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Smc4
Gene Detail
 Symbol
Name
ID
Smc4
structural maintenance of chromosomes 4
MGI:1917349
Synonyms 2500002A22Rik, Smc4l1
Feature Type protein coding gene
Genetic Map
Chromosome 3
32.14 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:69004738-69034623 bp, + strand
From VEGA annotation of GRCm38

  29886 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4015  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: SMC
Gene Tree: Smc4

Human
homologs
Human Homolog SMC4, structural maintenance of chromosomes 4
NCBI Gene ID 10051
neXtProt AC  NX_Q9NTJ3
Human Synonyms  CAPC, CAP-C, hCAP-C, SMC-4, SMC4L1
Human Chr (Location)  3q26.1; chr3:160399304-160434967 (+)  GRCh38
Alleles
and
phenotypes
All alleles(27) : Gene trapped(25) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cell cycle, cell division, ...
Component chromosome, condensin complex, ...
Function ATP binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (249)    Tissues (113)    Images (37)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 249
cDNA source data(305)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(305) cDNA(305)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000024475 (Evidence)
Ensembl Gene ModelENSMUSG00000034349 (Evidence)
Entrez Gene70099 (Evidence)
UniGene206841
DFCITC1572038, TC1615577
DoTSDT.494422, DT.94405898, DT.94405900
NIA Mouse Gene IndexU003319
PDB3L51
Consensus CDS ProjectCCDS17401.1
International Mouse Knockout Project StatusSmc4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024475 VEGA Gene Model | MGI Sequence Detail 29886 C57BL/6J ±  kb
transcript OTTMUST00000060029 VEGA | MGI Sequence Detail 4316 Not Applicable 
polypeptide OTTMUSP00000029262 VEGA | MGI Sequence Detail 1286 Not Applicable 

For the selected sequences
All sequences(78) RefSeq(13) UniProt(7)
Polymorphisms SNPs within 2kb(152 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR003395 RecF/RecN/SMC
InterPro IPR010935 SMCs flexible hinge
InterPro IPR024704 Structural maintenance of chromosomes protein
Protein Ontology PR:000015273 structural maintenance of chromosomes protein 4
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:195518 Pan X, et al., YY1 controls Igkappa repertoire and B-cell development, and localizes with condensin on the Igkappa locus. EMBO J. 2013 Apr 17;32(8):1168-82
All references(40)
Other
accession IDs
MGI:2140067

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory