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Chchd2 Gene Detail
Summary
  • Symbol
    Chchd2
  • Name
    coiled-coil-helix-coiled-coil-helix domain containing 2
  • Synonyms
    Etohi6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261428
    NCBI Gene: 14004
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:129881161-129887470 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 68.26 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    113 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1261428
protein coding gene Chr5:129881156-129887470 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0030102
protein coding gene Chr5:128325854-128333411 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0030111
protein coding gene Chr5:129676859-129683060 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0030564
protein coding gene Chr5:139098737-139108835 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027789
protein coding gene Chr5:122712864-122719994 (-)
CAST/EiJ MGP_CASTEiJ_G0029237
protein coding gene Chr5:132361043-132370405 (-)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0029948
protein coding gene Chr5:128288894-128297249 (-)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0029935
protein coding gene Chr5:147862024-147878390 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0028951
protein coding gene Chr5:127223076-127227855 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CHCHD2, coiled-coil-helix-coiled-coil-helix domain containing 2
  • Vertebrate Orthologs
    13
  • Human Ortholog
    CHCHD2, coiled-coil-helix-coiled-coil-helix domain containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C7orf17, MIX17B, MNRR1, NS2TP, PARK22
  • Links
    NCBI Gene ID: 51142
    neXtProt AC: NX_Q9Y6H1
    UniProt: Q9Y6H1

  • Chr Location
    7p11.2; chr7:56101562-56106630 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 49449
    1 human;2 mouse;2 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;2 macaque, rhesus
  • HCOP
    human homology predictions: CHCHD2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Chchd2
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14004 NCBI Gene Model | MGI Sequence Detail 6310 C57BL/6J ±  kb
transcript NM_024166 RefSeq | MGI Sequence Detail 910 C57BL/6  
polypeptide Q9D1L0 UniProt | EBI | MGI Sequence Detail 153 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031808 coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140417
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory