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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Slitrk2
SLIT and NTRK-like family, member 2
MGI:2679449
30 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Slitrk2em1(IMPC)Mbp/Y
C57BL/6NCrl-Slitrk2em1(IMPC)Mbp/Mmucd
decreased thigmotaxis J:211773
increased exploration in new environment J:211773
increased heart weight J:211773
Slitrk2em1(IMPC)Mbp/Slitrk2em1(IMPC)Mbp
C57BL/6NCrl-Slitrk2em1(IMPC)Mbp/Mmucd
abnormal ovary morphology J:211773
abnormal uterus morphology J:211773
enlarged ovary J:211773
enlarged uterus J:211773
increased exploration in new environment J:211773
Slitrk2tm1.1Jaru/Slitrk2tm1.1Jaru
B6.129P2-Slitrk2tm1.1Jaru
abnormal dopamine level J:326787
abnormal excitatory postsynaptic potential J:326787
abnormal serotonergic neuron morphology J:326787
abnormal serotonin level J:326787
abnormal sucrose solution preference J:326787
abnormal synapse morphology J:326787
abnormal vestibuloocular reflex J:326787
decreased exploration in new environment J:326787
enhanced coordination J:326787
hyperactivity J:326787
impaired cued conditioning behavior J:326787
increased coping response J:326787
increased thigmotaxis J:326787
normal nervous system phenotype J:326787
Slitrk2tm1.1Jwum/Y
involves: C57BL/6J
abnormal miniature excitatory postsynaptic currents J:342291
abnormal postsynaptic density morphology J:342291
abnormal spatial reference memory J:342291
Slitrk2tm1.1Jwum/Y
Tg(Nes-cre)1Atp/0
involves: C57BL/6J * FVB/N
abnormal excitatory synapse morphology J:342291
abnormal gait J:342291
abnormal long-term spatial reference memory J:342291
abnormal miniature excitatory postsynaptic currents J:342291
abnormal postsynaptic density morphology J:342291
decreased anxiety-related response J:342291
decreased body weight J:342291
impaired spatial learning J:342291

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory