About   Help   FAQ
Cilp2 Gene Detail
Summary
  • Symbol
    Cilp2
  • Name
    cartilage intermediate layer protein 2
  • Synonyms
    1110031K21Rik, CLIP-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915959
    NCBI Gene: 68709
Location & Maps
more
  • Sequence Map
    Chr8:69880369-69887687 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7319 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 34.01 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CILP2, cartilage intermediate layer protein 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CILP2, cartilage intermediate layer protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLIP-2
  • Links
    NCBI Gene ID: 148113
    neXtProt AC: NX_Q8IUL8

  • Chr Location
    19p13.11; chr19:19538265-19546659 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 17713
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: CILP2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Cilp2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Other Mouse Links
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033966 VEGA Gene Model | MGI Sequence Detail 7319 C57BL/6J ±  kb
transcript OTTMUST00000085702 VEGA | MGI Sequence Detail 4314 Not Applicable  
polypeptide OTTMUSP00000046327 VEGA | MGI Sequence Detail 1162 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    82 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142398
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:177564 Bernardo BC, et al., Cartilage Intermediate Layer Protein 2 (CILP-2) Is Expressed in Articular and Meniscal Cartilage and Down-regulated in Experimental Osteoarthritis. J Biol Chem. 2011 Oct 28;286(43):37758-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory