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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Runx3
runt related transcription factor 3
MGI:102672
18 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dynlrb1tm1c(EUCOMM)Wtsi/Dynlrb1tm1c(EUCOMM)Wtsi
Runx3tm6(EGFP/cre)Yg/Runx3+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6N 		abnormal gait J:292124
abnormal motor coordination/balance J:292124
abnormal proprioceptive neuron morphology J:292124
decreased locomotor activity J:292124
impaired balance J:292124
limb grasping J:292124
normal nervous system phenotype J:292124
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Runx1tm1Toku/Runx1tm1Toku
Runx3tm1Itan/Runx3tm1Itan
Tg(Cd4-cre)1Cwi/0
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/2 		abnormal interferon secretion J:131081
increased CD4-positive, alpha-beta T cell number J:131081
Runx1tm1Tani/Runx1tm1Tani
Runx3tm1Itan/Runx3tm1Itan
Tg(Cd4-cre)1Cwi/?
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		decreased CD8-positive, alpha-beta T cell number J:125959
Runx1tm1Toku/Runx1+
Runx3tm1Itan/Runx3tm1Itan
Tg(Cd4-cre)1Cwi/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		decreased CD8-positive, alpha-beta T cell number J:131081
Runx1tm1Toku/Runx1tm1Toku
Runx3tm1Itan/Runx3+
Tg(Cd4-cre)1Cwi/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		decreased CD4-positive, alpha-beta T cell number J:131081
decreased CD8-positive, alpha-beta T cell number J:131081
Runx1tm1Toku/Runx1tm1Toku
Runx3tm1Itan/Runx3tm1Itan
Tg(Cd4-cre)1Cwi/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		decreased CD4-positive, alpha-beta T cell number J:131081
decreased CD8-positive, alpha-beta T cell number J:131081
Runx2tm1Mjo/Runx2+
Runx3tm1Yg/Runx3tm1Yg
involves: 129S1/Sv * 129X1/SvJ * ICR 		delayed bone ossification J:224290
postnatal lethality, incomplete penetrance J:224290
Runx2tm1Mjo/Runx2+
Runx3tm3Yg/Runx3tm3Yg
Tg(Col1a1-cre)1Kry/0
involves: FVB/N 		decreased body height J:224290
decreased body size J:224290
Runx3tm1.1Itok/Runx3tm1.1Itok
Trp53tm1Brn/Trp53tm1Brn
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129P2/OlaHsd * C57BL/6 * CD-1 		decreased osteosarcoma incidence J:319454
increased tumor-free survival time J:319454
Runx3tm1Itan/Runx3+
Trp53tm1Brn/Trp53tm1Brn
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129P2/OlaHsd * C57BL/6 * CD-1 		decreased osteosarcoma incidence J:319454
increased tumor-free survival time J:319454
Runx3tm1Itan/Runx3tm1Itan
Trp53tm1Brn/Trp53tm1Brn
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129P2/OlaHsd * C57BL/6 * CD-1 		premature death J:319454
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory