About   Help   FAQ
Fem1c Gene Detail
Summary
  • Symbol
    Fem1c
  • Name
    fem 1 homolog c
  • Synonyms
    2610312A07Rik, 3632443A22Rik, mKIAA1785
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444737
    NCBI Gene: 240263
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:46504606-46525971 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 24.62 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444737
 protein coding gene Chr18:46501746-46525971 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024407
 protein coding gene Chr18:45304664-45331236 (-)
A/J MGP_AJ_G0024374
 protein coding gene Chr18:43669351-43695920 (-)
AKR/J MGP_AKRJ_G0024343
 protein coding gene Chr18:44858207-44892082 (-)
BALB/cJ MGP_BALBcJ_G0024374
 protein coding gene Chr18:43779842-43804645 (-)
C3H/HeJ MGP_C3HHeJ_G0024141
 protein coding gene Chr18:44963358-44988024 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024818
 protein coding gene Chr18:46902599-46929702 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022253
 protein coding gene Chr18:43501487-43524556 (-)
CAST/EiJ MGP_CASTEiJ_G0023615
 protein coding gene Chr18:44919565-44945374 (-)
CBA/J MGP_CBAJ_G0024110
 protein coding gene Chr18:48160457-48190203 (-)
DBA/2J MGP_DBA2J_G0024240
 protein coding gene Chr18:43290132-43314206 (-)
FVB/NJ MGP_FVBNJ_G0024206
 protein coding gene Chr18:42853827-42879810 (-)
LP/J MGP_LPJ_G0024324
 protein coding gene Chr18:45374256-45400415 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024237
 protein coding gene Chr18:49517253-49544084 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024865
 protein coding gene Chr18:44782905-44813343 (-)
PWK/PhJ MGP_PWKPhJ_G0023359
 protein coding gene Chr18:43429950-43454371 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023164
 protein coding gene Chr18:44944913-44968087 (-)
WSB/EiJ MGP_WSBEiJ_G0023678
 protein coding gene Chr18:44685519-44715240 (-)



Homology
more
  • Human Ortholog
    FEM1C, fem-1 homolog C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FEM1C, fem-1 homolog C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EUROIMAGE686608, EUROIMAGE783647, FEM1A
  • Links
    NCBI Gene ID: 56929
    neXtProt AC: NX_Q96JP0
    UniProt: Q96JP0

  • Chr Location
    5q22.3; chr5:115520908-115544919 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 10606
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FEM1C
  • Gene Tree
    Fem1c
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    8 phenotype references
Homozygous mutant mice are fertile and show no overt abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    668
  • Tissues
    37
  • cDNA Data
    13
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 240263 NCBI Gene Model | MGI Sequence Detail 21366 C57BL/6J ±  kb
transcript NM_173423 RefSeq | MGI Sequence Detail 2866 C57BL/6  
polypeptide Q8CEF1 UniProt | EBI | MGI Sequence Detail 617 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 6
Other
Accession IDs
less
MGI:1914424, MGI:2147251
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:196753 Pelzel HR, et al., Silencing of Fem1cR3 gene expression in the DBA/2J mouse precedes retinal ganglion cell death and is associated with histone deacetylase activity. Invest Ophthalmol Vis Sci. 2012 Mar;53(3):1428-35
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
04/13/2021
MGI 6.16 		The Jackson Laboratory