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Bcl2l10 Gene Detail
Summary
  • Symbol
    Bcl2l10
  • Name
    Bcl2-like 10
  • Synonyms
    Boo, Diva
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330841
    NCBI Gene: 12049
  • Gene Overview
    MyGene.info: BCL2L10
Location & Maps
more
  • Sequence Map
    Chr9:75347758-75351632 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3875 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 42.30 cM, cytoband D
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    BCL2L10, BCL2 like 10
  • Vertebrate Orthologs
    6
  • Human Ortholog
    BCL2L10, BCL2 like 10
    Orthology source: HomoloGene
  • Synonyms
    bcl2-L-10, BCL-B, Boo, Diva
  • Links
    NCBI Gene ID: 10017
    neXtProt AC: NX_Q9HD36

  • Chr Location
    15q21; chr15:52109269-52113042 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Bcl2l10
Mice homozygous for a targeted mutation exhibit no obvious abnormalities. They are viable and fertile with normal reproductive capacity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032191 Ensembl Gene Model | MGI Sequence Detail 3875 C57BL/6J ±  kb
transcript ENSMUST00000034709 Ensembl | MGI Sequence Detail 1220 Not Applicable  
polypeptide ENSMUSP00000034709 Ensembl | MGI Sequence Detail 191 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    28 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    Genomic 1
    cDNA 66

    Microarray probesets 3
Other
Accession IDs
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MGI:2142940, MGI:2143221, MGI:2143426
References
more
  • Summaries
    All 29
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:51315 Inohara N, et al., Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death. J Biol Chem. 1998 Dec 4;273(49):32479-86
  • Latest
    J:185833 Fernandes R, et al., NLRP5 mediates mitochondrial function in mouse oocytes and embryos. Biol Reprod. 2012;86(5):138, 1-10

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory