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Meis2 Gene Detail
Summary
  • Symbol
    Meis2
  • Name
    Meis homeobox 2
  • Synonyms
    A430109D20Rik, Meis2, Mrg1, Stra10
  • Feature Type
    protein coding gene
  • IDs
    MGI:108564
    NCBI Gene: 17536
  • Gene Overview
    MyGene.info: MEIS2
Location & Maps
more
  • Sequence Map
    Chr2:115863064-116065839 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      202776 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 58.28 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    MEIS2, Meis homeobox 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MEIS2, Meis homeobox 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HsT18361, MRG1
  • Links
    NCBI Gene ID: 4212
    neXtProt AC: NX_O14770

  • Chr Location
    15q14; chr15:36891021-37101334 (-)  GRCh38.p2
  • HomoloGene
    Vertebrate Homology Class 7846
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: MEIS2
  • Gene Tree
    Meis2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    16
  • Chemically induced (other)
    1
  • Gene trapped
    13
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Meis2
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    247
  • Tissues
    227
  • cDNA Data
    34
  • Literature Summary
    94
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015219 VEGA Gene Model | MGI Sequence Detail 202776 C57BL/6J ±  kb
transcript OTTMUST00000036124 VEGA | MGI Sequence Detail 2831 Not Applicable  
polypeptide OTTMUSP00000016227 VEGA | MGI Sequence Detail 477 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1258 from dbSNP Build 142
  • RFLP
    2
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 43
    Genomic 1
    cDNA 34
    Primer pair 3
    Other 5

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-36505, MGD-MRK-37608, MGI:107925, MGI:2442113
References
more
  • Summaries
    All 128
    Developmental Gene Expression 94
    Gene Ontology 15
    Phenotypes 7
  • Earliest
    J:28316 Bouillet P, et al., Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2). Dev Biol. 1995 Aug;170(2):420-33
  • Latest
    J:234018 Singh S, et al., Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition. Elife. 2016;5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory