Sequence Detail

ID/Version

Q3UUG6 Q3TTZ8 Q6ZPW4 Q8BH92 Q8C3W8 Q8BNF2 A5D6Q7 Q3UH11 Q8C3C6 (UniProt | EBI)

Last sequence update: 2007-05-29
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=TBC1 domain family member 24;

Provider

SWISS-PROT

Sequence

Polypeptide 561 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tbc1d24	TBC1 domain family, member 24	44	101	3	33

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:230923 Finelli MJ, et al., The Evolutionarily Conserved Tre2/Bub2/Cdc16 (TBC), Lysin Motif (LysM), Domain Catalytic (TLDc) Domain Is Neuroprotective against Oxidative Stress. J Biol Chem. 2016 Feb 5;291(6):2751-63
J:271632 Finelli MJ, et al., The epilepsy-associated protein TBC1D24 is required for normal development, survival and vesicle trafficking in mammalian neurons. Hum Mol Genet. 2019 Feb 15;28(4):584-597
J:273646 Tona R, et al., The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy. Hum Mol Genet. 2019 May 1;28(9):1530-1547
J:284936 Lin L, et al., The epilepsy and intellectual disability-associated protein TBC1D24 regulates the maintenance of excitatory synapses and animal behaviors. PLoS Genet. 2020 Jan;16(1):e1008587
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:327808 Eaton AF, et al., The evolutionary conserved TLDc domain defines a new class of (H(+))V-ATPase interacting proteins. Sci Rep. 2021 Nov 22;11(1):22654
J:360774 Pepe S, et al., TBC1D24 interacts with the v-ATPase and regulates intraorganellar pH in neurons. iScience. 2025 Jan 17;28(1):111515