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Psd Gene Detail
Summary
  • Symbol
    Psd
  • Name
    pleckstrin and Sec7 domain containing
  • Synonyms
    1110007H17Rik, Efa6, Efa6a, Psdl
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920978
    NCBI Gene: 73728
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:46312087-46327156 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 38.80 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    41 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920978
protein coding gene Chr19:46312085-46327188 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025204
protein coding gene Chr19:45993046-46008122 (-)
A/J MGP_AJ_G0025180
protein coding gene Chr19:43728823-43743896 (-)
AKR/J MGP_AKRJ_G0025149
protein coding gene Chr19:45145713-45160807 (-)
BALB/cJ MGP_BALBcJ_G0025175
protein coding gene Chr19:43787728-43802795 (-)
C3H/HeJ MGP_C3HHeJ_G0024935
protein coding gene Chr19:45313389-45328465 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025618
protein coding gene Chr19:47143301-47159908 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023032
protein coding gene Chr19:42967528-42982603 (-)
CAST/EiJ MGP_CASTEiJ_G0024400
protein coding gene Chr19:45110713-45128575 (-)
CBA/J MGP_CBAJ_G0024915
protein coding gene Chr19:49499733-49514830 (-)
DBA/2J MGP_DBA2J_G0025047
protein coding gene Chr19:43552216-43567358 (-)
FVB/NJ MGP_FVBNJ_G0025008
protein coding gene Chr19:43329233-43344314 (-)
LP/J MGP_LPJ_G0025133
protein coding gene Chr19:45903756-45918835 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025039
protein coding gene Chr19:48842146-48857223 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025676
protein coding gene Chr19:45253470-45268557 (-)
PWK/PhJ MGP_PWKPhJ_G0024149
protein coding gene Chr19:43498591-43513775 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023953
protein coding gene Chr19:43906186-43921268 (-)
WSB/EiJ MGP_WSBEiJ_G0024470
protein coding gene Chr19:45395091-45410160 (-)



Homology
more
  • Human Ortholog
    PSD, pleckstrin and Sec7 domain containing
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PSD, pleckstrin and Sec7 domain containing
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EFA6, EFA6A, PSD1, TYL
  • Links
    NCBI Gene ID: 5662
    neXtProt AC: NX_A5PKW4
    UniProt: A5PKW4

  • Chr Location
    10q24.32; chr10:102402617-102420164 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 31115
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: PSD
  • Gene Tree
    Psd
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037126 Ensembl Gene Model | MGI Sequence Detail 15070 C57BL/6J ±  kb
transcript ENSMUST00000096029 Ensembl | MGI Sequence Detail 3903 Not Applicable  
polypeptide ENSMUSP00000093729 Ensembl | MGI Sequence Detail 1025 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    Genomic 12
    cDNA 11
    Primer pair 2
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1195274
References
more
  • Summaries
    All 39
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:44719 Perletti L, et al., Identification of a novel gene, PSD, adjacent to NFKB2/lyt-10, which contains Sec7 and pleckstrin-homology domains. Genomics. 1997 Dec 1;46(2):251-9
  • Latest
    J:272623 Kinoshita-Kawada M, et al., A crucial role for Arf6 in the response of commissural axons to Slit. Development. 2019 Feb 4;146(3)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory