Rr351 Other Genome Feature Detail

Summary

• Symbol
  Rr351
• Name
  regulatory region 351
• Synonyms
  MCS-R3, R3

• Feature Type
  enhancer
• IDs
  MGI:7432866
• Member of
  Rr350 cluster
• Regulates expression of
  Hba (1 regulated gene)

Location &
Maps

• Sequence Map
  Chr11:32206068-32206646 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• J:259286: chr11:32156068-32156646 (NCBIm37) chr11:32206068-32206646 (GRCm39)

• Genetic Map
  Chromosome 11, Syntenic

Strain
Comparison

• SNPs within 2kb
  89 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  3
• Targeted
  3
• Genomic Mutations
  1 involving Rr351
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 6

  Phenotypes 3
• Earliest
  J:184965 Kowalczyk MS, et al., Intragenic enhancers act as alternative promoters. Mol Cell. 2012 Feb 24;45(4):447-58
• Latest
  J:366854 Kassouf MT, et al., The alpha-globin super-enhancer acts in an orientation-dependent manner. Nat Commun. 2025 Jan 25;16(1):1033

Rr351 regulates expression of:

Feature	Feature Type	Location	Reference
Hba, hemoglobin alpha chain complex	complex/cluster/region	Chr11, cytoband A	J:184965