Jarid2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Jarid2
jumonji and AT-rich interaction domain containing 2
MGI:104813

56 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Jarid2^{Gt(pGT1.8geo)6Pgr}/Jarid2^{Gt(pGT1.8geo)6Pgr} either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)	abnormal nervous system development	J:47982
	edema	J:47982
	prenatal lethality	J:47982
Jarid2^Gt(ROSA)1Gel/Jarid2^Gt(ROSA)1Gel involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal coronary vessel morphology	J:63359
	abnormal fetal cardiomyocyte proliferation	J:100923
	abnormal interventricular groove morphology	J:63359
	abnormal interventricular septum morphology	J:63359
	abnormal myocardium compact layer morphology	J:63359
	abnormal myocardium layer morphology	J:63359
	abnormal sternum morphology	J:63359
	abnormal thoracic cage morphology	J:63359
	decreased embryo size	J:63359
	dilated heart right atrium	J:63359
	double outlet right ventricle	J:63359
	edema	J:63359
	perinatal lethality, complete penetrance	J:63359
	respiratory failure	J:63359
	thin myocardium	J:63359
	trabecula carnea hypoplasia	J:63359
	ventricular septal defect	J:63359
Jarid2^jumonji/Jarid2^jumonji C3.129P2-Jarid2^jumonji	abnormal heart development	J:57069
	abnormal heart left ventricle morphology	J:57069
	abnormal myocardial fiber morphology	J:57069
	abnormal myocardial trabeculae morphology	J:57069
	abnormal neural plate morphology	J:57069
	abnormal neural tube morphology	J:57069
	decreased embryo size	J:57069
	delayed neural tube closure	J:57069
	embryonic lethality during organogenesis, complete penetrance	J:57069
	incomplete rostral neuropore closure	J:57069
Jarid2^jumonji/Jarid2^jumonji C.129P2-Jarid2^jumonji	abnormal definitive hematopoiesis	J:51843
	abnormal erythropoiesis	J:51843
	abnormal liver morphology	J:42772
	abnormal liver physiology	J:85152
	abnormal megakaryocyte progenitor cell morphology	J:68443
	abnormal splenic cell ratio	J:42772
	abnormal thymus cell ratio	J:42772
	anemia	J:51843
	decreased fetal derived definitive erythrocyte cell number	J:51843
	decreased hepatocyte number	J:85152
	dilated liver sinusoidal space	J:42772
	distended pericardium	J:42772
	edema	J:42772
	fetal growth retardation	J:42772
	hemorrhage	J:42772
	hepatic necrosis	J:42772
	lethality throughout fetal growth and development, complete penetrance	J:42772
	liver hypoplasia	J:42772
	normal nervous system phenotype	J:42772
	small liver	J:85152
	spleen hypoplasia	J:42772
	thymus hypoplasia	J:42772
Jarid2^jumonji/Jarid2^jumonji either: B6.129P2-Jarid2^jumonji or D2.129P2-Jarid2^jumonji	edema	J:42772
	lethality throughout fetal growth and development, complete penetrance	J:42772
	liver hypoplasia	J:42772
	normal nervous system phenotype	J:42772
	spleen hypoplasia	J:42772
	thymus hypoplasia	J:42772
Jarid2^jumonji/Jarid2^jumonji involves: 129P2/OlaHsd * BALB/cA	abnormal nervous system development	J:25641
	abnormal neural fold formation	J:25641
	abnormal neural tube closure	J:25641
	delayed neural tube closure	J:25641
	edema	J:25641
	embryonic lethality during organogenesis, incomplete penetrance	J:25641
	lethality throughout fetal growth and development, incomplete penetrance	J:25641
Jarid2^{tm1a(KOMP)Wtsi}/Jarid2⁺ Not Specified	increased body length	J:165965
Jarid2^{tm1a(KOMP)Wtsi}/Jarid2⁺ Not Specified	increased circulating creatinine level	J:175295
Jarid2^tm1Yskl/Jarid2^tm1Yskl Tg(Myh6-cre)2182Mds/0 involves: 129S1/Sv * 129X1/SvJ * FVB/N	no abnormal phenotype detected	J:114450

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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