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Cilp2 Gene Detail
Summary
  • Symbol
    Cilp2
  • Name
    cartilage intermediate layer protein 2
  • Synonyms
    1110031K21Rik, CLIP-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915959
    NCBI Gene: 68709
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:69880366-69887392 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 34.01 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    77 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915959
protein coding gene Chr8:69880366-69887687 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033680
protein coding gene Chr8:70109511-70116826 (-)
A/J MGP_AJ_G0033663
protein coding gene Chr8:67261478-67268796 (-)
AKR/J MGP_AKRJ_G0033588
protein coding gene Chr8:69168130-69175448 (-)
BALB/cJ MGP_BALBcJ_G0033659
protein coding gene Chr8:67487753-67495070 (-)
C3H/HeJ MGP_C3HHeJ_G0033369
protein coding gene Chr8:69829419-69836736 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034176
protein coding gene Chr8:72777397-72784739 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031120
protein coding gene Chr8:62085361-62092632 (-)
CAST/EiJ MGP_CASTEiJ_G0032694
protein coding gene Chr8:69289410-69296778 (-)
CBA/J MGP_CBAJ_G0033347
protein coding gene Chr8:75415417-75422734 (-)
DBA/2J MGP_DBA2J_G0033501
protein coding gene Chr8:66987518-66995261 (-)
FVB/NJ MGP_FVBNJ_G0033442
protein coding gene Chr8:66083526-66091364 (-)
LP/J MGP_LPJ_G0033588
protein coding gene Chr8:70159818-70167135 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033486
protein coding gene Chr8:78072631-78079949 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034194
protein coding gene Chr8:69350110-69357427 (-)
PWK/PhJ MGP_PWKPhJ_G0032402
protein coding gene Chr8:66272320-66279834 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032238
protein coding gene Chr8:68326322-68333688 (-)
WSB/EiJ MGP_WSBEiJ_G0032809
protein coding gene Chr8:69719066-69726383 (-)



Homology
more
  • Human Ortholog
    CILP2, cartilage intermediate layer protein 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CILP2, cartilage intermediate layer protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLIP-2
  • Links
    NCBI Gene ID: 148113
    neXtProt AC: NX_Q8IUL8
    UniProt: Q8IUL8

  • Chr Location
    19p13.11; chr19:19538265-19546659 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 17713
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CILP2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68709 NCBI Gene Model | MGI Sequence Detail 7027 C57BL/6J ±  kb
transcript NM_026818 RefSeq | MGI Sequence Detail 4022 Not Specified  
polypeptide D3Z7H8 UniProt | EBI | MGI Sequence Detail 1162 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142398
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:177564 Bernardo BC, et al., Cartilage Intermediate Layer Protein 2 (CILP-2) Is Expressed in Articular and Meniscal Cartilage and Down-regulated in Experimental Osteoarthritis. J Biol Chem. 2011 Oct 28;286(43):37758-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory