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Borcs7 Gene Detail
Summary
  • Symbol
    Borcs7
  • Name
    BLOC-1 related complex subunit 7
  • Synonyms
    2010012O05Rik, 4930569L17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913689
    NCBI Gene: 66439
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:46689906-46703382 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 38.97 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    59 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913689
protein coding gene Chr19:46689906-46703382 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025215
protein coding gene Chr19:46442160-46458846 (+)
A/J MGP_AJ_G0025191
protein coding gene Chr19:44115816-44129056 (+)
AKR/J MGP_AKRJ_G0025160
protein coding gene Chr19:45548612-45565936 (+)
BALB/cJ MGP_BALBcJ_G0025186
protein coding gene Chr19:44169018-44182845 (+)
C3H/HeJ MGP_C3HHeJ_G0024946
protein coding gene Chr19:45730289-45745755 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025629
protein coding gene Chr19:47554792-47569552 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023043
protein coding gene Chr19:43358104-43369825 (+)
CAST/EiJ MGP_CASTEiJ_G0024411
protein coding gene Chr19:45545645-45561898 (+)
CBA/J MGP_CBAJ_G0024926
protein coding gene Chr19:49947747-49965094 (+)
DBA/2J MGP_DBA2J_G0025058
protein coding gene Chr19:43935311-43949184 (+)
FVB/NJ MGP_FVBNJ_G0025019
protein coding gene Chr19:43719353-43734625 (+)
LP/J MGP_LPJ_G0025144
protein coding gene Chr19:46324229-46340449 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025050
protein coding gene Chr19:49284364-49298334 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025687
protein coding gene Chr19:45670386-45684795 (+)
PWK/PhJ MGP_PWKPhJ_G0024160
protein coding gene Chr19:43890058-43905478 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023964
protein coding gene Chr19:44316694-44330646 (+)
WSB/EiJ MGP_WSBEiJ_G0024481
protein coding gene Chr19:45815439-45831799 (+)



Homology
more
  • Human Ortholog
    BORCS7, BLOC-1 related complex subunit 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BORCS7, BLOC-1 related complex subunit 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C10orf32
  • Links
    NCBI Gene ID: 119032
    neXtProt AC: NX_Q96B45
    UniProt: Q96B45

  • Chr Location
    10q24.32; chr10:102854210-102864961 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 16941
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BORCS7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66439 NCBI Gene Model | MGI Sequence Detail 13477 C57BL/6J ±  kb
transcript NM_025563 RefSeq | MGI Sequence Detail 2176 C57BL/6  
polypeptide Q9CRC6 UniProt | EBI | MGI Sequence Detail 105 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR032143 BLOC-1-related complex subunit 7
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 6
Other
Accession IDs
less
MGI:1923149, MGI:2147518, MGI:2147564
References
more
  • Summaries
    All 27
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:271219 Snouwaert JN, et al., A Mutation in the Borcs7 Subunit of the Lysosome Regulatory BORC Complex Results in Motor Deficits and Dystrophic Axonopathy in Mice. Cell Rep. 2018 Jul 31;24(5):1254-1265

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory