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Taok3
Gene Detail
 Symbol
Name
ID
Taok3
TAO kinase 3
MGI:3041177
Synonyms 2900006A08Rik, A430105I05Rik
Feature Type protein coding gene
Genetic Map
Chromosome 5
56.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:117120129-117275219 bp, + strand
From VEGA annotation of GRCm38

  155091 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:83279  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: serine/threonine-protein kinase TAO1
Gene Tree: Taok3

Human
homologs
Human Homolog TAOK3, TAO kinase 3
NCBI Gene ID 51347
neXtProt AC  NX_Q9H2K8
Human Synonyms  DPK, JIK, MAP3K18
Human Chr (Location)  12q; chr12:118149801-118372945 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(12)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Taok3 interacts with 292 markers (Mir1a-1, Mir1a-2, Mir10a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process activation of MAPKK activity, cellular response to DNA damage stimulus, ...
Component cytoplasm, intracellular
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (24)    Tissues (15)    Images (2)
Theiler Stages: 23
Assay TypeResults
RNA in situ 24
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(17)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000025729 (Evidence)
Ensembl Gene ModelENSMUSG00000061288 (Evidence)
Entrez Gene330177 (Evidence)
DFCITC1593144, TC1615963, TC1624937, TC1640665, TC1642705, TC1660387, TC1668538
DoTSDT.101129704, DT.101721767, DT.484691, DT.488892, DT.528373, DT.91296039, DT.91330113, DT.97365135, DT.97373974
NIA Mouse Gene IndexU042678
EC2.7.11.1
Consensus CDS ProjectCCDS39233.1
International Mouse Knockout Project StatusTaok3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025729 VEGA Gene Model | MGI Sequence Detail 155091 C57BL/6J ±  kb
transcript OTTMUST00000063363 VEGA | MGI Sequence Detail 4354 Not Applicable 
polypeptide OTTMUSP00000031319 VEGA | MGI Sequence Detail 898 Not Applicable 

For the selected sequences
All sequences(89) RefSeq(12) UniProt(6)
Polymorphisms SNPs within 2kb(1064 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000016050 serine/threonine-protein kinase TAO3
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:195683 Kapfhamer D, et al., JNK pathway activation is controlled by Tao/TAOK3 to modulate ethanol sensitivity. PLoS One. 2012;7(12):e50594
All references(34)
Other
accession IDs
MGI:1920107

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory