Chchd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chchd2
coiled-coil-helix-coiled-coil-helix domain containing 2
MGI:1261428

21 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chchd2^em1(IMPC)Mbp/Chchd2^em1(IMPC)Mbp C57BL/6NCrl-Chchd2^em1(IMPC)Mbp/MbpMmucd	abnormal coat/ hair morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged testis	J:211773
	small liver	J:211773
Chchd2^tm1Noha/Chchd2^tm1Noha C57BL/6-Chchd2^tm1Noha	abnormal mitochondrial matrix morphology	J:307383
	abnormal mitochondrial shape	J:307383
	abnormal motor coordination/balance	J:307383
	decreased dopaminergic neuron number	J:307383
	decreased mitochondrial size	J:307383
	disorganized mitochondrial cristae	J:307383
	normal growth/size/body region phenotype	J:307383
	impaired autophagy	J:307383
	impaired coordination	J:307383
	Lewy bodies	J:307383
	normal mortality/aging	J:307383
	normal nervous system phenotype	J:307383
Chchd2^tm1Noha/Chchd2^tm1Noha involves: C57BL/6	no abnormal phenotype detected	J:251684

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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