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Pip5k1b
Gene Detail
Symbol

Name
ID
Pip5k1b
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
MGI:107930
Synonyms
Pipk5b
Feature Type
protein coding gene
Genetic Map
Chromosome 19
19.44 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:24294794-24555872 bp, - strand
From VEGA annotation of GRCm38

  261079 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:100644  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phosphatidylinositol-4-phosphate 5-kinase type II alpha
Gene Tree: Pip5k1b

Human
homologs
Human Homolog PIP5K1B, phosphatidylinositol-4-phosphate 5-kinase, type I, beta
NCBI Gene ID 8395
neXtProt AC  NX_O14986
Human Synonyms  MSS4, STM7
Human Chr (Location)  9q13; chr9:68705332-69009176 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(12) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit enhanced passive cutaneous and systemic anaphylaxis.
 
Interactions
Pip5k1b interacts with 208 markers (Mir10b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (186)    Tissues (134)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 181
Northern blot 1
RT-PCR 4
cDNA source data(24)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) cDNA(25) Primer pair(1) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000031802 (Evidence)
Ensembl Gene ModelENSMUSG00000024867 (Evidence)
Entrez Gene18719 (Evidence)
UniGene217214
DFCITC1590827, TC1580526
DoTSDT.94140730, DT.530826, DT.101341641
NIA Mouse Gene IndexU038927
EC2.7.1.68
Consensus CDS ProjectCCDS37940.1
International Mouse Knockout Project StatusPip5k1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031802 VEGA Gene Model | MGI Sequence Detail 261079 C57BL/6J ±  kb
transcript OTTMUST00000078826 VEGA | MGI Sequence Detail 2573 Not Applicable 
polypeptide OTTMUSP00000041954 VEGA | MGI Sequence Detail 539 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(3777 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023610 Phosphatidylinositol-4-phosphate 5-kinase
InterPro IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
InterPro IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
InterPro IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
InterPro IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain
Protein Ontology PR:000012745 phosphatidylinositol 4-phosphate 5-kinase type-1 beta
References
(Earliest) J:35632 Ishihara H, et al., Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol-4-phosphate 5-kinase. J Biol Chem. 1996 Sep 27;271(39):23611-4
(Latest) J:214303 Wright BD, et al., The lipid kinase PIP5K1C regulates pain signaling and sensitization. Neuron. 2014 May 21;82(4):836-47
All references(62)
Other
accession IDs
MGD-MRK-36510, MGI:2147609

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory