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Taok3 Gene Detail
Summary
  • Symbol
    Taok3
  • Name
    TAO kinase 3
  • Synonyms
    2900006A08Rik, A430105I05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041177
    NCBI Gene: 330177
  • Gene Overview
    MyGene.info: TAOK3
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:117120112-117275101 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 56.88 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1046 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041177
protein coding gene Chr5:117120112-117275219 (.)
129S1/SvImJ MGP_129S1SvImJ_G0029984
protein coding gene Chr5:120177645-120344896 (+)
A/J MGP_AJ_G0029948
protein coding gene Chr5:115309774-115465784 (+)
AKR/J MGP_AKRJ_G0029887
protein coding gene Chr5:119028898-119186534 (+)
BALB/cJ MGP_BALBcJ_G0029959
protein coding gene Chr5:116726797-116883764 (+)
C3H/HeJ MGP_C3HHeJ_G0029679
protein coding gene Chr5:119545804-119707502 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030414
protein coding gene Chr5:124750439-124929049 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027640
protein coding gene Chr5:110070603-110225686 (+)
CAST/EiJ MGP_CASTEiJ_G0029088
protein coding gene Chr5:118550068-118717795 (+)
CBA/J MGP_CBAJ_G0029647
protein coding gene Chr5:129568872-129750823 (+)
DBA/2J MGP_DBA2J_G0029797
protein coding gene Chr5:115406221-115561863 (+)
FVB/NJ MGP_FVBNJ_G0029753
protein coding gene Chr5:114258103-114416430 (+)
LP/J MGP_LPJ_G0029885
protein coding gene Chr5:120689540-120860744 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029784
protein coding gene Chr5:133812459-133978367 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030455
protein coding gene Chr5:118546748-118711654 (+)
PWK/PhJ MGP_PWKPhJ_G0028801
protein coding gene Chr5:114089442-114248100 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028639
protein coding gene Chr5:116115040-116275873 (+)
WSB/EiJ MGP_WSBEiJ_G0029163
protein coding gene Chr5:119126844-119290191 (+)



Homology
more
  • Human Ortholog
    TAOK3, TAO kinase 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TAOK3, TAO kinase 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DPK, hKFC-A, JIK, MAP3K18
  • Links
    NCBI Gene ID: 51347
    neXtProt AC: NX_Q9H2K8
    UniProt: Q9H2K8

  • Chr Location
    12q24.23; chr12:118149801-118372950 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 330177 NCBI Gene Model | MGI Sequence Detail 154990 C57BL/6J ±  kb
transcript NM_001199685 RefSeq | MGI Sequence Detail 4366 C57BL/6  
polypeptide Q8BYC6 UniProt | EBI | MGI Sequence Detail 898 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 5
Other
Accession IDs
less
MGI:1920107
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:264707 Hammad H, et al., Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10. Nat Immunol. 2017 Mar;18(3):313-320

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory