GO Annotations Graph

• Symbol: Adipoq
• Name: adiponectin, C1Q and collagen domain containing
• ID: MGI:106675

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0005179	hormone activity	ISO	J:164563
Molecular Function	GO:0005179	hormone activity	IDA	J:93108
Molecular Function	GO:0005179	hormone activity	TAS	J:70692
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	IPI	J:199207
Molecular Function	GO:0042802	identical protein binding	IPI	J:173174
Molecular Function	GO:0042802	identical protein binding	IPI	J:142231
Molecular Function	GO:0042802	identical protein binding	IPI	J:200414
Molecular Function	GO:0042802	identical protein binding	IPI	J:93110
Molecular Function	GO:0042802	identical protein binding	IPI	J:92987
Molecular Function	GO:0042802	identical protein binding	IPI	J:32963
Molecular Function	GO:0042802	identical protein binding	IPI	J:93109
Molecular Function	GO:0042802	identical protein binding	IPI	J:143939
Molecular Function	GO:0005515	protein binding	IPI	J:199207
Molecular Function	GO:0005515	protein binding	IPI	J:142231
Molecular Function	GO:0005515	protein binding	IPI	J:90488
Molecular Function	GO:0005515	protein binding	IPI	J:143939
Molecular Function	GO:0005515	protein binding	IPI	J:92987
Molecular Function	GO:0005515	protein binding	IPI	J:143939
Molecular Function	GO:0005515	protein binding	IPI	J:90488
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0033691	sialic acid binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IDA	J:93109
Molecular Function	GO:0005102	signaling receptor binding	IDA	J:90488
Molecular Function	GO:0005102	signaling receptor binding	IDA	J:93110
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005581	collagen trimer	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:92989
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IDA	J:32963
Cellular Component	GO:0005615	extracellular space	IDA	J:202772
Cellular Component	GO:0005615	extracellular space	IDA	J:93108
Cellular Component	GO:0005615	extracellular space	IDA	J:126780
Cellular Component	GO:0005615	extracellular space	IDA	J:93110
Cellular Component	GO:0005615	extracellular space	IDA	J:81609
Cellular Component	GO:0005615	extracellular space	IDA	J:92988
Cellular Component	GO:0005615	extracellular space	IDA	J:93109
Cellular Component	GO:0005615	extracellular space	IDA	J:86301
Cellular Component	GO:0005615	extracellular space	IDA	J:92987
Cellular Component	GO:0005615	extracellular space	IDA	J:143939
Cellular Component	GO:0005615	extracellular space	IDA	J:92989
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0050873	brown fat cell differentiation	IDA	J:137608
Biological Process	GO:0071320	cellular response to cAMP	ISO	J:155856
Biological Process	GO:0071872	cellular response to epinephrine stimulus	ISO	J:155856
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:155856
Biological Process	GO:0032869	cellular response to insulin stimulus	IGI	J:126780
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	IDA	J:142895
Biological Process	GO:0070994	detection of oxidative stress	IMP	J:136297
Biological Process	GO:0006635	fatty acid beta-oxidation	IMP	J:79122
Biological Process	GO:0019395	fatty acid oxidation	IDA	J:90488
Biological Process	GO:0010467	gene expression	IDA	J:190951
Biological Process	GO:0042593	glucose homeostasis	IDA	J:77479
Biological Process	GO:0042593	glucose homeostasis	IMP	J:77876
Biological Process	GO:0042593	glucose homeostasis	IDA	J:93108
Biological Process	GO:0042593	glucose homeostasis	IMP	J:77479
Biological Process	GO:0006006	glucose metabolic process	IDA	J:90488
Biological Process	GO:0006006	glucose metabolic process	IDA	J:93108
Biological Process	GO:0006006	glucose metabolic process	IMP	J:77876
Biological Process	GO:0006006	glucose metabolic process	IMP	J:77479
Biological Process	GO:0006006	glucose metabolic process	IDA	J:77479
Biological Process	GO:0034383	low-density lipoprotein particle clearance	ISO	J:164563
Biological Process	GO:0045776	negative regulation of blood pressure	ISO	J:164563
Biological Process	GO:0030336	negative regulation of cell migration	IDA	J:169978
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IMP	J:210480
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IMP	J:249877
Biological Process	GO:2000279	negative regulation of DNA biosynthetic process	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:136297
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0045599	negative regulation of fat cell differentiation	ISO	J:164563
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IDA	J:140382
Biological Process	GO:0045721	negative regulation of gluconeogenesis	IDA	J:93108
Biological Process	GO:0030853	negative regulation of granulocyte differentiation	ISO	J:164563
Biological Process	GO:0034115	negative regulation of heterotypic cell-cell adhesion	ISO	J:164563
Biological Process	GO:0046888	negative regulation of hormone secretion	ISO	J:155856
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	IDA	J:142895
Biological Process	GO:0090317	negative regulation of intracellular protein transport	ISO	J:164563
Biological Process	GO:1905598	negative regulation of low-density lipoprotein receptor activity	ISO	J:164563
Biological Process	GO:0010745	negative regulation of macrophage derived foam cell differentiation	ISO	J:164563
Biological Process	GO:0045650	negative regulation of macrophage differentiation	ISO	J:164563
Biological Process	GO:0043407	negative regulation of MAP kinase activity	IDA	J:169978
Biological Process	GO:2000590	negative regulation of metanephric mesenchymal cell migration	IDA	J:169978
Biological Process	GO:0050765	negative regulation of phagocytosis	ISO	J:164563
Biological Process	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	IDA	J:169978
Biological Process	GO:2000584	negative regulation of platelet-derived growth factor receptor-alpha signaling pathway	IDA	J:169978
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	ISO	J:164563
Biological Process	GO:1900121	negative regulation of receptor binding	ISO	J:164563
Biological Process	GO:0050805	negative regulation of synaptic transmission	ISO	J:164563
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	ISO	J:164563
Biological Process	GO:1904753	negative regulation of vascular associated smooth muscle cell migration	ISO	J:164563
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:2000481	positive regulation of cAMP-dependent protein kinase activity	ISO	J:164563
Biological Process	GO:2000481	positive regulation of cAMP-dependent protein kinase activity	IMP	J:136297
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:249877
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:210480
Biological Process	GO:0045923	positive regulation of fatty acid metabolic process	IMP	J:77479
Biological Process	GO:0046326	positive regulation of glucose import	IDA	J:77479
Biological Process	GO:2000467	positive regulation of glycogen (starch) synthase activity	ISO	J:155856
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IDA	J:93109
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IDA	J:93110
Biological Process	GO:0032757	positive regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0110113	positive regulation of lipid transporter activity	ISO	J:164563
Biological Process	GO:2000478	positive regulation of metanephric podocyte development	IMP	J:136297
Biological Process	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	ISO	J:164563
Biological Process	GO:0033034	positive regulation of myeloid cell apoptotic process	ISO	J:164563
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:155856
Biological Process	GO:0010739	positive regulation of protein kinase A signaling	ISO	J:164563
Biological Process	GO:0045860	positive regulation of protein kinase activity	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:2000534	positive regulation of renal albumin absorption	ISO	J:164563
Biological Process	GO:2000534	positive regulation of renal albumin absorption	IMP	J:136297
Biological Process	GO:0009967	positive regulation of signal transduction	IDA	J:93109
Biological Process	GO:0009967	positive regulation of signal transduction	IDA	J:93110
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0010906	regulation of glucose metabolic process	ISO	J:164563
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0009749	response to glucose	IMP	J:77876
Biological Process	GO:0009749	response to glucose	IMP	J:77479
Biological Process	GO:0009749	response to glucose	IDA	J:77479
Biological Process	GO:0034612	response to tumor necrosis factor	ISO	J:164563