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Pip5k1b
Gene Detail
Symbol

Name
ID
Pip5k1b
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
MGI:107930
Synonyms
Pipk5b
Feature Type
protein coding gene
Genetic Map
Chromosome 19
19.44 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:24294794-24555872 bp, - strand
From VEGA annotation of GRCm38

  261079 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:100644  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PIP5K1B
Protein SuperFamily: phosphatidylinositol-4-phosphate 5-kinase type II alpha
Gene Tree: Pip5k1b

Human
homologs
PIP5K1B, phosphatidylinositol-4-phosphate 5-kinase, type I, beta
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8395
neXtProt AC: NX_O14986

Human Synonyms: MSS4, STM7

Human Chr (Location): 9q13; chr9:68705217-69009176 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(18) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit enhanced passive cutaneous and systemic anaphylaxis.
 
Interactions
Pip5k1b interacts with 208 markers (Mir10b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (186)    Tissues (134)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 181
Northern blot 1
RT-PCR 4
cDNA source data(24)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase pip5k1b    NEW 
Molecular
reagents
All nucleic(27) cDNA(25) Primer pair(1) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000031802 (Evidence)
Ensembl Gene Model ENSMUSG00000024867 (Evidence)
Entrez Gene 18719 (Evidence)
UniGene 217214
DFCI TC1580526, TC1590827
DoTS DT.101341641, DT.530826, DT.94140730
NIA Mouse Gene Index U038927
EC 2.7.1.68
Consensus CDS Project CCDS37940.1
International Mouse Phenotyping Consortium Status Pip5k1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031802 VEGA Gene Model | MGI Sequence Detail 261079 C57BL/6J ±  kb
transcript OTTMUST00000078826 VEGA | MGI Sequence Detail 2573 Not Applicable 
polypeptide OTTMUSP00000041954 VEGA | MGI Sequence Detail 539 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(3777 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023610 Phosphatidylinositol-4-phosphate 5-kinase
InterPro IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
InterPro IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
InterPro IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
InterPro IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain
Protein Ontology PR:000012745 phosphatidylinositol 4-phosphate 5-kinase type-1 beta
References
(Earliest) J:35632 Ishihara H, et al., Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol-4-phosphate 5-kinase. J Biol Chem. 1996 Sep 27;271(39):23611-4
(Latest) J:220524 Pehrson JG, et al., Mice without MacroH2A Histone Variants. Mol Cell Biol. 2014;34(24):4523-33
All references(62)
Other
accession IDs
MGD-MRK-36510, MGI:2147609

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory