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Barx2
Gene Detail
 Symbol
Name
ID
Barx2
BarH-like homeobox 2
MGI:109617
Synonyms 2310006E12Rik, Barx2b
Feature Type protein coding gene
Genetic Map
Chromosome 9
17.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:31846097-31913462 bp, - strand
From VEGA annotation of GRCm38

  67366 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2715  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Barx2

Human
homologs
Human Homolog BARX2, BARX homeobox 2
NCBI Gene ID 8538
neXtProt AC  NX_Q9UMQ3
Human Chr (Location)  11q25; chr11:129375986-129452279 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from APF )
 
Mice homozygous for a targeted gene deletion exhibit short whiskers at birth, defective juvenile hair follicle remodeling, and short adult hair. Fifty percent of homozygotes are born with open eyelids.
 
Alleles Annotated to Human Diseases(1)    Phenotype Images(1)
Interactions
Barx2 interacts with 73 markers (Mir30c-1, Mir30c-2, Mir124a-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process cartilage condensation, catagen, ...
Component mitochondrion, nucleus, ...
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (312)    Tissues (131)    Images (57)
Theiler Stages: 15, 16, 17, 18, 19, 20, 21, 22, 23, 28
Assay TypeResults
Immunohistochemistry 5
RNA in situ 252
In situ reporter (knock in) 12
Northern blot 9
Western blot 3
RT-PCR 11
RNase protection 20
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(20) cDNA(17) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037222 (Evidence)
Ensembl Gene ModelENSMUSG00000032033 (Evidence)
Entrez Gene12023 (Evidence)
UniGene261044
DFCITC1590628, TC1698392, TC1712767
DoTSDT.91321077, DT.91327424, DT.91342096
NIA Mouse Gene IndexU030650
Consensus CDS ProjectCCDS52750.1
International Mouse Knockout Project StatusBarx2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037222 VEGA Gene Model | MGI Sequence Detail 67366 C57BL/6J ±  kb
transcript OTTMUST00000095990 VEGA | MGI Sequence Detail 1915 Not Applicable 
polypeptide OTTMUSP00000053585 VEGA | MGI Sequence Detail 283 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(233 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000047 Helix-turn-helix motif
InterPro IPR017970 Homeobox, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000004646 homeobox protein BarH-like 2
References (Earliest) J:39325 Jones FS, et al., Barx2, a new homeobox gene of the Bar class, is expressed in neural and craniofacial structures during development. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2632-7
(Latest) J:199186 Juuri E, et al., Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64
All references(49)
Other
accession IDs
MGD-MRK-39616, MGI:1916722

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory