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Tbc1d24
Gene Detail
 Symbol
Name
ID
Tbc1d24
TBC1 domain family, member 24
MGI:2443456
Synonyms C530046L02Rik, mKIAA1171
Feature Type protein coding gene
Genetic Map
Chromosome 17
12.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:24175431-24205562 bp, - strand
From NCBI annotation of GRCm38

  30132 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:27469  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tbc1d24

Human
homologs
Human Homolog TBC1D24, TBC1 domain family, member 24
NCBI Gene ID 57465
neXtProt AC  NX_Q9ULP9
Human Synonyms  DFNA65, DFNB86, DOORS, EIEE16, FIME, TLDC6
Human Chr (Location)  16p13.3; chr16:2475132-2505733 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TBC1D24
Mutations,
alleles, and
phenotypes
All mutations/alleles(89) : Gene trapped(87) Targeted(2)
Incidental mutations (data from APF )
Interactions
Tbc1d24 interacts with 433 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process neuron projection development, regulation of Rab GTPase activity
Component cytoplasm
Function GTPase activator activity, Rab GTPase activator activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (103)    Tissues (10)    Images (23)
Theiler Stages: 23
Assay TypeResults
RNA in situ 103
cDNA source data(40)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(40) cDNA(40)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000036473 (Evidence)
Entrez Gene224617 (Evidence)
UniGene301585
DFCITC1579490, TC1591779, TC1598165, TC1614427, TC1683552
DoTSDT.101737016, DT.110552266, DT.110552288, DT.40178875, DT.60100914, DT.91332326, DT.91556966, DT.91582474, DT.94190770, DT.94237229
Consensus CDS ProjectCCDS28477.1, CCDS50012.1
International Mouse Knockout Project StatusTbc1d24
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 224617 NCBI Gene Model | MGI Sequence Detail 30132 C57BL/6J ±  kb
transcript NM_001163852 RefSeq | MGI Sequence Detail 7946 C57BL/6 
polypeptide Q3UUG6 UniProt | EBI | MGI Sequence Detail 561 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(16) UniProt(2)
Polymorphisms SNPs within 2kb(273 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000195 Rab-GTPase-TBC domain
InterPro IPR006571 TLDc
Protein Ontology PR:000016108 TBC1 domain family member 24
Graphical View of Protein Domain Structure
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory