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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hba
hemoglobin alpha chain complex
MGI:96014
45 phenotypes from 12 alleles in 14 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Hbab2(th)/Hba+
either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC)
acanthocytosis J:86011
anisocytosis J:123943
anisopoikilocytosis J:86011
dacryocytosis J:86011
decreased hematocrit J:123943
decreased hemoglobin content J:123943
decreased mean corpuscular hemoglobin J:123943
decreased mean corpuscular volume J:123943
hypochromic microcytic anemia J:123943
increased erythrocyte cell number J:123943
increased leukocyte cell number J:123943
leptocytosis J:86011
microcytosis J:123943
poikilocytosis J:86011
reticulocytosis J:123943
Hbab2(th)/Hba+
involves: 101/Rl * SEC/Rl
abnormal hemoglobin J:5686
increased erythrocyte clearance J:150481
premature death J:150481
Hbab2(th)/Hba+
involves: C57BL/6J * SEC
postnatal lethality J:32654
Hbab2(th)/Hba+
SEC-Hbab2(th)
abnormal fetal derived definitive erythrocyte morphology J:6452
normal growth/size/body region phenotype J:6452
Hbab2(th)/Hbab2(th)
SEC-Hbab2(th)
embryonic growth retardation J:6452
embryonic lethality between implantation and somite formation, incomplete penetrance J:6452
trophectoderm cell degeneration J:6452
Hbab3(th)/Hba+
either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC)
acanthocytosis J:86011
anisocytosis J:123943
anisopoikilocytosis J:86011
dacryocytosis J:86011
decreased hematocrit J:123943
decreased hemoglobin content J:123943
decreased mean corpuscular hemoglobin J:123943
decreased mean corpuscular volume J:123943
hypochromic microcytic anemia J:123943
increased erythrocyte cell number J:123943
leptocytosis J:86011
microcytosis J:123943
poikilocytosis J:86011
reticulocytosis J:123943
Hbab3(th)/Hba+
involves: 101 * SEC
abnormal hemoglobin J:5686
Hbab3(th)/Hba+
involves: C57BL/6J * SEC
postnatal lethality J:32654
Hbab3(th)/Hba+
SEC-Hbab3(th)
abnormal fetal derived definitive erythrocyte morphology J:6452
decreased birth body size J:6452
decreased body weight J:6452
postnatal lethality, incomplete penetrance J:6452
Hbab3(th)/Hbab3(th)
SEC-Hbab3(th)
embryonic growth retardation J:6452
embryonic lethality between implantation and somite formation, incomplete penetrance J:6452
trophectoderm cell degeneration J:6452
Hbac2/Hbac2
involves: C3H/HeH
no abnormal phenotype detected J:185113
Hbag2/Hbag2
involves: C57BL/6J * DBA/2J
no abnormal phenotype detected J:7188
Hbath-J/Hba+
B6.Cg-Hbath-J
maternal effect J:29127
Hbath-J/Hba+
involves: C57BL/6J
decreased body weight J:45721
decreased hemoglobin content J:45721
increased erythrocyte cell number J:45721
microcytosis J:45721
postnatal lethality J:32654
Hbath-J/Hbath-J
involves: C57BL/6J
abnormal blastocyst morphology J:29665
abnormal inner cell mass morphology J:29665
abnormal trophectoderm morphology J:29665
embryonic lethality between implantation and somite formation, complete penetrance J:29665
Hbatm1.1Ney/Hbatm1.1Ney
either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ)
no abnormal phenotype detected J:86682
Hbatm1Ney/Hbatm1Ney
either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ)
abnormal erythrocyte morphology J:86682
anemia J:86682
anisopoikilocytosis J:86682
decreased hemoglobin content J:86682
decreased mean corpuscular hemoglobin J:86682
decreased mean corpuscular volume J:86682
hydrops fetalis J:86682
increased erythrocyte cell number J:86682
leptocytosis J:86682
pallor J:86682
preweaning lethality, incomplete penetrance J:86682
reticulocytosis J:86682
schistocytosis J:86682
Hbatm1Paz/Hba+
involves: 129S7/SvEvBrd
decreased hemoglobin content J:117887
decreased mean corpuscular hemoglobin J:117887
decreased mean corpuscular volume J:117887
reticulocytosis J:117887
Hbatm1Paz/Hbatm1Paz
involves: 129S7/SvEvBrd
abnormal erythrocyte morphology J:28392
decreased fetal size J:28392
decreased mean corpuscular hemoglobin J:28392
decreased mean corpuscular volume J:28392
hydrops fetalis J:28392
lethality throughout fetal growth and development, complete penetrance J:28392
Rhbdf1/Hbatm1(RHBDF1/HBA)Ajhs/Hba+
involves: 129P2/OlaHsd * C57BL/6 * CBA
anisopoikilocytosis J:117887
Rhbdf1/Hbatm1(RHBDF1/HBA)Ajhs/Rhbdf1/Hbatm1(RHBDF1/HBA)Ajhs
involves: 129P2/OlaHsd * C57BL/6 * CBA
anisopoikilocytosis J:117887
decreased hemoglobin content J:117887
decreased mean corpuscular hemoglobin J:117887
decreased mean corpuscular volume J:117887
microcytosis J:117887
neonatal lethality, incomplete penetrance J:117887
prenatal lethality, incomplete penetrance J:117887
reticulocytosis J:117887
Rhbdf1/Hbatm1.1(RHBDF1/HBA)Ajhs/Rhbdf1/Hbatm1.1(RHBDF1/HBA)Ajhs
involves: 129P2/OlaHsd * C57BL/6 * CBA
decreased hemoglobin content J:117887
decreased mean corpuscular hemoglobin J:117887
decreased mean corpuscular volume J:117887
reticulocytosis J:117887
Rhbdf1/Hbatm2.1Ajhs/Hba+
involves: 129P2/OlaHsd * C57BL/6
decreased hemoglobin content J:117887
decreased mean corpuscular hemoglobin J:117887
decreased mean corpuscular volume J:117887
Rhbdf1/Hbatm2Ajhs/Hba+
involves: 129P2/OlaHsd * C57BL/6
anisopoikilocytosis J:117887
decreased hemoglobin content J:117887
decreased mean corpuscular hemoglobin J:117887
decreased mean corpuscular volume J:117887
microcytosis J:117887
Rhbdf1/Hbatm2Ajhs/Rhbdf1/Hbatm2Ajhs
involves: 129P2/OlaHsd * C57BL/6
anemia J:117887
decreased embryo size J:117887
embryonic lethality during organogenesis, complete penetrance J:117887
pallor J:117887

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory