About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
MGI:107940
15 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Braftm1Mmcm/Braf+
Ezh2tm1.1Nesh/Ezh2+
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB 		increased melanoma incidence J:239472
Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Ezh2tm1.1Nesh/Ezh2+
Nrastm1.1Nesh/Nras+
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129 * 129S4/SvJae * 129P2/OlaHsd * C57BL/6 * FVB 		increased melanoma incidence J:239472
Ezh1tm1Jnw/Ezh1tm1Jnw
Ezh2tm1Tara/Ezh2tm1Tara
Tg(KRT14-cre)1Efu/0
involves: 129P2/OlaHsd 		abnormal hair follicle infundibulum morphology J:169295
abnormal hair follicle outer root sheath morphology J:169295
abnormal hair growth J:169295
absent gastric milk in neonates J:169295
epidermal hyperplasia J:169295
hair follicle degeneration J:169295
increased hair follicle apoptosis J:169295
normal integument phenotype J:169295
neonatal lethality, complete penetrance J:169295
small hair follicles J:169295
Ezh2tm1.1Nesh/Ezh2+
Nrastm1.1Nesh/Nras+
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB 		normal neoplasm J:239472
Ezh2tm1Tara/Ezh2tm1Tara
Ightm2Cgn/?
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * CBA 		normal immune system phenotype J:83216
Ezh2tm2Sho/Ezh2+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Kdm6btm1.1Rbo/Kdm6btm1.1Rbo
involves: 129S1/Sv * 129S4/SvJae * C57BL/6J * CBA/J 		cleft palate J:323190
normal craniofacial phenotype J:323190
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory