased circulating insulin level	J:117919
	insulin resistance	J:117919
Adipor1^tm2Tka/Adipor1^tm2Tka Tg(Ckmm-cre)5Khn/0 B6.Cg-Adipor1^tm2Tka Tg(Ckmm-cre)5Khn	abnormal glucose homeostasis	J:159462
	abnormal skeletal muscle fiber mitochondrial morphology	J:159462
	abnormal skeletal muscle fiber type ratio	J:159462
	decreased oxygen consumption	J:159462
	impaired exercise endurance	J:159462
	increased circulating glucose level	J:159462
	increased circulating insulin level	J:159462
	increased skeletal muscle triglyceride level	J:159462
	insulin resistance	J:159462
	oxidative stress	J:159462

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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