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Tmem270 Gene Detail
Summary
  • Symbol
    Tmem270
  • Name
    transmembrane protein 270
  • Synonyms
    1700111I05Rik, Wbscr28
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923879
    NCBI Gene: 76629
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:134930447-134935587 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 74.88 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923879
protein coding gene Chr5:134930447-134935587 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030164
protein coding gene Chr5:139361978-139367118 (-)
A/J MGP_AJ_G0030132
protein coding gene Chr5:133424454-133429500 (-)
AKR/J MGP_AKRJ_G0030065
protein coding gene Chr5:137766051-137770782 (-)
BALB/cJ MGP_BALBcJ_G0030142
protein coding gene Chr5:134779046-134784312 (-)
C3H/HeJ MGP_C3HHeJ_G0029858
protein coding gene Chr5:138318678-138323660 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030595
protein coding gene Chr5:144593002-144597413 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027819
protein coding gene Chr5:127718069-127722855 (-)
CAST/EiJ MGP_CASTEiJ_G0029267
protein coding gene Chr5:137745123-137752227 (-)
CBA/J MGP_CBAJ_G0029828
protein coding gene Chr5:150251163-150258025 (-)
DBA/2J MGP_DBA2J_G0029979
protein coding gene Chr5:133319666-133325139 (-)
FVB/NJ MGP_FVBNJ_G0029934
protein coding gene Chr5:132451378-132456423 (-)
LP/J MGP_LPJ_G0030067
protein coding gene Chr5:139828530-139833670 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029966
protein coding gene Chr5:153273164-153280779 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030635
protein coding gene Chr5:137497224-137502364 (-)
PWK/PhJ MGP_PWKPhJ_G0028982
protein coding gene Chr5:132361635-132367266 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028817
protein coding gene Chr5:135071708-135076031 (-)
WSB/EiJ MGP_WSBEiJ_G0029341
protein coding gene Chr5:138250829-138255966 (-)



Homology
more
  • Human Ortholog
    TMEM270, transmembrane protein 270
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM270, transmembrane protein 270
  • Synonyms
    WBSCR28
  • Links
    NCBI Gene ID: 135886
    neXtProt AC: NX_Q6UE05
    UniProt: Q6UE05

  • Chr Location
    7q11.23; chr7:73860848-73865893 (+)  GRCh38.p7

Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Male mice homozygous for a null allele exhibit normal fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76629 NCBI Gene Model | MGI Sequence Detail 5141 C57BL/6J ±  kb
transcript NM_029681 RefSeq | MGI Sequence Detail 933 C57BL/6  
polypeptide Q6UJB9 UniProt | EBI | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Diseases 2
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:330002 Navarro-Romero A, et al., Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams-Beuren syndrome. Elife. 2022 Oct 11;11:e72560

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory