Hba
Complex/Cluster/Region Detail

Symbol Name ID

Hba hemoglobin alpha chain complex MGI:96014

Feature Type

complex/cluster/region

Genetic Map

Chromosome 11
cytoband A

Mapping data(79)

Alleles and phenotypes

All alleles(15) : Targeted(10) Chemically induced(3) Radiation induced(2)
 

Mice homozygous for one knock-out allele exhibit lethality during fetal development, reduced size and anemia. Mice homozygous for another knock-out allele exhibit preweaning lethality, pallor and anemia.

 
Human Diseases Modeled Using Mouse Hba (5)   

Expression

Literature Summary: (18 records)
Data Summary: Results (16)    Tissues (15)   
Theiler Stages: 10, 18, 20, 21, 23, 25, 28

Assay Type	Results
Northern blot	12
RNase protection	2
Nuclease S1	2

Molecular reagents

All nucleic(22) Genomic(9) cDNA(4) Other(9)

Other database links

Entrez Gene

15121

Polymorphisms

RFLP(5) : SNPs(0 from dbSNP Build 128)

References

(Earliest) J:107 POPP RA, Studies on the mouse hemoglobin loci. II. Position of the hemoglobin locus with respect to albinism and shaker-1 loci. J Hered. 1962 Mar-Apr;53:73-80
(Latest) J:192837 Hanson MS, et al., A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia. Am J Physiol Heart Circ Physiol. 2013 Jan 15;304(2):H328-36
All references(177)

Other accession IDs

MGD-MRK-10623