Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of myeloid cell differentiation. Acts upstream of or within eye development and visual learning. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb bud; and sensory organ. Human ortholog(s) of this gene implicated in cleft palate; cleft palate, cardiac defects, and intellectual disabillity; learning disability; open-angle glaucoma; and orofacial cleft. Orthologous to human MEIS2 (Meis homeobox 2).