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Symbol Name ID |
Meis2
Meis homeobox 2 MGI:108564 |
| Darker colors indicate more annotations |
| Human Phenotypes | High anterior hairline |
Microcephaly |
Large forehead |
Narrow forehead |
Tented upper lip vermilion |
Thin upper lip vermilion |
Cleft upper lip |
Cleft palate |
Sparse eyebrow |
Highly arched eyebrow |
Laterally extended eyebrow |
Upslanted palpebral fissure |
| Disease(s) Associated with MEIS2 | ||||||||||||
| cleft palate, cardiac defects, and intellectual disabillity |
| Mouse Phenotypes | absent maxillary shelf |
absent palatine bone horizontal plate |
absent palate bones |
abnormal palatal mesenchymal cell proliferation |
abnormal palatal shelf elevation |
abnormal palate morphology |
abnormal palatal rugae morphology |
cleft soft palate |
cleft secondary palate |
submucous cleft palate |
abnormal tongue muscle morphology |
decreased tongue size |
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| Availability | Mouse Genotype | ||||||||||||
| H2az2Tg(Wnt1-cre)11Rth/H2az2+ Meis2tm1.1Zkoz/Meis2tm1.1Zkoz (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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