Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Enables several functions, including hormone activity; identical protein binding activity; and protein serine/threonine kinase activator activity. Involved in several processes, including endocrine signaling; negative regulation of cold-induced thermogenesis; and negative regulation of signal transduction. Acts upstream of or within with a positive effect on gene expression. Acts upstream of or within several processes, including brown fat cell differentiation; negative regulation of gluconeogenesis; and positive regulation of D-glucose import across plasma membrane. Located in endoplasmic reticulum and extracellular region. Is expressed in several structures, including adipose tissue; blastocyst-stage conceptus; gut; reproductive system; and serum. Human ortholog(s) of this gene implicated in several diseases, including cardiovascular system disease (multiple); liver disease (multiple); primary open angle glaucoma; prostate adenocarcinoma; and type 2 diabetes mellitus. Orthologous to human ADIPOQ (adiponectin, C1Q and collagen domain containing).

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Gene Ontology Evidence Code Abbreviations:

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