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Eqtn Gene Detail
Summary
  • Symbol
    Eqtn
  • Name
    equatorin, sperm acrosome associated
  • Synonyms
    1700028B15Rik, 4930579C15Rik, Afaf, equatorin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915003
    NCBI Gene: 67753
  • Gene Overview
    MyGene.info: EQTN
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:94907267-94928843 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 43.34 cM, cytoband C5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    261 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915003
protein coding gene Chr4:94875698-94929952 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028454
protein coding gene Chr4:94956330-94972528 (-)
A/J MGP_AJ_G0028417
protein coding gene Chr4:91632303-91647217 (-)
AKR/J MGP_AKRJ_G0028364
protein coding gene Chr4:93826345-93841972 (-)
BALB/cJ MGP_BALBcJ_G0028435
protein coding gene Chr4:91876875-91891397 (-)
C3H/HeJ MGP_C3HHeJ_G0028148
protein coding gene Chr4:94646028-94660731 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028874
protein coding gene Chr4:98605709-98626766 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026168
protein coding gene Chr4:87140579-87154354 (-)
CAST/EiJ MGP_CASTEiJ_G0027588
protein coding gene Chr4:92507504-92523508 (-)
CBA/J MGP_CBAJ_G0028117
protein coding gene Chr4:101599126-101617835 (-)
DBA/2J MGP_DBA2J_G0028267
protein coding gene Chr4:91420328-91439940 (-)
FVB/NJ MGP_FVBNJ_G0028234
protein coding gene Chr4:90287224-90308974 (-)
LP/J MGP_LPJ_G0028367
protein coding gene Chr4:95275281-95290837 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028262
protein coding gene Chr4:107367069-107389104 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028912
protein coding gene Chr4:94107144-94127210 (-)
PWK/PhJ MGP_PWKPhJ_G0027313
protein coding gene Chr4:89570426-89585337 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027134
protein coding gene Chr4:91522934-91537839 (-)
WSB/EiJ MGP_WSBEiJ_G0027666
protein coding gene Chr4:94257548-94272570 (-)



Homology
more
  • Human Ortholog
    EQTN, equatorin
  • Vertebrate Orthologs
    7
  • Human Ortholog
    EQTN, equatorin
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AFAF, C9orf11, SPACA8
  • Links
    NCBI Gene ID: 54586
    neXtProt AC: NX_Q9NQ60
    UniProt: Q9NQ60

  • Chr Location
    9p21.2; chr9:27284654-27297139 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    3 involving Eqtn
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028575 Ensembl Gene Model | MGI Sequence Detail 21577 C57BL/6J ±  kb
transcript ENSMUST00000030309 Ensembl | MGI Sequence Detail 1074 Not Applicable  
polypeptide ENSMUSP00000030309 Ensembl | MGI Sequence Detail 337 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 1
    cDNA 7

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916718, MGI:2140689
References
more
  • Summaries
    All 33
    Gene Ontology 9
    Phenotypes 5
  • Earliest
    J:177032 Toshimori K, et al., An MN9 antigenic molecule, equatorin, is required for successful sperm-oocyte fusion in mice. Biol Reprod. 1998 Jul;59(1):22-9
  • Latest
    J:219150 Hao J, et al., Equatorin is not essential for acrosome biogenesis but is required for the acrosome reaction. Biochem Biophys Res Commun. 2014 Feb 21;444(4):537-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory