Rr353 Other Genome Feature Detail

Summary

• Symbol
  Rr353
• Name
  regulatory region 353
• Synonyms
  MCS-R4, R4

• Feature Type
  enhancer
• IDs
  MGI:7432965
• Member of
  Rr350 cluster
• Regulates expression of
  Hba (1 regulated gene)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 11, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Genomic Mutations
  1 involving Rr353
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 5

  Phenotypes 2
• Earliest
  J:184965 Kowalczyk MS, et al., Intragenic enhancers act as alternative promoters. Mol Cell. 2012 Feb 24;45(4):447-58
• Latest
  J:366854 Kassouf MT, et al., The alpha-globin super-enhancer acts in an orientation-dependent manner. Nat Commun. 2025 Jan 25;16(1):1033

Rr353 regulates expression of:

Feature	Feature Type	Location	Reference
Hba, hemoglobin alpha chain complex	complex/cluster/region	Chr11, cytoband A	J:184965