Hba Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hba
hemoglobin alpha chain complex
MGI:96014

45 phenotypes from 12 alleles in 14 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Hba^b2(th)/\Hba⁺ either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC)	acanthocytosis	J:86011
	anisocytosis	J:123943
	anisopoikilocytosis	J:86011
	dacryocytosis	J:86011
	decreased hematocrit	J:123943
	decreased hemoglobin content	J:123943
	decreased mean corpuscular hemoglobin	J:123943
	decreased mean corpuscular volume	J:123943
	hypochromic microcytic anemia	J:123943
	increased erythrocyte cell number	J:123943
	increased leukocyte cell number	J:123943
	leptocytosis	J:86011
	microcytosis	J:123943
	poikilocytosis	J:86011
	reticulocytosis	J:123943
\Hba^b2(th)/\Hba⁺ involves: 101/Rl * SEC/Rl	abnormal hemoglobin	J:5686
	increased erythrocyte clearance	J:150481
	premature death	J:150481
\Hba^b2(th)/\Hba⁺ involves: C57BL/6J * SEC	postnatal lethality	J:32654
\Hba^b2(th)/\Hba⁺ SEC-Hba^b2(th)	abnormal fetal derived definitive erythrocyte morphology	J:6452
\Hba^b2(th)/\Hba⁺ SEC-Hba^b2(th)	normal growth/size/body region phenotype	J:6452
\Hba^b2(th)/\Hba^b2(th) SEC-Hba^b2(th)	embryonic growth retardation	J:6452
	embryonic lethality between implantation and somite formation, incomplete penetrance	J:6452
	trophectoderm cell degeneration	J:6452
\Hba^b3(th)/\Hba⁺ either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC)	acanthocytosis	J:86011
	anisocytosis	J:123943
	anisopoikilocytosis	J:86011
	dacryocytosis	J:86011
	decreased hematocrit	J:123943
	decreased hemoglobin content	J:123943
	decreased mean corpuscular hemoglobin	J:123943
	decreased mean corpuscular volume	J:123943
	hypochromic microcytic anemia	J:123943
	increased erythrocyte cell number	J:123943
	leptocytosis	J:86011
	microcytosis	J:123943
	poikilocytosis	J:86011
	reticulocytosis	J:123943
\Hba^b3(th)/\Hba⁺ involves: 101 * SEC	abnormal hemoglobin	J:5686
\Hba^b3(th)/\Hba⁺ involves: C57BL/6J * SEC	postnatal lethality	J:32654
\Hba^b3(th)/\Hba⁺ SEC-Hba^b3(th)	abnormal fetal derived definitive erythrocyte morphology	J:6452
	decreased birth body size	J:6452
	decreased body weight	J:6452
	postnatal lethality, incomplete penetrance	J:6452
\Hba^b3(th)/\Hba^b3(th) SEC-Hba^b3(th)	embryonic growth retardation	J:6452
	embryonic lethality between implantation and somite formation, incomplete penetrance	J:6452
	trophectoderm cell degeneration	J:6452
\Hba^c2/\Hba^c2 involves: C3H/HeH	no abnormal phenotype detected	J:185113
\Hba^g2/\Hba^g2 involves: C57BL/6J * DBA/2J	no abnormal phenotype detected	J:7188
\Hba^th-J/\Hba⁺ B6.Cg-Hba^th-J	maternal effect	J:29127
\Hba^th-J/\Hba⁺ involves: C57BL/6J	decreased body weight	J:45721
	decreased hemoglobin content	J:45721
	increased erythrocyte cell number	J:45721
	microcytosis	J:45721
	postnatal lethality	J:32654
\Hba^th-J/\Hba^th-J involves: C57BL/6J	abnormal blastocyst morphology	J:29665
	abnormal inner cell mass morphology	J:29665
	abnormal trophectoderm morphology	J:29665
	embryonic lethality between implantation and somite formation, complete penetrance	J:29665
\Hba^tm1.1Ney/\Hba^tm1.1Ney either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ)	no abnormal phenotype detected	J:86682
\Hba^tm1Ney/\Hba^tm1Ney either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ)	abnormal erythrocyte morphology	J:86682
	anemia	J:86682
	anisopoikilocytosis	J:86682
	decreased hemoglobin content	J:86682
	decreased mean corpuscular hemoglobin	J:86682
	decreased mean corpuscular volume	J:86682
	hydrops fetalis	J:86682
	increased erythrocyte cell number	J:86682
	leptocytosis	J:86682
	pallor	J:86682
	preweaning lethality, incomplete penetrance	J:86682
	reticulocytosis	J:86682
	schistocytosis	J:86682
\Hba^tm1Paz/\Hba⁺ involves: 129S7/SvEvBrd	decreased hemoglobin content	J:117887
	decreased mean corpuscular hemoglobin	J:117887
	decreased mean corpuscular volume	J:117887
	reticulocytosis	J:117887
\Hba^tm1Paz/\Hba^tm1Paz involves: 129S7/SvEvBrd	abnormal erythrocyte morphology	J:28392
	decreased fetal size	J:28392
	decreased mean corpuscular hemoglobin	J:28392
	decreased mean corpuscular volume	J:28392
	hydrops fetalis	J:28392
	lethality throughout fetal growth and development, complete penetrance	J:28392
\Rhbdf1/Hba^{tm1(RHBDF1/HBA)Ajhs}/\Hba⁺ involves: 129P2/OlaHsd * C57BL/6 * CBA	anisopoikilocytosis	J:117887
\Rhbdf1/Hba^{tm1(RHBDF1/HBA)Ajhs}/\Rhbdf1/Hba^{tm1(RHBDF1/HBA)Ajhs} involves: 129P2/OlaHsd * C57BL/6 * CBA	anisopoikilocytosis	J:117887
	decreased hemoglobin content	J:117887
	decreased mean corpuscular hemoglobin	J:117887
	decreased mean corpuscular volume	J:117887
	microcytosis	J:117887
	neonatal lethality, incomplete penetrance	J:117887
	prenatal lethality, incomplete penetrance	J:117887
	reticulocytosis	J:117887
\Rhbdf1/Hba^{tm1.1(RHBDF1/HBA)Ajhs}/\Rhbdf1/Hba^{tm1.1(RHBDF1/HBA)Ajhs} involves: 129P2/OlaHsd * C57BL/6 * CBA	decreased hemoglobin content	J:117887
	decreased mean corpuscular hemoglobin	J:117887
	decreased mean corpuscular volume	J:117887
	reticulocytosis	J:117887
\Rhbdf1/Hba^tm2.1Ajhs/\Hba⁺ involves: 129P2/OlaHsd * C57BL/6	decreased hemoglobin content	J:117887
	decreased mean corpuscular hemoglobin	J:117887
	decreased mean corpuscular volume	J:117887
\Rhbdf1/Hba^tm2Ajhs/\Hba⁺ involves: 129P2/OlaHsd * C57BL/6	anisopoikilocytosis	J:117887
	decreased hemoglobin content	J:117887
	decreased mean corpuscular hemoglobin	J:117887
	decreased mean corpuscular volume	J:117887
	microcytosis	J:117887
\Rhbdf1/Hba^tm2Ajhs/\Rhbdf1/Hba^tm2Ajhs involves: 129P2/OlaHsd * C57BL/6	anemia	J:117887
	decreased embryo size	J:117887
	embryonic lethality during organogenesis, complete penetrance	J:117887
	pallor	J:117887

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