Abcb10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abcb10
ATP-binding cassette, sub-family B member 10
MGI:1860508

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Abcb10^tm1.1Tafu/Abcb10^tm1.2Tafu Tg(Mx1-cre)1Cgn/0 involves: C57BL/6J * C57BL/6NCrlj * CBA/J * CBA/JNCrlJ	abnormal erythropoiesis	J:223428
	abnormal hemoglobin	J:223428
	abnormal iron level	J:223428
	abnormal mitochondrial morphology	J:223428
	decreased erythrocyte cell number	J:223428
	decreased hemoglobin content	J:223428
	decreased mean corpuscular hemoglobin concentration	J:223428
	decreased mean corpuscular volume	J:223428
	hypochromic microcytic anemia	J:223428
	reticulocytosis	J:223428
Abcb10^tm1.2Tafu/Abcb10^tm1.2Tafu involves: C57BL/6NCrlj * CBA/JNCrlj	abnormal blood cell morphology	J:223428
	abnormal embryonic hematopoiesis	J:223428
	abnormal hemoglobin	J:223428
	abnormal hepatocyte morphology	J:223428
	abnormal iron level	J:223428
	abnormal liver morphology	J:223428
	abnormal liver physiology	J:223428
	embryonic lethality during organogenesis, complete penetrance	J:223428
	oxidative stress	J:223428
	pallor	J:223428
Abcb10^tm1Lex/Abcb10⁺ involves: 129S/SvEvBrd * C57BL/6	abnormal mitochondrial physiology	J:189396
	normal cardiovascular system phenotype	J:189396
	decreased systemic arterial systolic blood pressure	J:189396
	increased response of heart to induced stress	J:189396
	increased systemic arterial diastolic blood pressure	J:189396
	oxidative stress	J:189396
Abcb10^tm1Lex/Abcb10^tm1Lex involves: 129S/SvEvBrd * C57BL/6	embryonic lethality, complete penetrance	J:189396

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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