About   Help   FAQ
Adipoq
Gene Detail
 Symbol
Name
ID
Adipoq
adiponectin, C1Q and collagen domain containing
MGI:106675
Synonyms Acdc, Acrp30, adipo, adiponectin, apM1, APN, GBP28
Feature Type protein coding gene
Genetic Map
Chromosome 16
13.96 cM, cytoband B3-B4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:23146536-23158028 bp, + strand
From VEGA annotation of GRCm38

  11493 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3525  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: complement subcomponent C1q chain A
Gene Tree: Adipoq

Human
homologs
Human Homolog ADIPOQ, adiponectin, C1Q and collagen domain containing
NCBI Gene ID 9370
neXtProt AC  NX_Q15848
Human Synonyms  ACDC, ACRP30, ADIPQTL1, ADPN, APM1, APM-1, GBP28
Human Chr (Location)  3q27; chr3:186842674-186858463 (+)  GRCh38
Alleles
and
phenotypes
All alleles(8) : Targeted(8)
 
Homozygotes for targeted null mutations exhibit increased beta-oxidation in muscle and liver, impaired free fatty acid clearance, and moderate insulin resistance. Heterozygotes show mild insulin resistance.
 
Phenotype Images(2)
Gene Ontology
(GO)
classifications
All GO classifications: (95 annotations)
Process adiponectin-activated signaling pathway, brown fat cell differentiation, ...
Component cell surface, collagen, ...
Function hormone activity, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (41)    Tissues (26)    Images (6)
Theiler Stages: 10, 18, 21, 23, 25, 28
Assay TypeResults
RNA in situ 3
Northern blot 9
Western blot 2
RT-PCR 27
cDNA source data(71)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(76) Genomic(1) cDNA(73) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000035780 (Evidence)
Ensembl Gene ModelENSMUSG00000022878 (Evidence)
Entrez Gene11450 (Evidence)
UniGene3969
DFCITC1578928
DoTSDT.536006
NIA Mouse Gene IndexU016957
PDB1C3H, 1C28
Consensus CDS ProjectCCDS28075.1
International Mouse Knockout Project StatusAdipoq
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035780 VEGA Gene Model | MGI Sequence Detail 11493 C57BL/6J ±  kb
transcript OTTMUST00000091562 VEGA | MGI Sequence Detail 1292 Not Applicable 
polypeptide OTTMUSP00000050447 VEGA | MGI Sequence Detail 247 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008160 Collagen triple helix repeat
InterPro IPR001073 Complement C1q protein
InterPro IPR008983 Tumour necrosis factor-like domain
Protein Ontology PR:000003777 adiponectin
References (Earliest) J:32963 Scherer PE, et al., A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem. 1995 Nov 10;270(45):26746-9
(Latest) J:204247 Kasahara DI, et al., Role of the adiponectin binding protein, T-cadherin (cdh13), in pulmonary responses to subacute ozone. PLoS One. 2013;8(6):e65829
All references(201)
Other
accession IDs
MGD-MRK-35134

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory