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Mospd3 Gene Detail
Summary
  • Symbol
    Mospd3
  • Name
    motile sperm domain containing 3
  • Synonyms
    1190005J19Rik, 5133401H10Rik, Gtig2, R124
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916179
    NCBI Gene: 68929
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:137596645-137601058 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 76.59 cM, cytoband Telomere
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916179
protein coding gene Chr5:137596645-137601084 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030233
protein coding gene Chr5:142369834-142374267 (-)
A/J MGP_AJ_G0030201
protein coding gene Chr5:136160004-136165149 (-)
AKR/J MGP_AKRJ_G0030134
protein coding gene Chr5:140591125-140595432 (-)
BALB/cJ MGP_BALBcJ_G0030211
protein coding gene Chr5:137529996-137534200 (-)
C3H/HeJ MGP_C3HHeJ_G0029927
protein coding gene Chr5:141239455-141243732 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030663
protein coding gene Chr5:147625420-147630930 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027881
protein coding gene Chr5:130405030-130408873 (-)
CAST/EiJ MGP_CASTEiJ_G0029337
protein coding gene Chr5:140642934-140646842 (-)
CBA/J MGP_CBAJ_G0029897
protein coding gene Chr5:153503115-153510116 (-)
DBA/2J MGP_DBA2J_G0030048
protein coding gene Chr5:136062389-136066424 (-)
FVB/NJ MGP_FVBNJ_G0030003
protein coding gene Chr5:135270786-135275155 (-)
LP/J MGP_LPJ_G0030137
protein coding gene Chr5:142841892-142847161 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030035
protein coding gene Chr5:156321629-156326897 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030704
protein coding gene Chr5:140436376-140441502 (-)
PWK/PhJ MGP_PWKPhJ_G0029050
protein coding gene Chr5:135152840-135157493 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028886
protein coding gene Chr5:137999248-138003242 (-)
WSB/EiJ MGP_WSBEiJ_G0029410
protein coding gene Chr5:141170525-141174695 (-)



Homology
more
  • Human Ortholog
    MOSPD3, motile sperm domain containing 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    MOSPD3, motile sperm domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDS3, NET30
  • Links
    NCBI Gene ID: 64598
    neXtProt AC: NX_O75425
    UniProt: O75425

  • Chr Location
    7q22.1; chr7:100612102-100615380 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice on some backgrounds display partial neonatal lethality with a thin right ventricular wall and dilated right ventricle. On other backgrounds no cardiac defects are detected.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037221 Ensembl Gene Model | MGI Sequence Detail 4414 C57BL/6J ±  kb
transcript ENSMUST00000111007 Ensembl | MGI Sequence Detail 1318 Not Applicable  
polypeptide ENSMUSP00000106636 Ensembl | MGI Sequence Detail 235 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 39
    Genomic 1
    cDNA 38

    Microarray probesets 3
Other
Accession IDs
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MGI:1274791, MGI:1925344
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:31729 Forrester LM, et al., An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1677-82
  • Latest
    J:176132 O'Leary J, et al., Global analysis of gene expression in the developing brain of gtf2ird1 knockout mice. PLoS One. 2011;6(8):e23868

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory