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Tbc1d24 Gene Detail
Summary
  • Symbol
    Tbc1d24
  • Name
    TBC1 domain family, member 24
  • Synonyms
    C530046L02Rik, mKIAA1171
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443456
    NCBI Gene: 224617
  • Gene Overview
    MyGene.info: TBC1D24
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:24175431-24205562 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 12.30 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    270 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443456
protein coding gene Chr17:24175431-24209387 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023292
protein coding gene Chr17:23130821-23167456 (-)
A/J MGP_AJ_G0023252
protein coding gene Chr17:22528018-22564781 (-)
AKR/J MGP_AKRJ_G0023219
protein coding gene Chr17:22590785-22629145 (-)
BALB/cJ MGP_BALBcJ_G0023257
protein coding gene Chr17:22705305-22740120 (-)
C3H/HeJ MGP_C3HHeJ_G0023017
protein coding gene Chr17:22930815-22968989 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023700
protein coding gene Chr17:24174308-24208154 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021177
protein coding gene Chr17:19986991-20019923 (-)
CAST/EiJ MGP_CASTEiJ_G0022519
protein coding gene Chr17:22767851-22803969 (-)
CBA/J MGP_CBAJ_G0022993
protein coding gene Chr17:25000898-25037292 (-)
DBA/2J MGP_DBA2J_G0023122
protein coding gene Chr17:22101507-22135792 (-)
FVB/NJ MGP_FVBNJ_G0023092
protein coding gene Chr17:21818019-21854605 (-)
LP/J MGP_LPJ_G0023199
protein coding gene Chr17:23447383-23482350 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023111
protein coding gene Chr17:24722822-24757084 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023738
protein coding gene Chr17:22858311-22894958 (-)
PWK/PhJ MGP_PWKPhJ_G0022268
protein coding gene Chr17:20860667-20895197 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022087
protein coding gene Chr17:20882340-20918762 (-)
WSB/EiJ MGP_WSBEiJ_G0022582
protein coding gene Chr17:22926195-22962820 (-)



Homology
more
  • Human Ortholog
    TBC1D24, TBC1 domain family member 24
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TBC1D24, TBC1 domain family member 24
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DFNA65, DFNB86, DOORS, EIEE16, FIME, TLDC6
  • Links
    NCBI Gene ID: 57465
    neXtProt AC: NX_Q9ULP9
    UniProt: Q9ULP9

  • Chr Location
    16p13.3; chr16:2475104-2509669 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    3 with human TBC1D24 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 224617 NCBI Gene Model | MGI Sequence Detail 30132 C57BL/6J ±  kb
transcript NM_001163852 RefSeq | MGI Sequence Detail 7946 C57BL/6  
polypeptide NP_001157321 RefSeq | MGI Sequence Detail 561 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 43
    cDNA 41
    Primer pair 1
    Other 1

    Microarray probesets 5
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:230923 Finelli MJ, et al., The Evolutionarily Conserved Tre2/Bub2/Cdc16 (TBC), Lysin Motif (LysM), Domain Catalytic (TLDc) Domain Is Neuroprotective against Oxidative Stress. J Biol Chem. 2016 Feb 5;291(6):2751-63

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory