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Taok3
Gene Detail
Symbol

Name
ID
Taok3
TAO kinase 3
MGI:3041177
Synonyms
2900006A08Rik, A430105I05Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
56.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:117120129-117275219 bp, + strand
From VEGA annotation of GRCm38

  155091 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:83279  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: TAOK3
Protein SuperFamily: serine/threonine-protein kinase TAO1
Gene Tree: Taok3

Human
homologs
TAOK3, TAO kinase 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 51347
neXtProt AC: NX_Q9H2K8

Human Synonyms: DPK, JIK, MAP3K18

Human Chr (Location): 12q; chr12:118149801-118372945 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(12)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Taok3 interacts with 292 markers (Mir1a-1, Mir1a-2, Mir10a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process activation of MAPKK activity, cellular response to DNA damage stimulus, ...
Component cytoplasm, intracellular, ...
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (24)    Tissues (15)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase taok3    NEW 
Molecular
reagents
All nucleic(19) cDNA(19)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000025729 (Evidence)
Ensembl Gene Model ENSMUSG00000061288 (Evidence)
Entrez Gene 330177 (Evidence)
DFCI TC1642705, TC1624937, TC1640665, TC1615963, TC1593144, TC1660387, TC1668538
DoTS DT.101129704, DT.488892, DT.484691, DT.101721767, DT.91296039, DT.528373, DT.97365135, DT.91330113, DT.97373974
NIA Mouse Gene Index U042678
EC 2.7.11.1
Consensus CDS Project CCDS39233.1
International Mouse Phenotyping Consortium Status Taok3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025729 VEGA Gene Model | MGI Sequence Detail 155091 C57BL/6J ±  kb
transcript OTTMUST00000063363 VEGA | MGI Sequence Detail 4354 Not Applicable 
polypeptide OTTMUSP00000031319 VEGA | MGI Sequence Detail 898 Not Applicable 

For the selected sequences
All sequences(94) RefSeq(14) UniProt(6)
Polymorphisms
SNPs within 2kb(1064 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000016050 serine/threonine-protein kinase TAO3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:195683 Kapfhamer D, et al., JNK pathway activation is controlled by Tao/TAOK3 to modulate ethanol sensitivity. PLoS One. 2012;7(12):e50594
All references(33)
Other
accession IDs
MGI:1920107

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory