About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cdh5
cadherin 5
MGI:105057
71 phenotypes from 12 alleles in 10 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Cdh5tm1.1Ics/Cdh5tm1.1Ics
B6.129(Cg)-Cdh5tm1.1Ics
abnormal ovary morphology J:214298
abnormal uterus morphology J:214298
abnormal vascular endothelial cell morphology J:214298
edema J:214298
enlarged endometrial glands J:214298
enlarged ovary J:214298
enlarged uterus J:214298
increased vascular permeability J:214298
ovarian follicular cyst J:214298
ovary cyst J:214298
ovary fibrosis J:214298
uterus fibrosis J:214298
uterus hypertrophy J:214298
Cdh5tm1.1Pec/Cdh5tm1.1Pec
Not Specified
abnormal angiogenesis J:56509
abnormal cardiac outflow tract development J:56509
abnormal intersomitic vessel morphology J:56509
abnormal placenta vasculature J:56509
abnormal somite development J:56509
abnormal vascular development J:56509
abnormal vascular endothelial cell development J:56509
abnormal vasculogenesis J:56509
abnormal vein development J:56509
abnormal vitelline vasculature morphology J:56509
delayed heart development J:56509
embryonic growth arrest J:56509
embryonic lethality during organogenesis, complete penetrance J:56509
normal hematopoietic system phenotype J:56509
increased apoptosis J:56509
small pharyngeal arch J:56509
Cdh5tm1Dvst/Cdh5tm1Dvst
Tg(Cdh5-cre/ERT2)1Rha/0
Not Specified
abnormal retina vasculature morphology J:189010
Cdh5tm1Dvst/Cdh5tm1Dvst
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0
involves: C57BL/6 * CBA
abnormal retina development J:328283
decreased angiogenesis J:328283
hemorrhage J:328283
increased angiogenesis J:328283
Cdh5tm1Hub/Cdh5tm1Hub
involves: 129S1/Sv * 129X1/SvJ
abnormal vasculogenesis J:98466
Cdh5tm1Hub/Cdh5tm1Hub
involves: 129S1/Sv * 129X1/SvJ * BALB/cIco
abnormal cell death J:54177
abnormal intersomitic vessel morphology J:54177
abnormal umbilical artery morphology J:54177
abnormal umbilical cord blood vessel morphology J:54177
abnormal vasculogenesis J:54177
abnormal visceral yolk sac blood island morphology J:54177
absent vitelline blood vessels J:54177
decreased angiogenesis J:54177
dilated dorsal aorta J:54177
distended pericardium J:54177
embryonic growth retardation J:54177
embryonic lethality during organogenesis, complete penetrance J:54177
incomplete embryo turning J:54177
incomplete somite formation J:54177
irregular heartbeat J:54177
pallor J:54177
Cdh5tm1Pec/Cdh5tm1Pec
Not Specified
abnormal angiogenesis J:56509
abnormal cardiac outflow tract development J:56509
abnormal intersomitic vessel morphology J:56509
abnormal placenta vasculature J:56509
abnormal somite development J:56509
abnormal vascular development J:56509
abnormal vascular endothelial cell development J:56509
abnormal vasculogenesis J:56509
abnormal vein development J:56509
abnormal vitelline vasculature morphology J:56509
delayed heart development J:56509
embryonic growth arrest J:56509
embryonic lethality during organogenesis, complete penetrance J:56509
normal hematopoietic system phenotype J:56509
increased apoptosis J:56509
small pharyngeal arch J:56509
Cdh5tm2(Cdh5)Dvst/Cdh5tm2(Cdh5)Dvst
involves: 129 * C57BL/6
no abnormal phenotype detected J:177191
Cdh5tm2Pec/Cdh5tm2Pec
Not Specified
abnormal angiogenesis J:56509
abnormal cardiac outflow tract development J:56509
abnormal intersomitic vessel morphology J:56509
abnormal placenta vasculature J:56509
abnormal somite development J:56509
abnormal vascular development J:56509
abnormal vascular endothelial cell development J:56509
abnormal vasculogenesis J:56509
abnormal vein development J:56509
abnormal vitelline vasculature morphology J:56509
delayed heart development J:56509
embryonic growth arrest J:56509
embryonic lethality during organogenesis, complete penetrance J:56509
normal hematopoietic system phenotype J:56509
increased apoptosis J:56509
small pharyngeal arch J:56509
Cdh5tm3(Cdh5/Ctnna1)Dvst/Cdh5tm3(Cdh5/Ctnna1)Dvst
B6.Cg-Cdh5tm3(Cdh5/Ctnna1)Dvst
abnormal common myeloid progenitor cell morphology J:213676
abnormal definitive hematopoiesis J:213676
abnormal hematopoietic stem cell physiology J:213676
abnormal lymphatic vessel endothelium morphology J:213676
abnormal lymphatic vessel morphology J:213676
normal cardiovascular system phenotype J:213676
decreased liver weight J:213676
embryonic lethality during organogenesis, incomplete penetrance J:213676
embryonic lethality, complete penetrance J:177191
increased hematopoietic precursor cell number J:213676
lethality throughout fetal growth and development, complete penetrance J:213676
liver hypoplasia J:213676
lymphedema J:213676
small liver J:213676
Cdh5tm3(Cdh5/Ctnna1)Dvst/Cdh5tm3(Cdh5/Ctnna1)Dvst
involves: 129 * C57BL/6
abnormal cellular extravasation J:177191
abnormal leukocyte migration J:177191
abnormal lymphatic vessel endothelial cell morphology J:213676
abnormal skin physiology J:177191
abnormal vascular permeability J:177191
normal immune system phenotype J:213676
increased leukocyte cell number J:177191
increased neutrophil cell number J:177191
preweaning lethality, incomplete penetrance J:177191
Cdh5tm5Dvst/Cdh5tm5Dvst
B6.Cg-Cdh5tm5Dvst
abnormal cellular extravasation J:209801
Cdh5tm6Dvst/Cdh5tm6Dvst
B6.Cg-Cdh5tm6Dvst
abnormal cellular extravasation J:209801
Cdh5tm7Dvst/Cdh5tm7Dvst
Not Specified
embryonic lethality during organogenesis, complete penetrance J:213676
Cdh5tm8Dvst/Cdh5tm8Dvst
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: C57BL/10 * CBA/Ca
normal liver/biliary system phenotype J:213676

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory