About   Help   FAQ
Slitrk2 Gene Detail
Summary
  • Symbol
    Slitrk2
  • Name
    SLIT and NTRK-like family, member 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679449
    NCBI Gene: 245450
  • Gene Overview
    MyGene.info: SLITRK2
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:66649318-66661393 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 34.81 cM, cytoband A5
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679449
protein coding gene ChrX:66649318-66661402 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035769
protein coding gene ChrX:62220429-62232508 (+)
A/J MGP_AJ_G0035751
protein coding gene ChrX:62379326-62392039 (+)
AKR/J MGP_AKRJ_G0035671
protein coding gene ChrX:64117828-64131029 (+)
BALB/cJ MGP_BALBcJ_G0035738
protein coding gene ChrX:61685754-61701484 (+)
C3H/HeJ MGP_C3HHeJ_G0035441
protein coding gene ChrX:62722970-62735003 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036270
protein coding gene ChrX:64061982-64075191 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033119
protein coding gene ChrX:61692606-61704657 (+)
CAST/EiJ MGP_CASTEiJ_G0034733
protein coding gene ChrX:48278373-48290491 (+)
CBA/J MGP_CBAJ_G0035415
protein coding gene ChrX:65874774-65887046 (+)
DBA/2J MGP_DBA2J_G0035569
protein coding gene ChrX:61936002-61947715 (+)
FVB/NJ MGP_FVBNJ_G0035519
protein coding gene ChrX:61443844-61455833 (+)
LP/J MGP_LPJ_G0035657
protein coding gene ChrX:63006957-63019023 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035555
protein coding gene ChrX:67940754-67949511 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036289
protein coding gene ChrX:62102136-62114191 (+)
PWK/PhJ MGP_PWKPhJ_G0034431
protein coding gene ChrX:46506353-46526994 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034272
protein coding gene ChrX:49236864-49249877 (+)
WSB/EiJ MGP_WSBEiJ_G0034876
protein coding gene ChrX:61520659-61532730 (+)



Homology
more
  • Human Ortholog
    SLITRK2, SLIT and NTRK like family member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLITRK2, SLIT and NTRK like family member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CXorf1, CXorf2, SLITL1, TMEM257
  • Links
    NCBI Gene ID: 84631
    neXtProt AC: NX_Q9H156
    UniProt: Q9H156

  • Chr Location
    Xq27.3; chrX:145817829-145829856 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036790 Ensembl Gene Model | MGI Sequence Detail 12076 C57BL/6J ±  kb
transcript ENSMUST00000036043 Ensembl | MGI Sequence Detail 2992 Not Applicable  
polypeptide ENSMUSP00000044094 Ensembl | MGI Sequence Detail 846 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 11
    Other 2

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Developmental Gene Expression 7
    Gene Ontology 8
    Phenotypes 2
  • Earliest
    J:85959 Aruga J, et al., Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth. Mol Cell Neurosci. 2003 Sep;24(1):117-29
  • Latest
    J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory